Grantee Research Project Results

Community-Based Participatory Research Project

EPA Grant Number: R831709C003
Subproject: this is subproject number 003 , established and managed by the Center Director under grant R831709
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
Center: Center for Air, Climate, and Energy Solutions
Center Director: Robinson, Allen
Title: Community-Based Participatory Research Project
Investigators: Faustman, Elaine
Institution: University of Washington
EPA Project Officer: Callan, Richard
Project Period: November 1, 2003 through October 31, 2008 (Extended to October 31, 2010)
RFA: Centers for Children's Environmental Health and Disease Prevention Research (2003) RFA Text | Recipients Lists
Research Category: Children's Health , Human Health

Objective:

The objectives of the research project are to: (1) intervene to reduce children’s exposure to pesticides, including the development of a culturally appropriate intervention to break the take-home pathway; and (2) foster partnerships between academic researchers and the community in which information requested by the community and basic research deficiencies/gaps are translated into studies that address the health needs of both.

As a result of receipt of donor funds, we were able to increase the scope of work for this research project to include collection of additional biological specimens that will enhance the project further. The additional tasks include: (1) comparing the levels of organophosphorus pesticide (OP) parent compounds in the blood of adult farmworkers and nonfarmworkers, adjusting for the multiple pathways; (2) compare levels of pesticide residues in saliva to those in urine and blood to determine reliability and validity of data and to assess more accurately the presence of Ops; (3) conduct blood analysis through finger sticks to ascertain cholinesterase levels; and (4) conduct analysis of buccal cell samples in adults and children of farmworkers and nonfarmworkers to gain a better understanding of the mechanisms of toxicity of OPs.

Publications and Presentations:

Publications have been submitted on this subproject: View all 14 publications for this subproject | View all 175 publications for this center

Journal Articles:

Journal Articles have been submitted on this subproject: View all 10 journal articles for this subproject | View all 107 journal articles for this center

Supplemental Keywords:

children’s health, epidemiology, genetics, health risk assessment, risk assessment, assessment of exposure, asthma, children’s environmental health, diesel exhaust, environmental risks, exposure assessment, genetic mechanisms, genetic risk factors, genetic susceptibility, maternal exposure, nutritional risk factors,, RFA, Health, Scientific Discipline, ENVIRONMENTAL MANAGEMENT, Environmental Chemistry, Health Risk Assessment, Biochemistry, Children's Health, Risk Assessment, health effects, pesticide exposure, environmental health, community-based intervention, developmental neurotoxicity, environmental risks, biological response, Human Health Risk Assessment, children's vulnerablity, assessment of exposure

Progress and Final Reports:

Main Center Abstract and Reports:

R831709 Center for Air, Climate, and Energy Solutions

Subprojects under this Center: (EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
R831709C001 Molecular Mechanisms of Pesticide-Induced Developmental Toxicity
R831709C002 Genetic Susceptibility to Pesticides
R831709C003 Community-Based Participatory Research Project
R831709C004 Pesticide Exposure Pathways Research Project

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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.