Grantee Research Project Results
2003 Progress Report: Nanomaterial-Based Microchip Assays For Continuous Environmental Monitoring
EPA Grant Number: R830900Title: Nanomaterial-Based Microchip Assays For Continuous Environmental Monitoring
Investigators: Wang, Joseph
Institution: New Mexico State University - Main Campus
EPA Project Officer: Hahn, Intaek
Project Period: June 1, 2003 through May 31, 2006
Project Period Covered by this Report: June 1, 2003 through May 31, 2004
Project Amount: $341,000
RFA: Environmental Futures Research in Nanoscale Science Engineering and Technology (2002) RFA Text | Recipients Lists
Research Category: Nanotechnology , Human Health , Safer Chemicals
Objective:
The objective of this project is to address the needs for innovative nanotechnological tools for continuous environmental monitoring of priority pollutants. The project aims to create a novel nanomaterial-based submersible microfluidic device for rapidly, continuously, and economically monitoring different classes of priority pollutants. We wish to exploit the unique properties of metal nanoparticles and carbon nanotubes for enhancing the separation and detection processes, respectively, in microchip environmental assays. We also wish to understand the relationship between the physical and chemical properties of these nanomaterials and the observed behavior. The miniaturized "Laboratory-on-a-Cable" will incorporate all the steps of the analytical protocol into the submersible remotely deployed device.
Progress Summary:
During the first year of this project, we introduced new and innovative nanomaterial-based strategies for enhancing the performance of microchip devices for environmental assays. Carbon nanotubes and carbon nanotubes/copper particle composites have been shown to be useful for enhancing the sensitivity and stability of electrical detectors for microchip devices. Dramatically improved monitoring of hydrazine and phenolic pollutants has been demonstrated. Carbon nanotubes also were shown to be extremely useful for improving the amperometric biosensing and microchip detection of organophosphorus pesticides and the electrochemical detection of hydrogen sulfide. We also addressed the important "World-to-Chip" interface issue and developed a continuous sampling capability based on a novel sharp sample-inlet tip. This was demonstrated in connection with the monitoring of nitroaromatic explosives. Such ability to continuously introduce real samples into micrometer channels would make "Lab-on-a-Chip" devices compatible with real-life environmental applications. These developments indicate that nanomaterials and microchip devices hold great promise for field monitoring of priority pollutants.
Future Activities:
We will examine the use of different nanomaterials for enhancing different elements of "Lab-on-a-Chip" devices and will design a submersible microfluidic device for rapidly, continuously, and economically monitoring different classes of priority pollutants.
Journal Articles on this Report : 5 Displayed | Download in RIS Format
| Other project views: | All 19 publications | 13 publications in selected types | All 13 journal articles |
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Chen G, Wang J. Fast and simple sample introduction for capillary electrophoresis microsystems. Analyst 2004;129(6):507-511. |
R830900 (2003) R830900 (2004) |
not available |
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Lawrence NS, Deo RP, Wang J. Electrochemical determination of hydrogen sulfide at carbon nanotube modified electrodes. Analytica Chimica Acta 2004;517(1-2):131-137 |
R830900 (2003) R830900 (2004) |
not available |
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Wang J, Chen G, Chatrathi MP, Musameh M. Capillary electrophoresis microchip with a carbon nanotube-modified electrochemical detector. Analytical Chemistry 2004;76(2):298-302 |
R830900 (2003) R830900 (2004) |
not available |
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Wang J, Chen G, Wang M, Chatrathi MP. Carbon-nanotube/copper composite electrodes for capillary electrophoresis microchip detection of carbohydrates. Analyst 2004;129(6):512-515 |
R830900 (2003) R830900 (2004) |
not available |
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Wang J, Chen G, Muck A, Chatrathi M, Mulchandani A, Chen W. Microchip enzymatic assay of organophosphate nerve agents. Analytica Chimica Acta 2004; 505(1): 183-187. |
R830900 (2003) R830900 (2004) |
not available |
Supplemental Keywords:
nanotechnology, microchip, nanomaterials, environmental monitoring, sensor, carbon nanotubes, continuous monitoring, environmental measurement, microchip assays, nanocontact sensor, nanoengineering, nanosensors., Sustainable Industry/Business, RFA, Ecosystem Protection/Environmental Exposure & Risk, Scientific Discipline, Water, Engineering, Chemistry, & Physics, Monitoring/Modeling, New/Innovative technologies, Environmental Engineering, Environmental Monitoring, carbon nanotubes, environmental measurement, nanoengineering, nanotechnology, nanosensors, analytical chemistry, continous monitoring, continuous monitoring, nanocontact sensorRelevant Websites:
http://www.chemistry.nmsu.edu/~research/sensors/srg/srg.html Exit
Progress and Final Reports:
Original AbstractThe perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.