Grantee Research Project Results
2022 Progress Report: PFAS UNITED: Poly - and Perfluoroalkyl Substances - U.S.National Investigation of Transport & Exposure from Drinking Water and Diet
EPA Grant Number: R839482Title: PFAS UNITED: Poly - and Perfluoroalkyl Substances - U.S.National Investigation of Transport & Exposure from Drinking Water and Diet
Investigators: Higgins, Christopher , Illangasekare, Tissa , Adgate, John L. , Stapleton, Heather , Knappe, Detlef , Hoppin, Jane , Carignan, Courtney
Institution: Colorado School of Mines , Duke University , Michigan State University , University of Colorado at Denver , North Carolina State University
EPA Project Officer: Packard, Benjamin H
Project Period: May 1, 2019 through April 30, 2022 (Extended to March 31, 2024)
Project Period Covered by this Report: May 1, 2022 through April 30,2023
Project Amount: $1,964,375
RFA: National Priorities: Per- and Polyfluoroalkyl Substances (2018) RFA Text | Recipients Lists
Research Category: Ecological Indicators/Assessment/Restoration , Climate Change , Water , Water Quality
Objective:
The goal of this study is to develop a comprehensive set of data related to the fate, transport, and bioaccumulation of poly- and perfluoroalkyl substances (PFASs) and resultant human exposure. This study seeks to fill the data gaps on the fundamental environmental behavior of overlooked PFASs, the uptake into local food sources in impacted communities, and the relevance of that uptake for human exposure to PFASs.
Progress Summary:
As of the four-year mark, we have held one in-person team meeting with all collaborating institutions and four virtual Advisory Board meetings. Thus far in the research we have successfully achieved the following:
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Completed unsaturated vadose zone transport experiments and published results in Environmental Science & Technology.
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Completed Phase 2 and 3 of greenhouse experiments and analysis of Phase 1 and 2 samples and drafted manuscript.
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Completed analysis of market basket samples and began estimating exposure from consumption of local and homegrown foods
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Completed analysis of human biomonitoring samples and published manuscript on source apportionment of serum PFASs in two highly exposed communities in Science of the Total Environment.
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Provided personalized report back of water, serum, soil and food results.
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Ran parallel analysis of UNMIX, PMF and PCLA-MLR to apportion PFAS sources in serum of the new Michigan cohort.
Future Activities:
Complete analysis of Phase 2 and 3 greenhouse experiments to determine crop uptake of PFASs sorbed to soil and publish results.
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Complete correlating the produce data with soil and water data and publish findings of PFAS occurrence in different samples for the North Carolina market basket study.
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Estimate PFAS human exposure through local foods and publish findings of PFAS human exposure assessments for the North Carolina market basket study.
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Complete analysis of TSCF data and PFAS transpiration and translocation experiments and publish results.
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Complete analysis of the passive air and house dust samples collected in Michigan.
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Complete analysis of water contribution and dietary contribution to serum PFAS.
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Complete analysis of the farmer’s market results and publish results.
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Share monthly updates with the community advisory board and meet as needed.
Journal Articles on this Report : 4 Displayed | Download in RIS Format
Other project views: | All 17 publications | 8 publications in selected types | All 8 journal articles |
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Type | Citation | ||
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Herkert NJ, Kassotis CD, Zhang S, Han Y, Pulikkal VF, Sun M, Ferguson PL, Stapleton HM. Characterization of per-and polyfluorinated alkyl substances present in commercial anti-fog products and their in vitro adipogenic activity. Environmental Science & Technology 2022;56(2):1162-73. |
R839482 (2021) R839482 (2022) |
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Stults JF, Choi YJ, Rockwell C, Schaefer CE, Nguyen DD, Knappe DR, Illangasekare TH, Higgins CP. Predicting concentration-and ionic-strength-dependent air–water interfacial partitioning parameters of PFASs using quantitative structure–property relationships (QSPRs). Environmental Science & Technology 2023;57(13):5203-5215. |
R839482 (2022) |
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Carignan CC, Bauer RA, Patterson A, Phomsopha T, Redman E, Stapleton HM, Higgins CP. Self-collection blood test for PFASs:comparing volumetric microsamplers with a traditional serum approach. Environmental Science & Technology 2023; 57(21):7950-7957. |
R839482 (2022) |
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Wallis DJ, Barton KE, Knappe DR, Kotlarz N, McDonough CA, Higgins CP, Hoppin JA, Adgate JL. Source apportionment of serum PFASs in two highly exposed communities. Science of The Total Environment 2023;855:158842. |
R839482 (2022) |
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Supplemental Keywords:
PFAS, drinking water, food, contaminants, exposureRelevant Websites:
Progress and Final Reports:
Original AbstractThe perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.