Grantee Research Project Results
Publications submitted after final report Details for Grant Number R828562
Metabolic Engineering of Solvent Tolerance in Anaerobic Bacteria
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| Reference Type | Reference Title | Journal | Author | Citation | Progress Report Year (Date Added to Report) | Document Sources |
|---|---|---|---|---|---|---|
| Abstract | 247Ex vivo expanded (EYE) peripheral blood progenitor cells (PBPC) demonstrate respiratory burst (RB) and phagocytic capacity: a flow cytometric analysis. | BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION | Tomblyn MR, Guo R, Paniagua M, Eklund EA, Goolsby C, Papoutsakis ET, Miller, WM, Winter JN | Tomblyn MR, Guo R, Paniagua M, Eklund EA, Goolsby C, Papoutsakis ET, Miller WM, Winter JN. 247Ex vivo expanded (EYE) peripheral blood progenitor cells (PBPC) demonstrate respiratory burst (RB) and phagocytic capacity: a flow cytometric analysis. Biology of Blood and Marrow Transplantation 2003;9(2):135. |
R828562 (Final) (04/06/18) |
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| Book Chapter | Gene analysis of clostridia. | None | Tummala SB, Tomas CA, Papoutsakis ET | Tummala SB, Tomas CA, Papoutsakis ET. Gene analysis of clostridia. In: Durre P, ed. Handbook of Clostridia. Boca Raton, FL: CRC Press, 2005, Part I, Chapter 4, pp. 53-70. |
R828562 (Final) (01/10/07) |
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| Journal Article | Modeling pO2 distributions in the bone marrow hematopoietic compartment. I. Krogh's model. | BIOPHYSICAL JOURNAL | Chow DC, Wenning LA, Miller WM, Papoutsakis ET | Chow DC, Wenning LA, Miller WM, Papoutsakis ET. Modeling pO2 distributions in the bone marrow hematopoietic compartment. I. Krogh's model. Biophysical Journal 2001;81(2):675-684. |
R828562 (Final) (04/06/18) |
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| Journal Article | Modeling pO2 distributions in the bone marrow hematopoietic compartment. II. Modified Kroghian models. | BIOPHYSICAL JOURNAL | Chow DC, Wenning LA, Miller WM, Papoutsakis ET | Chow DC, Wenning LA, Miller WM, Papoutsakis ET. Modeling pO2 distributions in the bone marrow hematopoietic compartment. II. Modified Kroghian models.Biophysical Journal 2001;81(2):685-696. |
R828562 (Final) (04/06/18) |
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| Journal Article | Low oxygen tension and autologous plasma enhance T-cell proliferation and CD49d expression density in serum-free media. | CYTOTHERAPY | Haddad H, Papoutsakis ET | Haddad H, Papoutsakis ET. Low oxygen tension and autologous plasma enhance T-cell proliferation and CD49d expression density in serum-free media. Cytotherapy 2001;3(6):435-447. |
R828562 (Final) (04/06/18) |
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| Journal Article | Fermentation characterization and flux analysis of recombinant strains of Clostridium acetobutylicum with an inactivated solR gene. | JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY | Harris LM, Blank L, Desai RP, Welker NE, Papoutsakis ET | Harris LM, Blank L, Desai RP, Welker NE, Papoutsakis ET. Fermentation characterization and flux analysis of recombinant strains of Clostridium acetobutylicum with an inactivated solR gene. Journal of Industrial Microbiology & Biotechnology 2001;27(5):322-328. |
R828562 (Final) (04/06/18) |
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| Journal Article | Northern, morphological, and fermentation analysis of spo0A inactivation and overexpression in Clostridium acetobutylicum<.em> ATCC 824. | JOURNAL OF BACTERIOLOGY | Harris LM, Welker NE, Papoutsakis ET | Harris LM, Welker NE, Papoutsakis ET. Northern, morphological, and fermentation analysis of spo0A inactivation and overexpression in Clostridium acetobutylicum ATCC 824. Journal of Bacteriology 2002;184(13):3586-3597. |
R828562 (Final) (04/06/18) |
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| Journal Article | Differential expression and phosphorylation of distinct STAT3 proteins during granulocytic differentiation. | BLOOD | Hevehan DL, Miller WM, Papoutsakis ET | Hevehan DL, Miller WM, Papoutsakis ET. Differential expression and phosphorylation of distinct STAT3 proteins during granulocytic differentiation. BLood 2002;99(5):1627-1637. |
R828562 (Final) (04/06/18) |
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| Journal Article | Oxygen tension modulates the expression of cytokine receptors, transcription factors, and lineage-specific markers in cultured human megakaryocytes. | EXPERIMENTAL HEMATOLOGY | Mostafa SS, Papoutsakis ET, Miller WM | Mostafa SS, Papoutsakis ET, Miller WM. Oxygen tension modulates the expression of cytokine receptors, transcription factors, and lineage-specific markers in cultured human megakaryocytes. Experimental Hematology 2001;29(7):873-883. |
R828562 (Final) (04/06/18) |
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| Journal Article | DNA Array-Based Transcriptional Analysis of Asporogenous, Nonsolventogenic Clostridium acetobutylicum Strains SKO1 and M5. | JOURNAL OF BACTERIOLOGY | Tomas CA, Alsaker KV, Bonarius HPJ, Hendriksen WT, Yang H, Beamish JA, Paredes CJ, Papoutsakis ET | Tomas CA, Alsaker KV, Bonarius HPJ, Hendriksen WT, Yang H, Beamish JA, Paredes CJ, Papoutsakis ET. DNA array-based transcriptional analysis of asporogenous, nonsolventogenic Clostridium acetobutylicum strains SKO1 and M5. Journal of Bacteriology 2003;185(15):4539-4547. |
R828562 (Final) (04/06/18) |
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| Journal Article | Antisense RNA downregulation of coenzyme A transferase combined with alcohol-aldehyde dehydrogenase overexpression leads to predominantly alcohologenic Clostridium acetobutylicum fermentations. | JOURNAL OF BACTERIOLOGY | Tummala SB, Junne SG, Papoutsakis ET | Tummala SB, Junne SG, Papoutsakis ET. Antisense RNA downregulation of coenzyme A transferase combined with alcohol-aldehyde dehydrogenase overexpression leads to predominantly alcohologenic Clostridium acetobutylicum fermentations. Journal of Bacteriology 2003;185(12):3644-3653. |
R828562 (Final) (04/06/18) |
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| Journal Article | Design of antisense RNA constructs for downregulation of the acetone formation pathway of Clostridium acetobutylicum. | JOURNAL OF BACTERIOLOGY | Tummala SB, Welker NE, Papoutsakis ET | Tummala SB, Welker NE, Papoutsakis ET. Design of antisense RNA constructs for downregulation of the acetone formation pathway of Clostridium acetobutylicum. Journal of Bacteriology 2003;185(6):1923-1934. |
R828562 (Final) (04/06/18) |
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| Journal Article | Higher pH promotes megakaryocytic maturation and apoptosis. | STEM CELLS | Yang H, Miller WM, Papoutsakis ET | Yang H, Miller WM, Papoutsakis ET. Higher pH promotes megakaryocytic maturation and apoptosis. Stem Cells 2002;20(4):320-328. |
R828562 (Final) (04/06/18) |
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| Journal Article | A segmental nearest neighbor normalization and gene identification method gives superior results for DNA-array analysis. | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES | Yang H, Haddad H, Tomas C, Alsaker K, Papoutsakis ET | Yang H, Haddad H, Tomas C, Alsaker K, Papoutsakis ET. A segmental nearest neighbor normalization and gene identification method gives superior results for DNA-array analysis. Proceedings of the National Academy of Sciences 2003;100(3):1122-1127. |
R828562 (Final) (04/06/18) |
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| Patent/Patent Application | Increased cell resistance to toxic organic substances. | None | Papoutsakis ET, Tomas CA, Tesic M, Santiago JY | Papoutsakis ET, Tomas CA, Tesic M, Santiago JY. Increased cell resistance to toxic organic substances. U.S. Patent No. 6,960,465, 2005. |
R828562 (Final) (04/06/18) |
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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.