Grantee Research Project Results
Publications Details for Grant Number R832414C002
Endothelial Cell Responses to PM—In Vitro and In Vivo
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| Reference Type | Citation | Progress Report Year | Document Sources |
|---|---|---|---|
| Journal Article | Aung HH, Lame MW, Gohil K, He G, Denison MS, Rutledge JC, Wilson DW. Comparative gene responses to collected ambient particles in vitro:endothelial responses. Physiological Genomics 2011;43(15):917-929. |
R832414 (Final) R832414C002 (Final) |
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| Journal Article | den Hartigh LJ, Lame MW, Ham W, Kleeman MJ, Tablin F, Wilson DW. Endotoxin and polycyclic aromatic hydrocarbons in ambient fine particulate matter from Fresno, California initiate human monocyte inflammatory responses mediated by reactive oxygen species.Toxicology In Vitro 2010;24(7):1993-2002. |
R832414 (2010) R832414 (Final) R832414C002 (2010) R832414C002 (Final) |
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| Journal Article | Nakayama Wong LS, Lame MW, Jones AD, Wilson DW. Differential cellular responses to protein adducts of naphthoquinone and monocrotaline pyrrole. Chemical Research in Toxicology 2010;23(9):1504-1513. |
R832414 (2010) R832414 (Final) R832414C002 (2010) R832414C002 (Final) |
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| Journal Article | Nakayama Wong LS, Aung HH, Lame MW, Wegesser TC, Wilson DW. Fine particulate matter from urban ambient and wildfire sources from California's San Joaquin Valley initiate differential inflammatory, oxidative stress, and xenobiotic responses in human bronchial epithelial cells. Toxicology In Vitro 2011;25(8):1895-1905. |
R832414 (Final) R832414C002 (Final) |
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| Journal Article | Shen H, Barakat AI, Anastasio C. Generation of hydrogen peroxide from San Joaquin Valley particles in a cell-free solution. Atmospheric Chemistry and Physics 2011;11(2):753-765. |
R832414 (2010) R832414 (Final) R832414C002 (2010) R832414C002 (Final) |
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| Journal Article | Shen H, Anastasio C. Formation of hydroxyl radical from San Joaquin Valley particles extracted in a cell-free surrogate lung fluid. Atmospheric Chemistry and Physics 2011;11(18):9671-9682. |
R832414 (Final) R832414C002 (Final) |
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| Journal Article | Shen H, Anastasio C. A comparison of hydroxyl radical and hydrogen peroxide generation in ambient particle extracts and laboratory metal solutions. Atmospheric Environment 2012;46:665-668. |
R832414 (Final) R832414C002 (Final) |
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| Journal Article | Tablin F, den Hartigh LJ, Aung HH, Lame MW, Kleeman MJ, Ham W, Norris JW, Pombo M, Wilson DW. Seasonal influences on CAPs exposures:differential responses in platelet activation, serum cytokines and xenobiotic gene expression. Inhalation Toxicology 2012;24(8):506-517. |
R832414 (Final) R832414C002 (Final) |
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| Journal Article | Wilson DW, Aung HH, Lame MW, Plummer L, Pinkerton KE, Ham W, Kleeman M, Norris JW, Tablin F. Exposure of mice to concentrated ambient particulate matter results in platelet and systemic cytokine activation. Inhalation Toxicology 2010;22(4):267-276. |
R832414 (2010) R832414 (Final) R832414C002 (Final) R832414C003 (2010) R832414C003 (Final) |
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| Presentation | Aung HH, Lame MW, Gohill K, Rutledge JC, Wilson DW. Particulate matter-induced expression of CYP1A1 gene through the AhR pathway in human aortic endothelial cells. Presented at the American Thoracic Society Annual International Conference, Toronto, Ontario, Canada, May 16-21, 2008. |
R832414 (Final) R832414C002 (2009) R832414C002 (Final) |
not available |
| Presentation | Aung HH, Lame MW, He G, Denison M, Rutledge JC, Wilson DW. Induction of phase I xenobiotic metabolism and pro-inflammatory gene expression in vascular endothelial cell by concentrated ambient particulate matter. Presented at the American Thoracic Society Annual International Conference, New Orleans, LA, May 14-19, 2010. |
R832414 (2010) R832414 (Final) R832414C002 (2010) R832414C002 (Final) |
not available |
| Presentation | Blum A, Lame M, Tablin F, Wilson DW. In vitro effects of particulate matter on human endothelial adhesion molecule expression. Presented at the Merck Meriel Summer Scholars Annual Conference, 2008. |
R832414C002 (2008) R832414C002 (2009) |
not available |
| Presentation | Feliz AM, Lame MW, Kumfer B, Kennedy I, Wilson DW. Interaction of ultra fine particles and transcytosis in human aortic endothelial cells. Presented at the American Thoracic Society Annual International Conference, San Francisco, CA, May 18-23, 2007. |
R832414 (Final) R832414C002 (Final) R832414C004 (2007) |
not available |
| Presentation | Lewis K, Nakayama Wong LS, Lame M, Wilson DW. Endothelial cell responses to environmental particulate matter. Presented at the 2008 Merck-Merial NIH Veterinary Scholars Symposium, East Lansing, MI, July 31-August 3, 2008. |
R832414 (Final) R832414C002 (2008) R832414C002 (2009) R832414C002 (Final) |
not available |
| Presentation | Nakayama Wong LS, Lame MW, Jones AD, Wilson DW. Intracellular oxidation and the translocation of Nrf2 in human pulmonary artery endothelial cells exposed to monocrotaline pyrrole, 1,4-naphthoquinone, and naphthoquinone adducted galectin-1. Presented at the American Thoracic Society International Conference, San Francisco, CA, May 18-23, 2007. |
R832414 (Final) R832414C002 (Final) |
not available |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.