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Grantee Research Project Results

Journal Publications Details for Grant Number R839503

Reducing the reliance on early-life stage testing with relevance to euryhaline fishes: Development and implementation of in-vitro assays predictive of early life stage toxicity and population-level effects in Menidia beryllina

RFA: Advancing Actionable Alternatives to Vertebrate Animal Testing for Chemical Safety Assessment (2018)

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Journal Article (8)
Reference Type Citation Progress Report Year Document Sources
Journal Article Hutton S, Siddiqui S, Pedersen E, Markgraf C, Segarra A, Hladik M, Connon R, Brander S. Multigenerational, Indirect Exposure to Pyrethroids Demonstrates Potential Compensatory Response and Reduced Toxicity at Higher Salinity in Estuarine Fish. ENVIRONMENTAL SCIENCE & TECHNOLOGY 2024;58(5):2224-2235 R839503 (2022)
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Journal Article Mundy PC, Hartz KE, Fulton CA, Lydy MJ, Brander SM, Hung TC, Fangue N, Connon RE. Exposure to permethrin or chlorpyrifos causes differential dose-and time-dependent behavioral effects at early larval stages of an endangered teleost species. Endangered Species Research 2021;44:89-103. R839503 (2021)
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Journal Article Hutton SJ, St Romain SJ, Pedersen EI, Siddiqui S, Chappell PE, White JW, Armbrust KL, Brander SM. Salinity Alters Toxicity of Commonly Used Pesticides in a Model Euryhaline Fish Species (Menidia beryllina). Toxics 2021;9(5):114. R839503 (2021)
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Journal Article Derby AP, Fuller NW, Hartz KE, Segarra A, Connon RE, Brander SM, Lydy MJ. Trophic transfer, bioaccumulation and transcriptomic effects of permethrin in inland silversides, Menidia beryllina, under future climate scenarios. Environmental Pollution 2021;275:116545. R839503 (2021)
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Journal Article Hutton SJ, Siddiqui S, Pedersen EI, Markgraf CY, Segarra A, Hladik ML, Connon RE, Brander SM. Comparative behavioral ecotoxicology of Inland Silverside larvae exposed to pyrethroids across a salinity gradient. Science of The Total Environment 2023;857:159398. R839503 (2023)
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Journal Article St. Romain SJ, Basirico LM, Hutton S, Brander S, Armbrust KL. Influence of Salinity on the Partitioning Behavior of Six Commonly Used Pesticides in Fish Eggs. Environmental Toxicology and Chemistry 2024;43(2):299-306. R839503 (2023)
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Journal Article Hutton SJ, Brander SM. Epigenetics in Aquatic Toxicology. Epigenetics in Aquaculture 2023 Aug 2:301-23. R839503 (2024)
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Journal Article Segarra A, Mauduit F, Amer NR, Biefel F, Hladik ML, Connon RE, Brander SM. Salinity changes the dynamics of pyrethroid toxicity in terms of behavioral effects on newly hatched delta smelt larvae. Toxics. 2021;9(2):40. R839503 (2021)
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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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