Grantee Research Project Results

Exposure Assessment of Children and Metals in Mining Waste: Composition, Environmental Transport, and Exposure Patterns

EPA Grant Number: R831725C002
Subproject: this is subproject number 002 , established and managed by the Center Director under grant R831725
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
Center: Health Effects Institute (2015 - 2020)
Center Director: Greenbaum, Daniel S.
Title: Exposure Assessment of Children and Metals in Mining Waste: Composition, Environmental Transport, and Exposure Patterns
Investigators: Shine, James P. , Spengler, John D.
Institution: Harvard University
EPA Project Officer: Callan, Richard
Project Period: June 1, 2004 through May 31, 2009 (Extended to May 31, 2011)
RFA: Centers for Children's Environmental Health and Disease Prevention Research (2003) RFA Text | Recipients Lists
Research Category: Children's Health , Human Health

Objective:

The objectives of this research project are to: (1) assess the utility of size fractionation and sequential extraction studies for characterizing chat; (2) conduct a nested case-control study of the determinants of high versus low burdens of metals amongst children participating in Project 1 (R831725C001); and (3) produce standardized homogenized chat for Projects 3 and 4 (R831725C003 and R831725C004, respectively).

Publications and Presentations:

Publications have been submitted on this subproject: View all 6 publications for this subproject | View all 63 publications for this center

Supplemental Keywords:

children, Native American, tribal, mixtures, lead, PBPK, community, Superfund, intervention, environmental management,, RFA, Health, Scientific Discipline, ENVIRONMENTAL MANAGEMENT, INTERNATIONAL COOPERATION, Waste, Health Risk Assessment, Hazardous Waste, Children's Health, Hazardous, Risk Assessment, community-based intervention, epidemiology, fate and transport , developmental toxicity, Human Health Risk Assessment, neurodevelopmental toxicity, children's environmental health, biological markers, mining waste, metal wastes, metals, human health risk, metal contamination

Progress and Final Reports:

Main Center Abstract and Reports:

R831725 Health Effects Institute (2015 - 2020)

Subprojects under this Center: (EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
R831725C001 Metals, Nutrition, and Stress in Child Development
R831725C002 Exposure Assessment of Children and Metals in Mining Waste: Composition, Environmental Transport, and Exposure Patterns
R831725C003 Manganese, Iron, Cadmium, and Lead Transport from the Environment to Critical Organs During Gestation and Early Development in a Rat Model
R831725C004 Metals Neurotoxicity Research Project

Top of Page

The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.