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Grantee Research Project Results

Publications submitted after final report Details for Grant Number R831952

Air Pollution Role in Hypertension and Heart Attacks

RFA: The Role of Air Pollutants in Cardiovascular Disease (2003)

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Abstract (1)
Journal Article (4)
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Reference Type Reference Title Journal Author Citation Progress Report Year (Date Added to Report) Document Sources
Abstract Direct and acute cardiotoxicity of ultrafine air pollutants. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Wold LE, Simkhovich BZ, Nordlie MA, Kleinman MT, Sioutas C, Kloner RA Wold LE, Simkhovich BZ, Nordlie MA, Kleinman MT, Sioutas C, Kloner RA. Direct and acute cardiotoxicity of ultrafine air pollutants. Journal of the American College of Cardiology 2006;47(4 Suppl 1):84A. R831952 (Final) (01/23/12)
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Journal Article Inhaled ultrafine particulate matter affects CNS inflammatory processes and may act via MAP kinase signaling pathways. TOXICOLOGY LETTERS Kleinman MT, Araujo JA, Nel A, Sioutas C, Campbell A, Cong PQ, Li H, Bondy SC Kleinman MT, Araujo JA, Nel A, Sioutas C, Campbell A, Cong PQ, Li H, Bondy SC. Inhaled ultrafine particulate matter affects CNS inflammatory processes and may act via MAP kinase signaling pathways. Toxicology Letters 2008;178(2):127-130. R831952 (Final) (10/05/18)
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Journal Article Air pollution and cardiovascular injury epidemiology, toxicology, and mechanisms. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Simkhovich BZ, Kleinman MT, Kloner RA Simkhovich BZ, Kleinman MT, Kloner RA. Air pollution and cardiovascular injury epidemiology, toxicology, and mechanisms. Journal of the American College of Cardiology 2008;52(9):719-726. R831952 (Final) (01/23/12)
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Journal Article Chronically inhaled ambient particles cause cardiac inflammation in normal, diseased, and elderly rat hearts. AIR QUALITY ATMOSPHERE AND HEALTH Simkhovich BZ, Kleinman MT, Willet P, Gookin G, Salazar K, Keebaugh A, Kloner RA Simkhovich BZ, Kleinman MT, Willet P, Gookin G, Salazar K, Keebaugh A, Kloner RA. Chronically inhaled ambient particles cause cardiac inflammation in normal, diseased, and elderly rat hearts. Air Quality Atmosphere and Health 2011;4(1):27-36. R831952 (Final) (01/23/12)
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Journal Article Chronic exposure to ambient particulate matter alters cardiac gene expression patterns and markers of oxidative stress in rats. AIR QUALITY ATMOSPHERE AND HEALTH Simkhovich BZ, Kleinman MT, Mehrian-Shai R, Hsu YH, Meacher D, Gookin G, Kinnon MM, Salazar K, Willet P, Feng G, Lin SM, Kloner RA Simkhovich BZ, Kleinman MT, Mehrian-Shai R, Hsu YH, Meacher D, Gookin G, Kinnon MM, Salazar K, Willet P, Feng G, Lin SM, Kloner RA. Chronic exposure to ambient particulate matter alters cardiac gene expression patterns and markers of oxidative stress in rats. Air Quality Atmosphere and Health 2011;4(1):15-25. R831952 (Final) (01/23/12)
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Presentation Inflammatory and oxidant/antioxidant status of 22-month-old rats exposed to PM2.5 in Los Angeles, CA. None Hamade A, Sioutas C, Froines J, Kloner R, Kleinman M Hamade A, Sioutas C, Froines J, Kloner R, Kleinman M. Inflammatory and oxidant/antioxidant status of 22-month-old rats exposed to PM2.5 in Los Angeles, CA. Presented at the 24th Annual American Association for Aerosol Research Conference, Los Angeles, CA, October 17-21, 2005. R831952 (Final) (01/23/12)
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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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