trans-1,2-Dichloroethylene

CASRN 156-60-5

Health Hazard Assessments for Effects Other than Cancer


Reference Dose for Oral Exposure (RfD) (PDF) (22 pp, 215 K) last updated: 09/30/2010

RfD (mg/kg-day) System Basis PoD Composite UF Confidence
2 x10-2 Immune Decrease in number of antibody forming cells (AFCs) against sheep red blood cells (sRBCs) in male mice BMDL1SD : 65.0
mg/kg-day
3000 Low

Reference Concentration for Inhalation Exposure (RfC) (PDF) (22 pp, 215 K) last updated: 09/30/2010
Information reviewed but value not estimated.

Cancer Assessment


Weight of Evidence for Cancer (PDF) (22 pp, 215 K) last updated: 09/30/2010

WOE Characterization Framework for WOE Characterization
Inadequate information to assess carcinogenic potential Guidelines for Carcinogen Risk Assessment (US EPA, 2005)
Basis:
  • Under the Guidelines for Carcinogen Risk Assessment (U.S. EPA, 2005a), there is "inadequate information to assess the carcinogenic potential" of trans-1,2-DCE.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (22 pp, 215 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (22 pp, 215 K)

Not assessed under the IRIS Program.

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