Science Inventory

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Franklin, J., B. Chorley, V. Moser, W. Oshiro, T. Beasley, Kathy Mcdaniel, AND D. Herr. A Genomic Response to Trace Fear Conditioning in the Amygdala of Female Rats After Developmental Exposure to Manganese. SOT Annual Meeting, San Antonio, Texas, March 11 - 15, 2018.

Rooney, J., K. Oshida, N. Vasani, B. Vallanat, N. Ryan, B. Chorley, X. Wang, D. Bell, K. Wu, L. Aleksunes, C. Klaassen, T. Kensler, AND C. Corton. Activation of Nrf2 in the Liver is Associated with Suppression of the Growth Hormone-Regulated STAT5b Transcription Factor. PLOS ONE . Public Library of Science, San Francisco, CA, 13(8):1-30, (2018). https://doi.org/10.1371/journal.pone.0200004

Carswell, G., L. Wehmas, S. Hester, B. Vallanat, J. Chamberlin, C. Wood, B. Chorley, AND B. Bennett. DNA Methylation Alterations Associated with Latent Carcinogenic Activity of Dichloroacetic Acid in Mice. DNA and RNA Methylation - Keystone Symposia, Vancouver, British Columbia, CANADA, January 21 - 26, 2018.

Chorley, B., G. Carswell, G. Nelson, V. Bhat, AND C. Wood. Dose-Response Analysis of Early MicroRNA Alterations Linked to PPAR-alpha Activation. 2018 SOT Annual meeting, San Antonio, TX, March 11 - 15, 2018.

Woolard, E., G. Carswell, Steve Simmons, AND B. Chorley. Establishing a high-throughput, DNA barcode method for assessing CYP-mediated effects on chemical toxicity. SETAC: HTS and Environmental Risk Assessment meeting, Durham, NC, April 16 - 18, 2018.

Woolard, E., G. Carswell, Steve Simmons, AND B. Chorley. Establishing a high-throughput, DNA barcode method for assessing CYP-mediated effects on chemical toxicity. Society for in Vitro Biology, Missouri, St. Louis, June 02 - 06, 2018.

Rooney, J., B. Chorley, N. Kleinstreuer, AND C. Corton. Identification of Androgen Receptor Modulators in a Prostate Cancer Cell Line Microarray Compendium. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 166(1):146-162, (2018). https://doi.org/10.1093/toxsci/kfy187

Cave, M., H. Clair, C. Pinkston, S. Rai, G. Carswell, G. Nelson, M. Pavuk, AND B. Chorley. Liquid Liver Biopsy is Consistent with Steatohepatitis in Polychlorinated Biphenyl Exposed Cohort with Suspected Toxicant Associated Steatohepatitis. Digestive Disease Week, Washington, DC, June 02 - 05, 2018.

Chorley, B. Next generation sequencing applications for microRNA biomarker discovery in toxicological studies. SOT, San Antonio, TX, March 11 - 15, 2018.

Woolard, E., G. Carswell, Steve Simmons, AND B. Chorley. Optimization of DNA Barcode Method to Assess Altered Chemical Toxicity due to CYP-mediated Metabolism. SOT 57th Annual meeting, San Antonio, TX, March 11 - 15, 2018.

Woolard, E., G. Carswell, Steve Simmons, AND B. Chorley. Optimization of DNA barcode method to assess altered chemical toxicity due to CYP-mediated metabolism. North Carolina Academy of Science 2018, NC, Raleigh, March 23 - 24, 2018.

Snow, S., W. Cheng, A. Henriquez, M. Hodge, V. Bass, G. Nelson, G. Carswell, J. Richards, M. Schladweiler, A. Ledbetter, B. Chorley, K. Gowdy, H. Tong, AND U. Kodavanti. Ozone-Induced Vascular Contractility and Pulmonary Injury are Differentially Impacted by Diets Enriched with Coconut Oil, Fish Oil, and Olive Oil. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 163(1):57-69, (2018). https://doi.org/10.1093/toxsci/kfy003

Gant, T., U. Sauer, S. Zhang, B. Chorley, J. Hackermüller, S. Perdichizzi, K. Tollefsen, T. Tralau, B. van Ravenzwaay, C. Yauk, W. Tong, AND A. Poole. A generic Transcriptomics Reporting Framework (TRF) for ‘Omics Data Processing and Analysis. REGULATORY TOXICOLOGY AND PHARMACOLOGY. Elsevier Science Ltd, New York, NY, 12(91):s36-s45, (2017). https://doi.org/10.1016/j.yrtph.2017.11.001

Buesen, R., B. Chorley, B. da Silva Lima, G. Daston, L. Deferme, T. Ebbels, T. Gant, A. Goetz, J. Greally, L. Gribaldo, J. Hackermuller, B. Hubesch, D. Jennen, K. Johnson, J. Kanno, H. Kauffmann, M. Laffont, P. McMullen, R. Meehan, M. Pemberton, S. Perdichizzi, A. Piersma, U. Sauer, K. Schmidt, H. Seitz, K. Sumida, K. Tollefsen, W. Tong, T. Tralau, B. VanRavenzwaay, R. Weber, A. Worth, C. Yauk, AND A. Poole. Applying ‘omics technologies in chemicals risk assessment: Report of an ECETOC workshop. REGULATORY TOXICOLOGY AND PHARMACOLOGY. Elsevier Science Ltd, New York, NY, 91:s3-s13, (2017). https://doi.org/10.1016/j.yrtph.2017.09.002

Woolard, E., G. Carswell, Steve Simmons, M. Babic, AND B. Chorley. Establishing a Cell-based Assay for Assessment of Cellular Metabolism on Chemical Toxicity. GEMS annual fall meeting, RTP, NC, November 07, 2017.

Kauffmann, H., R. Fuchs, B. Chorley, L. Deferme, J. Hackermüller, S. Perdichizzi, A. Poole, U. Sauer, K. Tollefsen, T. Tralau, C. Yauk, B. van Ravenzwaay, H. Kamp, AND T. Ebbels. Framework for the quality assurance of ’omics technologies considering GLP requirements. REGULATORY TOXICOLOGY AND PHARMACOLOGY. Elsevier Science Ltd, New York, NY, 12(91):s27-s35, (2017). https://doi.org/10.1016/j.yrtph.2017.10.007

Rooney, J., N. Ryan, B. Chorley, S. Hester, E. Kenyon, Judy Schmid, BJ George, M. Hughes, Y. Sey, A. Tennant, D. MacMillan, J. Simmons, C. McQueen, A. Pandiri, C. Wood, AND C. Corton. Genomic effects of androstenedione and sex-specific liver cancer susceptibility in mice. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 160(1):15–29, (2017).

Pegram, R., A. Teal, Steve Simmons, T. Ross, J. Campbell, D. DeMarini, AND B. Chorley. Genotoxicity of Brominated Trihalomethanes in Human Bladder Cells. Gordon Research Conference on Drinking Water Disinfection Byproducts, South Hadley, MA, July 30 - August 04, 2017.

Angrish, M., C. McQueen, E. Hubal, M. Bruno, Y. Ge, AND B. Chorley. Mechanistic Toxicity Tests Based on an Adverse Outcome Pathway Network for Hepatic Steatosis. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 159(1):159-169, (2017). https://doi.org/10.1093/toxsci/kfx121

Wehmas, L., A. Deangelo, S. Hester, B. Chorley, G. Carswell, G. Olson, M. George, J. Carter, S. Eldridge, A. Fisher, B. Vallanat, AND C. Wood. Metabolic Disruption Early in Life is Associated With Latent Carcinogenic Activity of Dichloroacetic Acid in Mice. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 159(2):354-365, (2017).

Rooney, J., S. Hiemstra, B. Chorley, B. van de Water, AND C. Corton. Mining a human transcriptome database for chemical modulators of Nrf2. World Congress on alternatives and animal use in the life sciences, Seattle, Washington, August 20 - 24, 2017.

Pegram, R., E. Kenyon, Steve Simmons, D. DeMarini, B. Chorley, A. Teal, AND T. Ross. Molecular Mechanisms by Which Chlorinated Water Causes Bladder Cancer. 48th Annual Meeting of the Environmental Mutagenesis and Genomics Society, Raleigh, North Carolina, September 09 - 13, 2017.

Nelson, G., J. Guynn, AND B. Chorley. Procedure and Key Optimization Strategies for an Automated Capillary Electrophoretic-based Immunoassay Method. Journal of Visualized Experiments . JoVE, Somerville, MA, 127:e55911, (2017). https://doi.org/10.3791/55911

Nelson, G., J. Currier, AND B. Chorley. Procedure and Key Optimization Strategies for an Automated CapillaryElectrophoretic-based Immunoassay Method. JoVE, Somerville, MA, 2017.

Angrish, M., J. Rooney, C. McQueen, AND B. Chorley. Project Number: CSS 12.01 Adverse Outcome Pathway Discovery and Development (AOP-DD)Task Number: Task 1.1d: Putative AOP development related to Fatty Liver Disease (steatosis) Product number: Key Product 1 (AOP knowledgebase development). Society of Toxicology Annual Meeting, Baltimore, MA, March 12 - 16, 2017.