Science Inventory

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Winters, B., M. Angrish, S. Mentese, M. Madden, AND J. Pleil. Gas-Phase Molecular Probe For High Throughput Screening. Gordon Conference Drug Safety, Easton, MA, June 25 - July 01, 2016.

Winters, B., M. Angrish, A. Wallace, J. Pleil, AND M. Madden. In Vitro Toxicity Assessment Technique for Volatile Substances Using Flow-Through System. NC Society of Toxicology, RTP, NC, October 25, 2016.

Stiegel, M., J. Pleil, J. Sobus, AND M. Madden. Inflammatory Cytokines and White Blood Cell Counts Response to Environmental Levels of Diesel Exhaust and Ozone Inhalation Exposures. PLOS ONE . Public Library of Science, San Francisco, CA, 11(4):e0152458, (2016).

Williams, J. AND J. Pleil. Perspective: Crowd-based breath analysis: assessing behavior, activity, exposures, and emotional response of people in groups. Journal of Breath Research. Institute of Physics Publishing, Bristol, Uk, 10(3):032001, (2016).

Pleil, J. QQ-plots for assessing distributions of biomarker measurements and generating defensible summary statistics. Journal of Breath Research. Institute of Physics Publishing, Bristol, Uk, 10(3):035001, (2016).

Winters, B., M. Madden, M. Angrish, M. Stiegel, T. Risby, AND J. Pleil. Standardization of exhaled breath condensate (EBC) collection using a feedback regulated breathing pattern. Society of Toxicology Meeting, New Orleans, LA, March 13 - 17, 2016.

Angrish, M., J. Pleil, M. Stiegel, M. Madden, Ginger Moser, AND D. Herr. Taxonomic applicability of inflammatory cytokines in adverse outcome pathway (AOP) development. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH - PART A: CURRENT ISSUES. Taylor & Francis, Inc., Philadelphia, PA, 79(4):184-196, (2016).

Pleil, J., J. Beauchamp, W. Miekisch, AND W. Funk. Adapting biomarker technologies to adverse outcome pathways (AOPs) research: current thoughts on using in vivo discovery for developing in vitro target methods. Journal of Breath Research. Institute of Physics Publishing, Bristol, Uk, 9(3):039001, (2015).

Pleil, J., M. Angrish, AND M. Madden. Adverse Outcome Pathways (AOPs) in Human Systems Biology: Gas-Phase Probes for Assessing In Vitro Enzyme System Perturbations. PITTCON Confererence & Expo 2015, New Orleans, LA, March 08 - 12, 2015.

Stiegel, M., J. Pleil, J. Sobus, M. Morgan, AND M. Madden. Analysis of inflammatory cytokines in human blood, breath condensate, and urine using a multiplex immunoassay platform. BIOMARKERS. Taylor & Francis, Inc., Philadelphia, PA, 20(1):35-46, (2015).

Pleil, J., M. Angrish, AND M. Madden. Human Exhaled Breath Condensate (EBC) Media: Implementation of Automated Quanterix SIMOA Immunochemistry Instrumentation. IABR Meeting, Vienna, AUSTRIA, September 13 - 16, 2015.

Pleil, J., M. Angrish, AND M. Madden. Immunochemistry for high-throughput screening of human exhaled breath condensate (EBC) media: implementation of automated quanterix SIMOA instrumentation. Journal of Breath Research. Institute of Physics Publishing, Bristol, Uk, 9(4):047108, (2015).

Angrish, M., M. Madden, AND J. Pleil. Inflammatory Cytokines as Preclinical Markers of Adverse Responses to Chemical Stressors. PittCon 2015, New Orleans, LA, March 08 - 12, 2015.

Stiegel, M., J. Pleil, J. Sobus, M. Angriish, AND M. Morgan. Kidney injury biomarkers and urinary creatinine variability in nominally healthy adults. BIOMARKERS. Taylor & Francis, Inc., Philadelphia, PA, 20:436-452, (2015).

Angrish, M., M. Madden, AND J. Pleil. Probe molecules (PrM) approach in adverse outcome pathway (AOP) based high throughput screening (HTS): in vivo discovery for developing in vitro target methods. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 2015(28):551-559, (2015).

Bean, H., J. Pleil, AND J. Hill. Report: New analytical and statistical approaches for interpreting the relationships among environmental stressors and biomarkers. BIOMARKERS. Taylor & Francis, Inc., Philadelphia, PA, 20(1):1-4, (2015).

Pleil, J. The Human Exposome and Systems Biology: Ongoing Empirical Measurement Studies and Biomarker Interpretation. Systems Biology for the Exposome Workshop, Atlanta, GA, May 27, 2015.

Pleil, J. Understanding new “exploratory” biomarker data: a first look at observed concentrations and associated detection limits. BIOMARKERS. Taylor & Francis, Inc., Philadelphia, PA, 20(2):168-169, (2015).

Funk, W., J. Pleil, D. Sauter, T. McDade, AND J. Holl. Use of Dried Blood Spots for Estimating Children?s Exposures to Heavy Metals in Epidemiological Research. Journal of Environmental & Analytical Toxicology. OMICS Publishing Group, LOS ANGELES , CA, 7:002, (2015).

Sobus, J., Rob Dewoskin, C. Tan, J. Pleil, M. Philips, BJ George, K. Christensen, D. Schreinemachers, M. Williams, E. Hubal, AND S. Edwards. Uses of NHANES biomarker data for chemical risk assessment: Trends, challenges and opportunities. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 123(10):919-927, (2015).

Sobus, J. AND J. Pleil. Using Spot Biomarker Data to Inform Chronic Exposure and Health Risk. 2015 ISES Annual Meeting, Henderson, NV, October 18 - 23, 2015.

Winters, B., M. Madden, M. Angrish, M. Stiegel, T. Risby, AND J. Pleil. Variability of exhaled breath condensate (EBC) volume and pH using a feedback regulated breathing pattern. Internat. Assoc. Breath Res, Vienna, AUSTRIA, September 14 - 16, 2015.

Lu, S., J. Sobus, G. Sallsten, M. Albin, J. Pleil, A. Gudmundsson, M. Madden, B. Strandberg, A. Wierzbicka, AND S. Rappaport. Are Urinary PAHs Biomarkers of Controlled Exposure to Diesel Exhaust? BIOMARKERS. Taylor & Francis, Inc., Philadelphia, PA, 19(4):332-9, (2014).

Stevens, T., M. Case, A. Rappold, J. Pleil, D. Diaz-Sanchez, W. Cascio, R. Devlin, AND M. Madden. Cardiovascular effects of diesel exhaust and ozone in a multi-pollutant context. Presented at Society of Toxicology, Phoenix, AZ, March 23 - 27, 2014.

Stiegel, M., J. Pleil, J. Sobus, AND M. Madden. Combining data visualization and statistical approaches for interpreting measurements and meta-data: Integrating heatmaps, variable clustering, and mixed regression models. Presented at American Chemical Society Meeting, San Francisco, CA, August 10 - 14, 2014.