Science Inventory

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Villeneuve, D., B. Blackwell, C. Blanksma, J. Cavallin, W. Cheng, R. Conolly, K. Conrow, D. Feifarek, L. Heinis, K. Jensen, M. Kahl, R. Milsk, S. Poole, E. Randolph, T. Saari, K. Watanabe, AND G. Ankley. Case Study in 21st-Century Ecotoxicology: Using In Vitro Aromatase Inhibition Data to Predict Reproductive Outcomes in Fish In Vivo. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 42(1):100-116, (2023). https://doi.org/10.1002/etc.5504

Villeneuve, Dan, B. Blackwell, J. Cavallin, W. Cheng, R. Conolly, D. Feifarek, K. Jensen, M. Kahl, R. Milsk, S. Poole, E. Randolph, T. Saari, AND G. Ankley. Case study in 21st century ecotoxicology: Using in vitro aromatase inhibition data to predict short term in vivo responses in adult female fish. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 40(4):1155-1170, (2021). https://doi.org/10.1002/etc.4968

Hines, D., R. Conolly, AND A. Jarabek. A quantitative approach for integrating mechanistic data across human health and ecological endpoints to inform risk assessment using Aggregate Exposure Pathway and Adverse Outcome Pathway networks. Society of Toxicology, Baltimore, Maryland, March 10 - 14, 2019.

Hines, D., R. Conolly, AND A. Jarabek. A quantitative source-to-outcome case study to demonstrate the integration of human health and ecological endpoints using the Aggregate Exposure Pathway and Adverse Outcome Pathway frameworks. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 53(8):11002-11012, (2019). https://doi.org/10.1021/acs.est.9b04639

Perkins, E., R. Ashauer, L. Burgoon, R. Conolly, B. Landesmann, C. Mackay, C. Murphy, N. Pollesch, J. Wheeler, A. Zupanic, AND S. Scholz. Building and applying quantitative adverse outcome pathway models for chemical hazard and risk assessment. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 38(9):1850-1865, (2019). https://doi.org/10.1002/etc.4505

Conolly, R. AND Tim Shafer. Computational Modeling of an In Vitro Neural Network – Microelectrode Assay for Neurotoxicity Screening. SOT 2019 Annual Meeting, Baltimore, Maryland, March 10 - 14, 2019.

Zhang, Q., W. Caudle, J. Pi, S. Bhattacharya, M. Andersen, N. Kaminski, AND R. Conolly. Embracing Systems Toxicology at Single-Cell Resolution. Current Opinion in Toxicology. Elsevier BV, AMSTERDAM, Netherlands, 16:49-57, (2019). https://doi.org/10.1016/j.cotox.2019.04.003

Martin, W., A. Tennant, R. Conolly, K. Prince, J. Stevens, D. DeMarini, B. Martin, L. Thompson, Ian Gilmour, W. Cascio, M. Hays, M. Hazari, S. Padilla, AND A. Farraj. High-Throughput Video Processing to Score Heart Rate Responses to Xenobiotics in Wild-type Embryonic Zebrafish per imaging field. Scientific Reports. Nature Publishing Group, London, Uk, 9(1):145, (2019). https://doi.org/10.1038/s41598-018-35949-5

Hines, D., R. Conolly, AND Ann Jarabek. Modeling mechanistic processes from source to outcome to support evidence integration and inform risk assessment. NAS Evidence Integration Workshop, Washington, DC, June 03 - 04, 2019.

Hill, T., M. Marikar, AND R. Conolly. Use of a PBPK-Quantitative Adverse Outcome Pathway Model to Resolve the Species Specificity of Lung Carcinogens. 58th Annual Meeting Society of Toxciology, Baltimore, Maryland, March 10 - 14, 2019.

Hines, D., S. Edwards, R. Conolly, AND A. Jarabek. A Case Study Application of the Aggregate Exposure Pathway (AEP) and Adverse Outcome Pathway (AOP) Frameworks to Facilitate the Integration of Human Health and Ecological End Points for Cumulative Risk Assessment (CRA). ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 52(2):839-849, (2018).

Hines, D., R. Conolly, AND A. Jarabek. A mechanistic approach for source-to-outcome risk assessment across human health and ecological endpoints using the Aggregate Exposure Pathway (AEP) and Adverse Outcome Pathway (AOP) frameworks. SOT RASS, MD, Annapolis, November 14, 2018.

Conolly, R. AND M. Hecker. Advancing the Adverse Outcome Pathway Framework – An International Horizon Scanning Approach. SOT Annual Meeting, San Antonio, Texas, March 11 - 15, 2018.

Martin, W., A. Tennant, R. Conolly, J. Stevens, D. DeMarini, Ian Gilmour, W. Cascio, M. Hays, B. Martin, L. Thompson, M. Hazari, S. Padilla, AND A. Farraj. An Automated Heart Rate Detection Platform in Wild-Type Zebrafish for Cardiotoxicity Screening of Fine Particulate Matter Air Pollution. Society of Toxicology Annual Meeting, San Antonio, Texas, March 11 - 16, 2018.

Hines, D., R. Conolly, AND A. Jarabek. An application of Aggregate Exposure Pathway and Adverse Outcome Pathway frameworks to facilitate the integration of human health and ecological endpoints for Cumulative Risk Assessment. RTI, Durham, North Carolina, October 30, 2018.

Hines, D., S. Edwards, R. Conolly, AND A. Jarabek. Application of the Aggregate Exposure Pathway and Adverse Outcome Pathway frameworks to advance cumulative risk assessment by integrating human health and ecological endpoints. Society of Toxicology, san antonio, Tx, March 11 - 15, 2018.

Snow, S., W. Cheng, A. Henriquez, A. Farraj, M. Hazari, R. Conolly, AND U. Kodavanti. Bittersweet: Real-Time, Dynamic Changes in Blood Glucose Levels during an Acute Ozone Exposure in Rats. Society of Toxicology, San Antonio, TX, March 11 - 15, 2018.

Zhang, Q., J. Li, A. Middleton, S. Bhattacharya, AND R. Conolly. Bridging the Data Gap from in vitro Toxicity Testing to Chemical Safety Assessment through Computational Modeling. Frontiers in Public Health. Frontiers, Lausanne, Switzerland, 6:261, (2018). https://doi.org/10.3389/fpubh.2018.00261

Cheng, W., K. Duncan, Andy Ghio, C. Ward-Caviness, E. Karoly, D. Diaz-Sanchez, R. Conolly, AND R. Devlin. Changes in metabolites present in lung-lining fluid following exposure of humans to ozone. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 163(2):430-439, (2018). https://doi.org/10.1093/toxsci/kfy043

Hill, T. AND R. Conolly. Development of a Novel Quantitative Adverse Outcome Pathway Predictive Model for Lung Cancer. SETAC Europe 28th Annual Meeting, Rome, Rome, ITALY, May 13 - 17, 2018.

Hill, T. AND R. Conolly. Post-hoc Development of a Quantitative Adverse Outcome Pathway Prediction Model for Lung Cancer. NC Chapter SOT, Research Triangle Park, North Carolina, October 15, 2018.

Conolly, R. A Quantitative Adverse Outcome Pathway for Ecotoxicity: Modeling Reproductive Adversity in Fathead Minnows. 3rd International Conference on Toxicity Testing Alternatives & Translational Toxicology, Nanjing, China, CHINA, July 09 - 12, 2017.

Hines, D., S. Edwards, R. Conolly, AND A. Jarabek. A case study to illustrate the utility of the Aggregate Exposure Pathway and Adverse Outcome Pathway frameworks for integrating human health and ecological data into cumulative risk assessment. International Society of Exposure Science Annual Meeting, Research Triangle Park, NC, October 15 - 19, 2017.

Hines, D., S. Edwards, R. Conolly, AND A. Jarabek. An application of the Aggregate Exposure Pathway (AEP) and Adverse Outcome Pathway (AOP) frameworks to mechanistically integrate data sources across multiple species into cumulative risk assessment (CRA). International Symposium on Systematic Review and Meta-Analysis of Laboratory Animal Studies, Durham, North Carolina, August 24 - 25, 2017.

Hines, D., S. Edwards, R. Conolly, AND A. Jarabek. Cross-species integration of human health and ecological endpoints into risk assessment using the Aggregate Exposure Pathway and Adverse Outcome Pathway frameworks. Society of Toxicology, Baltimore, MD, March 12 - 16, 2017.