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Records 1 to 25 of 67 records from author Dustin Kapraun

2024
Truong, K., D. Kapraun, S. Davidson-Fritz, J. Wambaugh, S. Degitz, J. Olker, M. Hornung, R. Judson, AND K. Friedman. In Vitro-In Vivo Extrapolation of Thyroid-Related Endpoints with Higher Throughput Pregnancy PBPK Modeling. Quantitative Systems Pharmacology (QSP) Summit Cambridge 2024, Cambridge, MA, May 01, 2024. https://doi.org/10.23645/epacomptox.25765788
2023
Rowan, E., R. Hines, S. Vulimiri, B. Wetmore, C. Brinkerhoff, A. Jarabek, D. Kapraun, E. Kenyon, C. Ring, J. Wambaugh, AND R. Sayre. Constructing An Enzyme Ontogeny Database to Improve Characterization of Toxicokinetic Lifestage Differences (Poster). Society of Toxicology, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.22266274
Rowan, E., R. Hines, Suryanarayana Vulimiri, B. Wetmore, C. Brinkerhoff, A. Jarabek, D. Kapraun, E. Kenyon, C. Ring, J. Wambaugh, AND R. Sayre. Constructing an Enzyme Ontogeny Database to Improve Characterization of Toxicokinetic Lifestage Differences. NC Symposium on Life/Data Sciences, Precision Medicine/Environmental Health, RTP, NC, May 08, 2023. https://doi.org/10.23645/epacomptox.22266274
Weitekamp, C., D. Kapraun, C. Chiang, L. Carlson, K. Christensen, AND G. Lehmann. Evaluating the relative responsiveness of health effects to exposure to polychlorinated biphenyl (PCB) mixtures in mammalian model systems. SOT, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.22263919
Zurlinden, T., D. Kapraun, T. Blessinger, AND P. Schlosser. Implementing Probabilistic Methods in US EPA Human Health Assessments. Probabilistic Risk Assessment Workshop: From Cellular Perturbation to Hazard, Durham, NC, July 04 - 06, 2023.
Schlosser, P., D. Kapraun, AND M. Dzierlenga. Pharmacokinetics of PFAS & Male-Female Differences. SRA RT Lightning Talks (Webinar), Durham, NC, September 13, 2023.
Kapraun, D. Physiologically Based Pharmacokinetic Models and Applications in Chemical Risk Assessments - Haverford College Invited Presentation. Math 382: Mathematical Modeling and Differential Equations (Guest Lecture), Haverford, PA, October 04, 2023.
2022
Kapraun, D., T. Zurlinden, M. Verner, C. Chiang, M. Dzierlenga, L. Carlson, P. Schlosser, AND G. Lehmann. A Generic Pharmacokinetic Model for Quantifying Mother-to-Offspring Transfer of Lipophilic Persistent Environmental Chemicals. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 189(2):155-174, (2022). https://doi.org/10.1093/toxsci/kfac084
Bernstein, A., B. Prasad, P. Schlosser, AND D. Kapraun. Accelerating QA review of PBPK models: A template approach to model implementation. SRA Dose Response Specialty Group Presentation, Durham, NC, September 13, 2022.
Zurlinden, T., P. Schlosser, D. Kapraun, M. Dzierlenga, A. Bernstein, AND V. Morozov. Data Integration and Pharmacokinetic Model Testing for Selected PFAS. Considerations of Development of DOD Exposure Limits for Current PFAS Compounds, NA, NC, July 21, 2022.
Zurlinden, T., M. Dzierlenga, D. Kapraun, B. Prasad, A. Bernstein, P. Schlosser, AND V. Morozov. Determination of species- and sex-dependent PFAS pharmacokinetics (PK) through Bayesian hierarchical modeling. Society of Toxicology 2022 Annual Meeting, San Diego, CA, March 27 - 31, 2022.
Groff, L., J. Grossman, A. Kruve, J. Minucci, C. Lowe, J. McCord, D. Kapraun, K. Phillips, Tom Purucker, A. Chao, C. Ring, A. Williams, AND J. Sobus. Estimating Uncertainty of Predicted Chemical Concentrations via Quantitative Non-Targeted Analysis. Fall ACS, Chicago, IL, August 21 - 25, 2022. https://doi.org/10.23645/epacomptox.19763524
Groff, L., J. Grossman, A. Kruve, J. Minucci, C. Lowe, J. McCord, D. Kapraun, K. Phillips, Tom Purucker, A. Chao, C. Ring, A. Williams, AND J. Sobus. Estimating Uncertainty of Predicted Chemical Concentrations via Quantitative Non-Targeted Analysis (SETAC NTA). SETAC NTA Focused Topic Meeting, Durham, NC, May 22 - 26, 2022. https://doi.org/10.23645/epacomptox.20503272
Schacht, C., A. Meade, A. Bernstein, B. Prasad, P. Schlosser, H. Tran, AND D. Kapraun. Evaluating Impacts of Physiological Variability on Human Equivalent Doses Using PBPK Models - SEARCDE 2022 Presentation. Southeastern-Atlantic Regional Conference on Differential Equations, Raleigh, NC, November 12 - 13, 2022.
Schacht, C., A. Meade, A. Bernstein, B. Prasad, P. Schlosser, H. Tran, AND D. Kapraun. Evaluating impacts of human physiological variability on distributions of internal dose metrics. Joint Mathematics Meetings, Seattle, WA, January 05 - 08, 2022.
Schacht, C., A. Meade, A. Bernstein, B. Prasad, P. Schlosser, H. Tran, AND D. Kapraun. Evaluating impacts of physiological variability on human equivalent doses using PBPK models. ISop QSP Virtual Student Symposium 2022, NA, NC, May 11, 2022.
Kapraun, D., M. Sfeir, R. Pearce, S. Davidson, A. Lumen, A. Dallmann, R. Judson, AND J. Wambaugh. Evaluation of a rapid, generic human gestational dose model (Manuscript). REPRODUCTIVE TOXICOLOGY. Elsevier Science Ltd, New York, NY, 113:172-188, (2022). https://doi.org/10.1016/j.reprotox.2022.09.004
Kapraun, D. Generic Pharmacokinetic Models for Mother-to-Offspring Transfer of Chemicals - Presentation for SOT RASS December 2022. Webinar for Risk Assessment Specialty Section (RASS) of Society of Toxicology (SOT), NA, NC, December 14, 2022.
Dzierlenga, M., P. Schlosser, D. Kapraun, T. Zurlinden, V. Morozov, AND A. Bernstein. PFAS PK Challenges. Considerations on Development of DOD Exposure Limits for Current PFAS Compounds (Virtual), DC, DC, July 21, 2022.
Kapraun, D. Physiologically Based Pharmacokinetic Models and Applications in Chemical Risk Assessments - SEARCDE 2022 Presentation. Southeastern-Atlantic Regional Conference on Differential Equations, Raleigh, NC, November 12 - 13, 2022.
Schlosser, P., D. Kapraun, T. Zurlinden, AND M. Verner. Predicted Accumulation of Persistent Compounds Across Generations. 2022 SOT Annual Meeting, San Diego, CA, March 27 - 31, 2022.
Kapraun, D. Quality Assurance Protocols for Physiologically Based Pharmacokinetic (PBPK) Models. Society of Toxicology Annual Meeting, San Diego (and online), CA, March 27 - 31, 2022.
Kapraun, D. Quality Assurance for Physiologically Based Pharmacokinetic (PBPK) Models - PCRM NURA Training Presentation. Human In, Human Out: Using Primary and Population Data for PBPK Analyses, NA, NC, November 17, 2022.
Kapraun, D., P. Schlosser, T. Zurlinden, A. Jarabek, C. Brinkerhoff, AND J. Zhao. RATE Module HSR306 - Quantitative Methods and Models: Dosimetry Adjustments and Pharmacokinetic Concepts. Taiwan EPA RATE Presentations, NA, TAIWAN, PROVINCE OF CHINA, July 13 - 15, 2022.
Prasad, B., A. Bernstein, D. Kapraun, AND P. Schlosser. The many ways to describe gas uptake: An extension of a PBPK model template to VOCs. Society of Toxicology 61st Annual Meeting and ToxExpo, San Diego, CA, March 27 - 31, 2022.