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Records 1 to
25
of 71 records from author Shaun Mccullough
2024
Huber, E., O. Rice, L. Dailey, J. Murray, AND S. McCullough. Common Liquid Application Dosing Conditions Alter Toxicity Testing Endpoints in Air-Liquid Interface Primary Human Bronchial Epithelial Cultures. Society of Toxicology, Salt Lake City, UT, March 10 - 14, 2024.
Mallek, N., E. Martin, L. Dailey, AND S. McCullough. Liquid Application Dosing Alters the Physiology of Air-Liquid Interface (ALI) Primary Human Bronchial Epithelial Cell/Lung Fibroblast Co-Cultures and In Vitro Testing Relevant Endpoints. Frontiers in Toxicology. Frontiers, Lausanne, Switzerland, 5:1264331, (2023). https://doi.org/10.3389/ftox.2023.1264331
Pulczinski, J., A. Rappold, R. Devlin, M. Case, A. Ghio, AND S. McCullough. Sex modifies the pulmonary and inflammatory responses to ozone and nitrogen dioxide: results from a controlled human exposure trial. Society of Toxicology 63rd Annual Meting and ToxExp, Salt Lake City, UT, March 10 - 14, 2024.
2023
McCullough, S. Considering Complexities: Impacts of Multicellularity, Inter-Individual Variability, and Dosing on Modeling Inhaled Chemical Exposure Effects In Vitro. Research Triangle Institute International, Research Triangle Park, NC, February 16, 2023.
McCullough, S. Considering Complexities: Impacts of Multicellularity, Inter-Individual Variability, and Dosing on Modeling Inhaled Chemical Exposure Effects In Vitro#. Research Institute for Fragrance Materials Respiratory Working Group, Virtual, NC, February 15, 2023.
Huber, E., O. Rice, L. Dailey, AND S. McCullough. Finding the Balance: Minimizing the Impact of Solvent and Volume on Toxicity Testing Endpoints During Liquid Application Dosing on Air-Liquid Interface Bronchial Epithelial Cultures. Society of Toxicology Annual Meeting, Nashville, TN, March 19 - 23, 2023.
Hickman, E., A. Simmons, M. Wheeler, S. Auerbach, S. McCullough, AND J. Rager. Interindividual Variability Assessments through Benchmark Dose-Response Modeling of Primary Human Bronchial Epithelial-Fibroblast Co-Culture Responses to Acrolein. Society of Toxicology Annual Meeting, Nashville, TN, March 19 - 23, 2023.
McCullough, S. Non-Commercial Models for the Evaluation of Inhalable Materials In Vitro. American Cleaning Institute Workshop to Examine New Test Methods for Cleaning Product Safety, Arlington, VA, March 02, 2023.
Mallek, N. AND S. McCullough. Wood Smoke Particulate Exposure Induces NRF2-mediated Intercellular Signaling Between Fibroblasts and Epithelial Cells in a Lung Coculture Model. Society of Toxicology Annual Meeting, Nashville, TN, March 19 - 23, 2023.
2022
Vitucci, E. AND S. McCullough. A Novel In Vitro Model of the Alveolar Capillary Region: Bridging the Gap Between Inhalation Toxicology and Cardiovascular Disease. Society of Toxicology Annual Meeting, San Diego, California, March 27 - 31, 2022.
McCullough, S. A data-driven assessment of the need for harmonization as a path forward for increasing confidence in in vitro air-liquid interface systems for chemical testing. Society of Toxicology Annual Meeting, San Diego, CA, March 27 - 31, 2022.
Mallek, N., E. Martin, AND S. McCullough. Air-Liquid Interface Re-Submersion Alternatively Regulates Stress-Responsive Signaling, Enhances Cytokine Secretion, and Increases Barrier Permeability in Primary Human Bronchial Epithelial Cells. Society of Toxicology Annual Meeting, San Diego, California, March 27 - 31, 2022.
Simmons, A., N. Mallek, E. Aungst, AND S. McCullough. Characterizing intra-human variation in common toxicity endpoints in differentiated primary bronchial epithelial cell cultures. Society of Toxicology Annual Meeting, San Diego, California, March 27 - 31, 2022.
McCullough, S. Development and Deployment of In Vitro NAMs for Inhaled Chemical Testing. Duke University ENV819 Course, Durham, North Carolina, March 15, 2022.
McCullough, S. From Concepts to Cultures: Building a Solid Foundation for IVIVE and the Sustainability of In Vitro Approaches to Inhaled Chemical Testing. Society of Toxicology In Vitro and Alternative Methods Specialty Section Webinar, Virtual, Virtual, January 27, 2022.
McCullough, S. Impacts of Inter-Individual Variability on Differentiated Primary Cell-Based In Vitro Models for Inhaled Chemical Safety Evaluation. National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) Population Variability Webinar 3, Virtual, NC, October 07, 2022.
McCullough, S. Model Complexities: Impacts of Inter-Individual Variability and Multicellularity on Modeling Inhaled Chemical Exposures In Vitro. Columbia University seminar, New York, NY, November 16, 2022.
Bowers, E., E. Martin, A. Jarabek, D. Morgan, H. Smith, L. Dailey, E. Aungst, D. Diaz-Sanchez, AND S. McCullough. Ozone responsive gene expression as a model for describing repeat exposure response trajectories and inter-individual toxicodynamic variability in vitro. Society of Toxicology Annual Meeting, San Diego, California, March 27 - 31, 2022.
Bowers, E., E. Martin, A. Jarabek, D. Morgan, H. Smith, L. Dailey, E. Aungst, D. Diaz-Sanchez, AND S. McCullough. Ozone responsive gene expression as a model for describing repeat exposure response trajectories and interindividual toxicodynamic variability in vitro. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 185(1):38-49, (2022). https://doi.org/10.1093/toxsci/kfab128
McCullough, S. Particulate Toxicology in the 21st Century: Organotypic Models Reveal Trans-Epithelial Effects of Particulates in the Respiratory Tract. International Particulate Toxicology Conference, Santa Fe, NM, August 28 - 31, 2022.
2021
Mallek, N., E. Martin, L. Dailey, AND S. McCullough. Air-Liquid Interface Re-Submersion Alternatively Regulates Stress-Responsive Signaling, Enhances Cytokine Secretion, and Increases Barrier Permeability in Primary Human Bronchial Epithelial Cells#. 10th Annual Meeting of the American Society of Cellular and Computational Toxicology (ASCCT), Virtual, NC, October 12 - 14, 2021.
Dailey, L. AND S. McCullough. Culture and Differentiation of Primary Human Tracheobronchial Epithelial Cells Using STEMCELL Technologies Pneumacult Media. Nature Publishing Group, London, Uk, 2021. https://doi.org/10.21203/rs.3.pex-1674/v1
Mallek, N. AND S. McCullough. Culture of IMR90 Cells in Advanced MEM with Reduced Serum. Nature Publishing Group, London, Uk, 2021. https://doi.org/10.21203/rs.3.pex-1673/v1
Dailey, L. AND S. McCullough. Culture of Primary Human Tracheobronchial Epithelial Cells. Nature Publishing Group, London, Uk, 2021. https://doi.org/10.21203/rs.3.pex-1379/v1
McCullough, S. Development and Harmonization of Organotypic/Co-Culture Models and Assays to Improve Throughput and In Vivo Relevance in Inhaled Chemical Testing. CSS Board of Scientific Counselors, Virtual, Virtual, February 02 - 05, 2021.