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Considering Complexities: Impacts of Multicellularity, Inter-Individual Variability, and Dosing on Modeling Inhaled Chemical Exposure Effects In Vitro
Citation:
McCullough, S. Considering Complexities: Impacts of Multicellularity, Inter-Individual Variability, and Dosing on Modeling Inhaled Chemical Exposure Effects In Vitro. Research Triangle Institute International, Research Triangle Park, NC, February 16, 2023.
Impact/Purpose:
Presentation on data regarding the impact of multi-cellular co-culture, inter-individual variability, and dosing methods on in vitro systems used for the assessment of inhalable materials.
Description:
•Advances in molecular biology and biotechnology will pave the way to major improvements in the evaluation of health risks. •“These advances would make toxicity testing quicker, less expensive, and more directly relevant to human exposures. They could also reduce the need for animal testing by substituting more laboratory tests based on human cells”