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Children&rsquo;s health can be significantly impacted by direct exposure to different chemical hazards in the physical environment. Previous research has linked biological factors to an increase in vulnerability, but there are other factors that may affect exposures and health ou...

The Puerto Rico&rsquo;s Ca&ntilde;o Martin Pe&ntilde;a (CMP), made of eight environmental-justice (EJ) communities, is experiencing detrimental environmental conditions due to the non-existence or inadequate sanitary sewer and storm sewer systems and the environmental degradation...

Inhalation of smoke from burning of waste materials on military bases is associated with increased incidences of cardiopulmonary diseases. This study examined the respiratory and inflammatory effects of acute inhalation exposures in mice to smoke generated by military burn pit-re...

There is growing awareness that indoor molds/fungi may be connected to such conditions as asthma, allergies, hemorrhaging, chronic rhinosinusitis, memory loss, and a symptom complex called sick-building-syndrome. In addition, molds cause frequently fatal nosocomical infections. ...

Objective(s) This study explored the feasibility, acceptability, preliminary impact, and functionality of two risk reduction mobile application (app) interventions on asthma outcomes as compared to a control arm during wildfire season. Design Three-arm, 8-week randomized clinic...

Abstract: It is proposed that the mechanistic basis for non-neoplastic lung injury with cigarette smoking is a disruption of iron homeostasis in cells after exposure to cigarette smoke particle (CSP). Following the complexation and sequestration of intracellular iron by CSP, the ...

Thist is a summary of research conducted by the Environmental Protection Agency (EPA) )to develop a full-scale emissions test method that characterizes the application and post-application emissions from spray polyurethane foam (SPF) insulation The primary objectives of the resea...

Freight movement and the transport sector significantly impact air quality, especially at the local scale.&nbsp; In many cities throughout the world, freight emissions from truck, rail and ship traffic at ports can contribute large amounts of air pollution, including particulate ...

Although the health benefits of swimming are well-documented, health effects such as asthma and bladder cancer are linked to disinfection by-products (DBPs) in pool water.&nbsp; DBPs are formed from the reaction of disinfectants such as chlorine (Cl) or bromine (Br) with organics...

The Puerto Rico&rsquo;s Ca&ntilde;o Martin Pe&ntilde;a (CMP), made of eight environmental-justice (EJ) communities, is experiencing detrimental environmental conditions due to the non-existence or inadequate sanitary sewer and storm sewer systems and the environmental degradation...

Project Abstract: Problem: The Puerto Rico&rsquo;s Ca&ntilde;o Martin Pe&ntilde;a (CMP), made of eight environmental-justice (EJ) communities, is experiencing detrimental environmental conditions due to the non-existence or inadequate sanitary sewer and storm sewer systems and th...

The goal of this case study was to examine whether the Environmental Relative Moldiness Index (ERMI) scale created for United States (U.S.) homes was applicable in the assessment of mold contamination for Australian homes. Settled-dust samples were collected in southeastern Aust...

OBJECTIVE To quantify dectin-1 expression in bronchoalveolar lavage fluid (BALF), create polyclonal antibodies against equine dectin-1 and localize it in tissues, and quantify fungal exposure in pastured and stabled asthmatic and nonasthmatic horses. SAMPLES BALF samples from 6...

Air pollution emissions from the transport sector significantly impact air quality, especially at the local scale.&nbsp; In many cities throughout the world, emissions from road, rail, and ship traffic can contribute large amounts of air pollution, including criteria and toxic po...

Optimal use of Hierarchical Bayesian Model (HBM)-assembled aerosol optical depth (AOD)-PM2.5&nbsp;fused surfaces in epidemiologic studies requires homogeneous temporal and spatial fused surfaces. No analytical method is available to evaluate spatial heterogeneity. The temporal ca...

In the early 2000s, concerns grew over the environmental persistence and bioaccumulation potential, and long half_lives in humans of longer chain per- and polyfluoroalkyl substances (PFAS), in particular, perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS). Dep...

The nuclear factor-kappa B (NF-&kappa;B) is a transcription factor with important roles in inflammation, immune response, and oncogenesis. Dysregulation of NF-&kappa;B signaling is associated with inflammation and certain cancers. We developed a gene expression biomarker predicti...

Exposure to fine particulate matter (PM2.5) is associated with asthma development as well as asthma exacerbation in children. PM2.5&nbsp;can be directly emitted or can form in the atmosphere from pollutant precursors. PM2.5&nbsp;emitted and formed in the atmosphere is influenced ...

As new approach methodologies (NAMs) continue to be developed and adopted, an ongoing barrier for in vitro cell and tissue culture assays is the process of validation. A major advantage of human cell and tissue culture models is the ability to improve the accuracy of translation ...

The emissions of chemicals from indoor, or &ldquo;near-field&rdquo;, sources such building materials and household articles contribute significantly to human exposure. These chemicals may include plasticizers (e.g., phthalates), flame retardants, synthetic fragrances, environment...

Despite decades of investigation, test methods to identify chemical respiratory allergens remain an unmet regulatory need. A critical advantage to the development of human cell and tissue culture models for sensitization is the ability to improve the accuracy of translation of re...

The Environmental Relative Moldiness Index (ERMI) is a scale used to compare mold contamination levels in United States (US) homes. To create the ERMI scale, a nationally representative set of U.S. homes was selected (n&thinsp;=&thinsp;1096). From each of these homes, a standard ...

Introduction and objective: Systematic review tools that provide guidance on evaluating epidemiology studies are receiving increasing attention and support because their application facilitates improved quality of the review,&nbsp;consistency across reviewers, and transparency fo...

Background/Aim: The evidence on exposure &ndash; health associations for chemicals with an extensive research history often includes studies with heterogeneous results. These studies may include various study designs examining different outcome and...

ABSTRACT - For Paper in Non-EPA Proceeding-Early life exposure to an adverse environment during critical or sensitive periods of respiratory and immune development may increase risk of developing chronic diseases of various organ systems, including respiratory conditions, through...