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Records 1 to 25 of 52 records from author Denise Macmillan

2024
Brennan, A., D. Chang, J. Cowden, S. Davidson-Fritz, J. Dean, M. Devito, J. Ford, L. Everett, A. Harrill, S. Hester, M. Hughes, J. Lambert, L. Lizarraga, R. Mezencev, D. Macmillan, G. Patlewicz, Kristina Chialton, R. Thomas, K. Vitense, L. Wehmas, A. Renyer, S. Auerbach, AND W. Casey. EPA Transcriptomic Assessment Product (ETAP) for Perfluoro-3-Methoxypropanoic Acid. U.S. Environmental Protection Agency, Washington, DC, EPA/600/X-24/066, 2024. https://doi.org/10.23645/epacomptox.25352962
Jackson, T., C. Lambright, N. Evans, L. Wehmas, D. Macmillan, J. Bangma, L. Gray, AND J. Conley. Exploring maternal and developmental toxicity of PFO4DA and PFO5DoA using hepatic transcriptomics and serum metabolomics. Society of Toxicology Annual Meeting, Salt Lake City, UT, March 10 - 14, 2024.
Brennan, A., D. Chang, J. Cowden, S. Davidson-Fritz, J. Dean, M. Devito, J. Ford, L. Everett, A. Harrill, S. Hester, M. Hughes, J. Lambert, L. Lizarraga, R. Mezencev, D. Macmillan, G. Patlewicz, K. Thayer, R. Thomas, K. Vitense, L. Wehmas, A. Renyer, S. Auerbach, W. Casey, R. Sams, S. Hunter, W. Cascio, K. Holt, S. Jones, R. Subramaniam, G. Rice, J. Bucher, T. Buckley, P. Egeghy, K. Paul-Friedman, J. Harrill, K. Isaacs, R. Judson, J. Kaiser, S. Masten, F. Parham, D. Petersen, A. Phillips, J. Sobus, Dan Villeneuve, P. White, A. Williams, G. Woodall, AND J. Zhao. Standard Methods for Development of EPA Transcriptomic Assessment Products (ETAPs). U.S. Environmental Protection Agency, Washington, DC, EPA/600/X-23/083, 2024. https://doi.org/10.23645/epacomptox.25365496
2023
Beasley, T., J. Dye, D. Freeborn, D. Herr, Andy Johnstone, Prasada Rao Kodavanti, U. Kodavanti, Chris Lau, Kathy McDaniel, D. Macmillan, J. McGee, C. Miller, W. Oshiro, Mette C Schladweiler, M. Valdez, AND S. Vulimiri. Assessing Environmental Health Disparities in Vulnerable Groups: Interactions Between Chemical Stressors and Social Factors That Impact Children’s Health and Development. U.S. EPA Office of Research and Development, Washington, DC, EPA/600/R-23/101, 2023.
Jarnagin, A., E. Korol-Bexell, A. Brennan, J. Ford, J. Wambaugh, D. Macmillan, M. Hughes, AND B. Wetmore. Cross Species Comparisons of Toxicokinetic Parameters for In Vitro-In Vivo Correlation Analyses. SOT, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.22294393
Renyer, A., B. Payne, W. Willis, A. Brennan, AND D. Macmillan. Development of a Python Script to Aid in Identification of Biotransformation Products of Emerging PFAS. Presented at SERMACS, Durham, NC, October 25 - 28, 2023. https://doi.org/10.23645/epacomptox.24790626
Renyer, A., K. Ravindra, B. Wetmore, J. Ford, M. Devito, M. Hughes, L. Wehmas, AND D. Macmillan. Dose Response, Dosimetric, and Metabolic Evaluations of Replacement PFAS Perfluoro-(2,5,8-trimethyl-3,6,9-trioxadodecanoic) Acid (HFPO-TeA). Toxics. MDPI, Basel, Switzerland, 11(12):951, (2023). https://doi.org/10.3390/toxics11120951
Renyer, A., B. Payne, M. Devito, M. Hughes, L. Wehmas, AND D. Macmillan. Dosimetry and Potential Bioaccumulation of a GenX Oligomer HFPO-TeA. Presented at SOT, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.22272334
Buckley, T., J. Sobus, J. McCord, J. Bangma, D. Macmillan, A. Williams, S. Urban, Y. Chai, S. Greene, K. Hanson, R. Rushing, E. Newman, W. Linck, E. Kalve, AND M. Small. Enabling State Adoption of Non-Targeted Analysis (NTA) to Address Pressing Public Health Needs: Maryland, Minnesota, and California Leading the Way (ISES 2023). ISES, Chicago, IL, August 27 - 31, 2023. https://doi.org/10.23645/epacomptox.23928921
Whitehead, H., J. Sobus, J. McCord, J. Bangma, D. Macmillan, A. Swank, T. Ferland, A. Chao, A. Williams, E. Carr, G. Janesch, S. Urban, Z. Cao, S. Muneem, Y. Chai, S. Greene, A. Dahlmeier, K. Hanson, R. Rushing, S. Saravia, E. Newman, W. Linck, E. Kalve, M. Small, AND T. Buckley. Enabling State Adoption of Non-Targeted Analysis (NTA) to Address Pressing Public Health Needs: Maryland, Minnesota, and California Leading the Way (SETAC 2023). SETAC, Louisville, KY, November 12 - 16, 2023. https://doi.org/10.23645/epacomptox.24794538
Brennan, A., S. Shaut, A. Renyer, R. Payne, J. Ford, M. Devito, M. Hughes, L. Wehmas, AND D. Macmillan. Identification of Biotransformation Products (BPs) in Rats Exposed to 6:1 Fluorotelomer Alcohol (6:1 FTOH). SETAC, Louisville, KY, November 12 - 16, 2023. https://doi.org/10.23645/epacomptox.24526438
Bounds, J., A. Renyer, AND D. Macmillan. Internal dose and in-life results after short-term exposure of rats to short-chain PFAS. Presented at SERMACS, Durham, NC, October 25 - 28, 2023. https://doi.org/10.23645/epacomptox.24585240
2022
Conley, J., C. Lambright, N. Evans, E. Medlock Kakaley, D. Jenkins-Hill, J. McCord, M. Strynar, L. Wehmas, S. Hester, D. Macmillan, AND L. Gray. Developmental toxicity of Nafion byproduct 2 (NBP2) in the Sprague-Dawley rat with comparisons to hexafluoropropylene oxide-dimer acid (HFPO-DA or GenX) and perfluorooctane sulfonate (PFOS). ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, Netherlands, 160:107056, (2022). https://doi.org/10.1016/j.envint.2021.107056
MacMillan, D., A. Renyer, M. Smeltz, M. Phillips, K. Ravindra, M. Devito, M. Hughes, L. Wehmas, AND B. Wetmore. Evaluations of in vivo and in vitro dosimetry and metabolic biotransformation of the hexafluoropropylene oxide homologue HFPO-TeA, an emerging per-and polyfluoroalkyl substance (PFAS). SETAC, Pittsburgh, PA, November 13 - 17, 2022. https://doi.org/10.23645/epacomptox.21552594
Beasley, T., K. McDaniel, W. Oshiro, V. Moser, D. MacMillan, AND D. Herr. Impacts of a perinatal exposure to manganese coupled with maternal stress in rats: Maternal somatic measures and the postnatal growth and development of rat offspring. NEUROTOXICOLOGY AND TERATOLOGY. Elsevier Science Ltd, New York, NY, 90:107061, (2022). https://doi.org/10.1016/j.ntt.2021.107061
Renyer, A., D. MacMillan, M. Devito, M. Hughes, AND L. Wehmas. Internal Dose and In-Life Results of Perfluoro-2,5,8-trimethyl-3,6,9-trioxadodecanoic acid Exposure from Short Term Dosing Studies in Rats. ASMS Conference on Mass Spectrometry and Allied Topics, Minneapolis, MN, June 05 - 09, 2022. https://doi.org/10.23645/epacomptox.19890808
Renyer, A., D. MacMillan, M. Devito, M. Hughes, AND L. Wehmas. Internal dose of perfluoro-3-methoxypropanoic acid in rat plasma and in-life effects from short term dosing studies. Society of Toxicology, San Diego, CA, March 27 - 31, 2022. https://doi.org/10.23645/epacomptox.19341683
MacMillan, D., A. Renyer, M. Devito, M. Hughes, AND L. Wehmas. Nontargeted analysis for identification of PFAS biotransformation products in rat plasma. American Society for Mass Spectrometry Conference, Minneapolis, MN, June 05 - 09, 2022. https://doi.org/10.23645/epacomptox.19908283
MacMillan, D., A. Renyer, M. Devito, M. Hughes, AND L. Wehmas. Nontargeted analysis for identification of PFAS biotransformation products in rat plasma. SETAC NTA, Durham, NC, May 22 - 26, 2022. https://doi.org/10.23645/epacomptox.19758634
Seim, R., D. Glinski, C. Lavelle, J. Awkerman, B. Hemmer, P. Harris, Sandy Raimondo, M. Snyder, Brad Acrey, Tom Purucker, D. MacMillan, A. Brennan, AND Matt Henderson. Using metabolomic profiling to inform use of surrogate species in ecological risk assessment practices. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY - PART D: GENOMICS AND PROTEOMICS. Elsevier BV, AMSTERDAM, Netherlands, 41:100947, (2022). https://doi.org/10.1016/j.cbd.2021.100947
2021
Richardson, V., J. Strasser, M. Mocanu, AND D. MacMillan. A Multi-Analyte Method for the Quantification of Xenobiotic-Induced Thyroxine Metabolism. International Society for the Study of Xenobiotics (ISSX), NA, NC, September 13 - 17, 2021. https://doi.org/10.23645/epacomptox.20292402
Imam, S., Z. He, S. Rogstad, S. Burks, J. Raymick, B. Robinson, E. Cuevas, S. Sarkar, C. Law, J. Hanig, D. Herr, D. MacMillan, A. Smith, S. Liachenko, O. James, C. Somps, C. Tyszkiewicz, C. Liu, G. Teuns, K. Ruprecht, M. Kothe, C. Otto, J. Pierson, R. Roberts, B. Gong, W. Tong, M. Aschner, M. Kallman, M. Paule, AND W. Slikker. Biomarkers of Chemical-induced Central Nervous System Damage. Safety Pharmacology Society, N/A, Virtual Meeting, October 04 - 08, 2021.
Imam, S., Z. He, S. Rogstad, S. Burks, J. Raymick, B. Robinson, E. Cuevas, S. Sarkar, C. Law, J. Hanig, D. Herr, D. MacMillan, A. Smith, S. Lachenko, J. O'Callaghan, C. Somps, I. Pardo, C. Aluise, K. Vlasakova, J. Levin, G. Teuns, K. Ruprecht, N. Evangelou, C. Kothe, T. Piia, C. Otto, F. Tekle, L. Mostovy, J. Pierson, R. Roberts, B. Gong, W. Tong, M. Aschner, M. Kallman, M. Paule, AND W. Slikker. Circulating Biomarkers of Central Nervous System Damage: Translating Preclinical Endpoints to Clinical Outcomes. Society for Neuroscience, Chicago, Illinois, November 13 - 17, 2021.