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Enabling State Adoption of Non-Targeted Analysis (NTA) to Address Pressing Public Health Needs: Maryland, Minnesota, and California Leading the Way (SETAC 2023)
Citation:
Whitehead, H., J. Sobus, J. McCord, J. Bangma, D. Macmillan, A. Swank, T. Ferland, A. Chao, A. Williams, E. Carr, G. Janesch, S. Urban, Z. Cao, S. Muneem, Y. Chai, S. Greene, A. Dahlmeier, K. Hanson, R. Rushing, S. Saravia, E. Newman, W. Linck, E. Kalve, M. Small, AND T. Buckley. Enabling State Adoption of Non-Targeted Analysis (NTA) to Address Pressing Public Health Needs: Maryland, Minnesota, and California Leading the Way (SETAC 2023). SETAC, Louisville, KY, November 12 - 16, 2023. https://doi.org/10.23645/epacomptox.24794538
Impact/Purpose:
This ROAR project focuses on the transfer of non-targeted analysis techniques to three partner regions and will report feasibility and lessons learned from widescale implementation of this cutting-edge technique. This presentation focuses on early lessons learned for NTA transfer for PFAS analysis.
Description:
Environmental health concerns over per- and polyfluoroalkyl substances (PFAS) are spurring states to adopt non-targeted analysis methods (NTA). The need for NTA is underscored by the approximate 100-fold difference between the number of chemicals making up the class relative to the few (<50) compounds that are routinely included in targeted analysis methods. The use of NTA can provide a more comprehensive assessment of PFAS environmental occurrence to inform public health protective strategies based on source attribution, exposure potential, hazard and risk assessment, and management strategies. However, there are significant barriers to state adoption of NTA including instrument cost, analytical expertise, and complex data processing workflows and tools. To overcome or mitigate these barriers, EPA’s Office of Research and Development (ORD) has been working to develop methods, tools, and data processing workflows along with technical collaborations to enable NTA adoption and technology transfer. To assess barriers more comprehensively and evaluate developed tools, EPA/ORD and regional offices (Regions 3, 5, and 9) partnered with three states (MD, MN, and CA) leading efforts to deploy NTA to address location-specific scenarios of environmental health concern. This presentation will provide an overview of lessons learned through this collaboration, state motivations to adopt NTA, study plans, barriers to implementation, and strategies for overcoming those barriers. Together, this collaboration will provide a roadmap and best practices for EPA engagement as other states and regions develop an interest in pursuing NTA. Disclaimer: The views expressed in this abstract are those of the authors and do not necessarily represent the views or policies of the US EPA.
URLs/Downloads:
DOI: Enabling State Adoption of Non-Targeted Analysis (NTA) to Address Pressing Public Health Needs: Maryland, Minnesota, and California Leading the Way (SETAC 2023)
POSTER.PDF (PDF, NA pp, 1876.449 KB, about PDF)