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See all EPA publications for Elaina Kenyon Include records from any EPA source

Records 1 to 25 of 97 records from [ORD-NHEERL] from author Elaina Kenyon

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2019

Kenyon, E. Physiologically Based Pharmacokinetic (PBPK) Modeling Contaminants of Concern in Drinking Water. American College of Toxicology, Phoenix, AZ, November 17 - 20, 2019. https://doi.org/10.23645/epacomptox.22572697

Kenyon, E., J. Lipscomb, R. Pegram, BJ George, AND R. Hines. THE IMPACT OF SCALING FACTOR VARIABILITY ON RISK-RELEVANT PHARMACOKINETIC OUTCOMES IN CHILDREN: A CASE STUDY USING BROMODICHLOROMETHANE (BDCM). TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 167(2):347-359, (2019). https://doi.org/10.1093/toxsci/kfy236

2018

Kenyon, E., C. Eklund, J. Simmons, AND R. Pegram. FACTORS INFLUENCING PREDICTION OF BROMODICHLOROMETHANE (BDCM) IN EXHALED BREATH: FURTHER EVALUATION OF A HUMAN BDCM PBPK MODEL. Society of Toxicology, San Antonio, Texas, March 11 - 15, 2018.

Kenyon, E., R. Pegram, J. Lipscomb, AND R. Hines. Impact of Scaling Factor Variation on Pharmacokinetic Outcomes in Pediatric Populations: a Case Study Using Bromodichloromethane (BDCM). FutureTox IV, Crystal City, VA, November 14 - 16, 2018.

Kenyon, E. AND M. Hughes. Oral Exposure and Absorption of Toxicants. Chapter 1, Comprehensive Toxicology, 3rd ed. Elsevier: Oxford, OXFORD, Uk, 1:98-111, (2018).

2017

Rooney, J., N. Ryan, B. Chorley, S. Hester, E. Kenyon, Judy Schmid, BJ George, M. Hughes, Y. Sey, A. Tennant, D. MacMillan, J. Simmons, C. McQueen, A. Pandiri, C. Wood, AND C. Corton. Genomic effects of androstenedione and sex-specific liver cancer susceptibility in mice. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 160(1):15–29, (2017).

Pegram, R., E. Kenyon, Steve Simmons, D. DeMarini, B. Chorley, A. Teal, AND T. Ross. Molecular Mechanisms by Which Chlorinated Water Causes Bladder Cancer. 48th Annual Meeting of the Environmental Mutagenesis and Genomics Society, Raleigh, North Carolina, September 09 - 13, 2017.

Kenyon, E., C. Eklund, R. Pegram, AND J. Simmons. PBPK-MODEL ESTIMATES OF BROMODICHLOROMETHANE (BDCM) DELIVERY TO THE HUMAN URINARY BLADDER. Gordon Research Conference, Mt Holyoke, Massachusetts, July 30 - August 04, 2017.

Kenyon, E., R. Pegram, AND R. Hines. Scaling Factor Variability and Toxicokinetic Outcomes in Children. Childrens Environmental Health Network Research Conference, Washington, DC, April 05 - 07, 2017.

Kenyon, E., J. Lipscomb, R. Pegram, AND R. Hines. THE IMPACT OF SCALING FACTOR VARIABILITY ON RISK-RELEVANT TOXICOKINETIC OUTCOMES IN CHILDREN: A CASE STUDY USING BROMODICHLOROMETHANE (BDCM). Society of Toxicology, Baltimore, Maryland, March 12 - 16, 2017.

2016

Kenyon, E., T. Leavens, C. Eklund, AND R. Pegram. Development and Application of a Human PBPK Model for Bromodichloromethane (BDCM) to Investigate Impacts of Multi-Route Exposure. JOURNAL OF APPLIED TOXICOLOGY. John Wiley & Sons, Ltd., Indianapolis, IN, 36(9):1095-1111, (2015).

Lake, A., C. Wood, V. Bhat, B. Chorley, G. Carswell, Y. Sey, E. Kenyon, B. Padnos, T. Moore, A. Tennant, Judy Schmid, BJ George, D. Ross, M. Hughes, C. Corton, J. Simmons, C. McQueen, AND S. Hester. Dose and Effect Thresholds for Early Key Events in a Mode of PPARa-Mediated Action. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 149(2):312-325, (2016).

Kenyon, E., C. Eklund, J. Simmons, AND R. Pegram. PBPK-MODEL ESTIMATES OF BROMODICHLOROMETHANE (BDCM) DISTRIBUTION IN URINE AND BLADDER TISSUE. Society of Toxicology, New Orleans, LA, March 12 - 17, 2016.

Kenyon, E., C. Eklund, J. Lipscomb, AND R. Pegram. The impact of variation in scaling factors on the estimation of internal dose metrics: a case study using bromodichloromethane (BDCM). Toxicology Mechanisms and Methods. Taylor & Francis, Inc., Philadelphia, PA, 26(8):620-626, (2016).

2015

Garcia, R., J. Ibrahim, J. Wambaugh, E. Kenyon, AND Woodrow Setzer. Identifiability of PBPK Models with Applications to Dimethylarsinic Acid Exposure. JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS. Springer, New York, NY, , 1-19, (2015).

Kenyon, E. AND H. Clewell III. Toxicokinetics and Pharmacokinetic Modeling of Arsenic. Edition 1, Chapter 22, J. Christopher States (ed.), Arsenic: Exposure Sources, Health Risks, and Mechanism of Toxicity, edited by J. Christopher States, Chpt. 27, John Wiley & Sons, Inc., Hoboken, NJ. John Wiley & Sons Incorporated, New York, NY, 1:884-908, (2015).

2012

KENYON, E. M., R. A. PEGRAM, C. R. EKLUND, AND J. C. LIPSCOMB. COMPARISON OF IN VIVO DERIVED AND SCALED IN VITRO METABOLIC RATE CONSTANTS FOR SOME VOLATILE ORGANIC COMPOUNDS (VOCS). Presented at Society of Toxicology (SOT) Annual Meeting, San Francisco, CA, March 11 - 15, 2012.

KENYON, E. M. Interspecies Extrapolation. Chapter 19, Brad Reisfeld and Arthur Mayeno (ed.), Computational Toxicology. Humana Press Incorporated, Totowa, NJ, 1:501-520, (2012).

KENYON, E. M. Physiologically based pharmacokinetic (PBPK) modeling considering methylated trivalent arsenicals. Presented at Society of Toxicology Annual Meeting, San Francisco, CA, March 11 - 15, 2012.

2011

KENYON, E. M., T. L. Leavens, C. Eklund, AND R. A. PEGRAM. APPLICATION OF A MULTIROUTE HUMAN PBPK MODEL FOR BROMODICHLOROMETHANE (BDCM). Presented at Society of Toxicology (SOT) Annual Meeting, Washington, DC, March 06 - 10, 2011.

Clewell, H. J., R. S. Thomas, E. M. KENYON, M. F. HUGHES, B. ADAIR, P. R. Gentry, AND J. W. Yager. Concentration-and time-dependent genomic changes in the mouse urinary bladder following exposure to arsenate in drinking water for up to twelve weeks. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 123(2):421-32, (2011).

OSHIRO, W. M., E. M. KENYON, C. J. GORDON, B. Bishop, Q. T. KRANTZ, J. Ford, AND P. J. BUSHNELL. Extrapolating the Acute Behavioral Effects of Toluene from 1-Hour to 24-Hour Exposures in Rats: Roles of Dose Metric, and Metabolic and Behavioral Tolerance. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 123(1):180-92, (2011).

BUSHNELL, P. J., W. M. OSHIRO, Q. T. KRANTZ, C. J. GORDON, E. M. KENYON, AND J. Ford. PREDICTING THE ACUTE BEHAVIORAL EFFECTS OF TOLUENE INHALED FOR 24 HRS IN RATS: DOSE METRICS, METABOLISM AND BEHAVIORAL TOLERANCE. Presented at International Neurotoxicology Association Meeting, X'ian, CHINA, June 05 - 10, 2011.

2010

GORDON, C. J., R. R. GOTTIPOLU, E. M. KENYON, R. THOMAS, M. SCHLADWEILER, C. M. MACK, J. H. SHANNAHAN, G. WALLENBORN, A. NYSKA, R. C. MACPHAIL, J. E. RICHARDS, M. J. DEVITO, AND U. P. KODAVANTI. AGING AND SUSCEPTIBILITY TO TOLUENE IN RATS: A PHARMACOKINETIC, BIOMARKER, AND PHYSIOLOGICAL APPROACH. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH - PART A: CURRENT ISSUES. Taylor & Francis, Inc., Philadelphia, PA, 73(4):301-318, (2010).

Boellmann, F., L. Zhang, H. J. Clewell, E. M. KENYON, M. E. Andersen, AND R. S. Thomas. Genome wide analysis of DNA methylation and gene expression changes in the mouse lung following subchronic arsenate exposure. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 117(2):404-417, (2010).