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25
of 30 records from [ORD-NHEERL] published between 12/13/2013 and 12/13/2018 from author John Nichols
2018
Fitzsimmons, P., A. Hoffman, K. Fay, AND J. Nichols. Allometric scaling of hepatic biotransformation in rainbow trout. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY - PART C: TOXICOLOGY & PHARMACOLOGY . Elsevier Science Ltd, New York, NY, 214:52-60, (2018). https://doi.org/10.1016/j.cbpc.2018.08.004
Nichols, J., M. Ladd, AND P. Fitzsimmons. Measurement of kinetic parameters for biotransformation of polycyclic aromatic hydrocarbons by trout liver S9 fractions: Implications for bioaccumulation assessment. Applied In Vitro Toxicology. Mary Ann Liebert, Inc., Larchmont, NY, 4(4):365-378, (2018). https://doi.org/10.1089/aivt.2017.0005
Saunders, L., A. Hoffman, P. Fitzsimmons, J. Nichols, AND F. Gobas. Quantitative in vitro - in vivo extrapolation of biotransformation rates for bioaccumulation assessment: Focus on organic sunscreen agents in trout. SETAC North America, Sacramento, CA, November 04 - 08, 2018.
Nichols, J., K. Fay, M. Bernhard, I. Bischof, J. Davis, M. Halder, J. Hu, K. Johanning, H. Laue, D. Nabb, C. Schlechtriem, H. Segner, J. Swintek, J. Weeks, AND M. Embry. Reliability of In Vitro methods used to measure intrinsic clearance of hydrophobic organic chemicals by rainbow trout: Results of an international ring trial. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 164(2):563-575, (2018). https://doi.org/10.1093/toxsci/kfy113
Frew, J., J. Brown, P. Fitzsimmons, A. Hoffman, M. Sadilek, C. Grue, AND J. Nichols. Toxicokinetics of the neonicotinoid insecticide imidacloprid in rainbow trout (Oncorhynchus mykiss). COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY - PART C: TOXICOLOGY & PHARMACOLOGY . Elsevier Science Ltd, New York, NY, 205:34-42, (2018).
Arnot, J., M. Embry, J. Armitage, AND J. Nichols. Updated models for predicting biotransformation impacts on chemical bioconcentration in rainbow trout. SETAC North America, Sacramento, CA, November 04 - 08, 2018.
2017
Fitzsimmons, P., A. Hoffman, K. Fay, AND J. Nichols. Allometric scaling of hepatic biotransformation in rainbow trout. SETAC North America, Minneapolis, MN, November 12 - 16, 2017.
Armitage, J., R. Erickson, T. Luckenbach, C. Ng, R. Prosser, J. Arnot, K. Schirmer, AND J. Nichols. Assessing the bioaccumulation potential of ionizable organic compounds: Current knowledge and research priorities. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 36(4):882-879, (2017).
Fay, K., P. Fitzsimmons, A. Hoffman, AND J. Nichols. Comparison of trout hepatocytes and liver S9 fractions as in vitro models for predicting hepatic clearance in fish. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 36(2):463-471, (2017).
Haselman, J., J. Nichols, M. Hornung, Pat Kosian, J. Olker, Joe Korte, AND S. Degitz. Computational modeling of the amphibian thyroid axis supported by targeted in vivo testing to advance quantitative adverse outcome pathway development. National Society of Toxicology Annual Meeting, Baltimore, MD, March 12 - 16, 2017.
Nichols, J. Development of physiologically based toxicokinetic (PBTK) models for fish: Confessions of a former fish physiologist. SETAC North America, Minneapolis, MN, November 12 - 16, 2017.
2016
Fay, K., P. Fitzsimmons, A. Hoffman, AND J. Nichols. Comparison of trout hepatocytes and liver S9 fractions as in vitro models for predicting hepatic clearance in fish. setac north america, Orlando, FL, November 06 - 10, 2016.
Saunders, L., A. Hoffman, J. Nichols, AND F. Gobas. Concentration dependence of in vivo biotransformation rates of organic sunscreen agents in rainbow trout following a dietary exposure. SETAC North America, Orlando, FL, November 06 - 10, 2016.
Embry, M., K. Fay, M. Bernard, I. Bischof, J. Davis, J. Domoradzki, M. Halder, J. Hu, K. Johanning, H. Laue, J. Nichols, H. Peterson, C. Schlechtriem, H. Segner, AND J. Weeks. In vitro to in vivo extrapolation of hepatic metabolism in fish: An inter-laboratory comparison of in vitro methods - presentation. SETAC North America, Orlando, FL, November 06 - 10, 2016.
Ladd, M., P. Fitzsimmons, AND J. Nichols. Optimization of a UDP-glucuronosyltransferase assay for trout liver S9 fractions: Activity enhancement by alamethicin, a pore-forming peptide. XENOBIOTICA. Taylor & Francis, Inc., Philadelphia, PA, 46(12):1066-1075, (2016).
Nichols, J., L. Saunders, AND F. Gobas. Physiologically based modeling of hepatic and gastrointestinal biotransformation in fish. SETAC North America, Orlando, FL, November 06 - 10, 2016.
Consoer, D., A. Hoffman, P. Fitzsimmons, Pat Kosian, AND J. Nichols. Toxicokinetics of perfluorooctane sulfonate in rainbow trout (Oncorhynchus mykiss). ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 35(3):717-727, (2016).
Chen, Y., J. Hermens, M. Jonkers, J. Arnot, J. Armitage, T. Brown, J. Nichols, K. Fay, AND S. Droge. Which molecular features affect the intrinsic hepatic clearance rate of ionizable organic chemicals in fish? ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 50:12722-12730, (2016).
2015
Nichols, J. Frontiers of chemical bioaccumulation modeling with fish. UMD Seminar, Duluth, MN, March 27, 2015.
Fay, K., M. Embry, M. Bernard, I. Bischof, J. Davis, J. Domoradzki, M. Halder, X. Han, K. Johanning, H. Laue, D. Nabb, J. Nichols, C. Schlechtriem, H. Segner, L. van der Wal, AND J. Weeks. In vitro to In vivo extrapolation of hepatic metabolism in fish: An inter-laboratory comparison of In vitro methods. SETAC North America, Salt Lake City, UT, November 01 - 05, 2015.
Nichols, J., B. Du, R. Erickson, A. Hoffman, J. Berninger, C. Chambliss, K. Connors, AND B. Brooks. Observed and modeled effects of pH on bioconcentration of diphenhydramine, a weakly basic pharmaceutical, by fathead minnows. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 34(6):1425-1435, (2015).
Nichols, J., F. Gobas, M. McLeod, K. Borgi, P. Leonards, P. Ester, H. Laue, AND J. Arnot. Summary of Cefic-LRI sponsored workshop: Recent scientific developments in bioaccumulation research. In Proceedings, Cefic-LRI-Field Research, Helsinki, FINLAND, September 24, 2014. Cefic, Brussels, Belgium, 1-13, (2015).
2014
Nichols, J., M. Hornung, Joe Korte, J. Haselman, Joe Tietge, AND S. Degitz. A quantitative adverse outcome pathway model for thyroid axis disruption in Xenopus laevis tadpoles. SETAC North America, Vancouver, BC, CANADA, November 09 - 13, 2014.
Armitage, J., G. Rattray, AND J. Nichols. Experts Workshop on the Ecotoxicological Risk Assessment of Ionizable Organic Chemicals: Bioaccumulation/ADME. SETAC North America, Vancouver, BC, CANADA, November 09 - 13, 2014.
Gouin, T., B. Brooks, M. Bonnell, J. Armitage, B. Escher, T. Henry, M. Lam, J. Nichols, G. Rattray, G. Stringer, T. Valenti, AND M. Embry. Experts workshop on the ecotoxicological risk assessment of ionizable organic chemicals: Towards a science-based framework for chemical assessment. SETAC North America, Vancouver, BC, CANADA, November 09 - 13, 2014.