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25
of 39 records published between 12/13/2013 and 12/13/2018 from author John Nichols
2018
Fitzsimmons, P., A. Hoffman, K. Fay, AND J. Nichols. Allometric scaling of hepatic biotransformation in rainbow trout. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY - PART C: TOXICOLOGY & PHARMACOLOGY . Elsevier Science Ltd, New York, NY, 214:52-60, (2018). https://doi.org/10.1016/j.cbpc.2018.08.004
Foster, K., A. Looky, J. Armitage, M. Embry, J. Nichols, B. Wetmore, AND J. Arnot. Critical Evaluation of a Human In Vitro Biotransformation Rate Database: Case Study of Seven Chemicals (SETAC Europe - 2018). SETAC Europe 2018 Annual Meeting, Rome, ITALY, May 13 - 17, 2018.
Nichols, J., M. Ladd, AND P. Fitzsimmons. Measurement of kinetic parameters for biotransformation of polycyclic aromatic hydrocarbons by trout liver S9 fractions: Implications for bioaccumulation assessment. Applied In Vitro Toxicology. Mary Ann Liebert, Inc., Larchmont, NY, 4(4):365-378, (2018). https://doi.org/10.1089/aivt.2017.0005
Saunders, L., A. Hoffman, P. Fitzsimmons, J. Nichols, AND F. Gobas. Quantitative in vitro - in vivo extrapolation of biotransformation rates for bioaccumulation assessment: Focus on organic sunscreen agents in trout. SETAC North America, Sacramento, CA, November 04 - 08, 2018.
Nichols, J., K. Fay, M. Bernhard, I. Bischof, J. Davis, M. Halder, J. Hu, K. Johanning, H. Laue, D. Nabb, C. Schlechtriem, H. Segner, J. Swintek, J. Weeks, AND M. Embry. Reliability of In Vitro methods used to measure intrinsic clearance of hydrophobic organic chemicals by rainbow trout: Results of an international ring trial. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 164(2):563-575, (2018). https://doi.org/10.1093/toxsci/kfy113
Frew, J., J. Brown, P. Fitzsimmons, A. Hoffman, M. Sadilek, C. Grue, AND J. Nichols. Toxicokinetics of the neonicotinoid insecticide imidacloprid in rainbow trout (Oncorhynchus mykiss). COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY - PART C: TOXICOLOGY & PHARMACOLOGY . Elsevier Science Ltd, New York, NY, 205:34-42, (2018).
Arnot, J., M. Embry, J. Armitage, AND J. Nichols. Updated models for predicting biotransformation impacts on chemical bioconcentration in rainbow trout. SETAC North America, Sacramento, CA, November 04 - 08, 2018.
2017
Fitzsimmons, P., A. Hoffman, K. Fay, AND J. Nichols. Allometric scaling of hepatic biotransformation in rainbow trout. SETAC North America, Minneapolis, MN, November 12 - 16, 2017.
Armitage, J., R. Erickson, T. Luckenbach, C. Ng, R. Prosser, J. Arnot, K. Schirmer, AND J. Nichols. Assessing the bioaccumulation potential of ionizable organic compounds: Current knowledge and research priorities. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 36(4):882-879, (2017).
Fay, K., P. Fitzsimmons, A. Hoffman, AND J. Nichols. Comparison of trout hepatocytes and liver S9 fractions as in vitro models for predicting hepatic clearance in fish. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 36(2):463-471, (2017).
Haselman, J., J. Nichols, M. Hornung, Pat Kosian, J. Olker, Joe Korte, AND S. Degitz. Computational modeling of the amphibian thyroid axis supported by targeted in vivo testing to advance quantitative adverse outcome pathway development. National Society of Toxicology Annual Meeting, Baltimore, MD, March 12 - 16, 2017.
Foster, K., A. Looky, J. Armitage, M. Embry, J. Nichols, B. Wetmore, AND J. Arnot. Critical Evaluation of a Human In Vitro Biotransformation Rate Database. 2017 SETAC North America Annual Meeting, MN, Minneapolis, November 12 - 16, 2017.
Ingle, B., B. Veber, J. Nichols, J. Wambaugh, AND R. Tornero-Velez. Designing a Quantitative Structure-Activity Relationship for the Intrinsic Metabolic Clearance of Environmentally Relevant Chemicals. Presented at Society of Toxicology 56th Annual Meeting and ToxExpo, Baltimore, MD, March 12 - 16, 2017.
Nichols, J. Development of physiologically based toxicokinetic (PBTK) models for fish: Confessions of a former fish physiologist. SETAC North America, Minneapolis, MN, November 12 - 16, 2017.
Ingle, B., B. Veber, J. Nichols, J. Wambaugh, AND R. Tornero-Velez. In Silico Prediction of Toxicokinetic Parameters for Environmentally Relevant Chemicals for Risk-Based Prioritization. OpenTox USA 2017, Durham, NC, July 12 - 13, 2017.
Ingle, B., B. Veber, J. Nichols, J. Wambaugh, AND R. Tornero-Velez. In Silico Prediction of Toxicokinetic Parameters for Environmentally Relevant Chemicals with Application to Risk-Based Prioritization. 2017 ISES Annual Meeting, Research Triangle Park, NC, October 15 - 19, 2017.
2016
Fay, K., P. Fitzsimmons, A. Hoffman, AND J. Nichols. Comparison of trout hepatocytes and liver S9 fractions as in vitro models for predicting hepatic clearance in fish. setac north america, Orlando, FL, November 06 - 10, 2016.
Saunders, L., A. Hoffman, J. Nichols, AND F. Gobas. Concentration dependence of in vivo biotransformation rates of organic sunscreen agents in rainbow trout following a dietary exposure. SETAC North America, Orlando, FL, November 06 - 10, 2016.
Ingle, B., B. Veber, J. Nichols, AND R. Tornero-Velez. Human health and the environment: Predicting plasma protein binding and metabolic clearance rates of environmentally relevant chemicals. American Chemical Society Nat'l Meeting, San Diego, CA, San Diego, CA, March 13 - 17, 2016.
Embry, M., K. Fay, M. Bernard, I. Bischof, J. Davis, J. Domoradzki, M. Halder, J. Hu, K. Johanning, H. Laue, J. Nichols, H. Peterson, C. Schlechtriem, H. Segner, AND J. Weeks. In vitro to in vivo extrapolation of hepatic metabolism in fish: An inter-laboratory comparison of in vitro methods - presentation. SETAC North America, Orlando, FL, November 06 - 10, 2016.
Ingle, B., R. Tornero-Velez, J. Nichols, AND B. Veber. Informing the Human Plasma Protein Binding of Environmental Chemicals by Machine Learning in the Pharmaceutical Space: Applicability Domain and Limits of Predictability. Journal of Chemical Information and Modeling. American Chemical Society, Washington, DC, 56(11):2243-2252, (2016).
Ladd, M., P. Fitzsimmons, AND J. Nichols. Optimization of a UDP-glucuronosyltransferase assay for trout liver S9 fractions: Activity enhancement by alamethicin, a pore-forming peptide. XENOBIOTICA. Taylor & Francis, Inc., Philadelphia, PA, 46(12):1066-1075, (2016).
Nichols, J., L. Saunders, AND F. Gobas. Physiologically based modeling of hepatic and gastrointestinal biotransformation in fish. SETAC North America, Orlando, FL, November 06 - 10, 2016.
Ingle, B., B. Veber, J. Nichols, AND R. Tornero-Velez. Toxicity challenges in environmental chemicals: Prediction of human plasma protein binding through quantitative structure-activity relationship (QSAR) models. IVIE Workshop RTP, NC, RTP, NC, February 17, 2016.
Ingle, B., B. Veber, J. Nichols, AND R. Tornero-Velez. Toxicity challenges in environmental chemicals: Prediction of human plasma protein binding through quantitative structure-activity relationship (QSAR) models (2016 IVIVE Workshop Proceedings). In Proceedings, IVIVE Workshop, RTP, NC, February 17, 2016. U.S. Department of Health & Human Services, NIEHS, Research Triangle Park, NC, 4, (2016).