Office of Research and Development Publications

National Health And Environmental Effects Research Laboratory (NHEERL) Research Publications

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Records 1 to 16 of 16 records from [ORD-NHEERL] published between 01/21/2013 and 01/21/2018 from author Alex Hoffman

2017

Fitzsimmons, P., A. Hoffman, K. Fay, AND J. Nichols. Allometric scaling of hepatic biotransformation in rainbow trout. SETAC North America, Minneapolis, MN, November 12 - 16, 2017.

Fay, K., P. Fitzsimmons, A. Hoffman, AND J. Nichols. Comparison of trout hepatocytes and liver S9 fractions as in vitro models for predicting hepatic clearance in fish. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 36(2):463-471, (2017).

2016

Consoer, D., A. Hoffman, P. Fitzsimmons, Pat Kosian, AND J. Nichols. Toxicokinetics of perfluorooctane sulfonate in rainbow trout (Oncorhynchus mykiss). ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 35(3):717-727, (2016).

2015

Nichols, J., B. Du, R. Erickson, A. Hoffman, J. Berninger, C. Chambliss, K. Connors, AND B. Brooks. Observed and modeled effects of pH on bioconcentration of diphenhydramine, a weakly basic pharmaceutical, by fathead minnows. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 34(6):1425-1435, (2015).

2014

Fay, K., R. Mingoia, I. Goeritz, D. Nabb, A. Hoffman, B. Ferrell, H. Peterson, J. Nichols, H. Segner, AND X. Han. Intra- and inter-laboratory reliability of a cryopreserved trout hepatocyte assay for the prediction of chemical bioaccumulation potential. ENVIRONMENTAL SCIENCE AND TECHNOLOGY. John Wiley & Sons, Ltd., Indianapolis, IN, 48(14):8170-8178, (2014).

Nichols, J., B. Du, J. Berninger, K. Connors, K. Chambliss, R. Erickson, A. Hoffman, AND B. Brooks. Observed and modeled effects of pH on bioconcentration of diphenhydramine, a weakly basic pharmaceutical, in fathead minnows. SETAC, Vancouver, BC, CANADA, November 09 - 13, 2014.

Fay, K., P. Fitzsimmons, A. Hoffman, AND J. Nichols. Optimizing the use of rainbow trout hepatocytes for bioaccumulation assessments with fish. XENOBIOTICA. Taylor & Francis, Inc., Philadelphia, PA, 44(4):345-351, (2014).

Consoer, D., A. Hoffman, P. Fitzsimmons, Pat Kosian, AND J. Nichols. Toxicokinetics of perfluorooctanoate (PFOA) in rainbow trout(Oncorhynchus mykiss). AQUATIC TOXICOLOGY. Elsevier Science Ltd, New York, NY, 156:65-73, (2014).

2013

Connors, K., B. Du, P. Fitzsimmons, A. Hoffman, C. Chambliss, J. Nichols, AND B. Brooks. Comparative pharmaceutical metabolism by rainbow trout (Oncorhynchus mykiss) liver S9 fractions. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 32(8):1810-1818, (2013).

Nichols, J., A. Hoffman, T. Ter Laak, AND P. Fitzsimmons. Hepatic clearance of 6 polyaromatic aromatic hydrocarbons by isolated trout livers: Prediction from in vitro clearance by liver S9 fractions. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 136(2):359-372, (2013).

Fitzsimmons, P., A. Hoffman, AND J. Nichols. Incremental improvements to the trout S9 biotransformation assay. Presented at SETAC, Nashville, TN, November 17 - 21, 2013.

Fay, K., R. Mingoia, I. Goeritz, D. Nabb, A. Hoffman, B. Ferrell, H. Peterson, J. Nichols, H. Segner, AND X. Han. Inter-laboratory comparison of clearance rates of xenobiotics by cryopreserved trout hepatocytes for the prediction of bioaccumulation potential. Presented at Society of Toxicology, March 10 - 14, 2013.

Fay, K., R. Mingoia, I. Goeritz, D. Nabb, A. Hoffman, B. Ferrell, H. Peterson, J. Nichols, H. Segner, AND X. Han. Inter-laboratory comparison of xenobiotic clearance rates determined using cryopreserved trout hepatocytes for improving bioaccumulation predictions. Presented at Health and Environmental Sciences Institute, Duluth, MN, November 01, 2013.