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Records 1 to 25 of 55 records from [ORD-NERL] published between 07/20/2012 and 07/20/2017 from author Cecilia Tan

2017
Escher, B., J. Hackermüller, T. Polte, S. Scholz, A. Aigner, R. Altenburger, A. Bohme, S. Bopp, W. Brack, W. Busch, M. Chadeau-Hyam, A. Covaci, A. Eisentrager, J. Galligan, N. Garcia-Reyero, T. Hartung, M. Hein, G. Herberth, A. Jahnke, J. Kleinjans, N. Kluever, M. Krauss, M. Lamoree, I. Lehmann, T. Luckenbach, G. Miller, A. Mueller, D. Phillips, T. Reemtsma, U. Rolle-Kampczyk, G. Schuurmann, B. Schwikowski, C. Tan, S. Trump, S. Walter-Rohde, AND J. Wambaugh. From the exposome to mechanistic understanding of chemical-induced adverse effects. ENVIRONMENT INTERNATIONAL. Elsevier Science Ltd, New York, NY, 99:97-106, (2017).
Leonard, J., C. Stevens, K. Mansouri, D. Chang, AND C. Tan. Identifying Metabolically Active Chemicals Using a Consensus Quantitative Structure Activity Model for Estrogen Receptor Binding. SOT Annual Meeting, Baltimore, MD, March 12 - 16, 2017.
Leonard, J., C. Stevens, K. Mansouri, D. Chang, AND C. Tan. Identifying Metabolically Active Chemicals Using a Consensus Quantitative Structure Activity Relationship Model for Estrogen Receptor Binding. Opentox USA 2017, Durham, NC, July 12 - 13, 2017.
Tan, C. Improving Public Health through Innovations in Exposure Science. Socieity of Toxicology Annual Meeting, Baltimore, MD, March 12 - 16, 2017.
Tan, C. Integrating Aggregate Exposure Pathway (AEP) and Adverse Outcome Pathway (AOP) Frameworks to Estimate Exposure-relevant Responses. JRC Workshop: Fit-For-Purpose Exposure Assessment For Risk-Based Decision Making, Como, ITALY, June 20, 2017.
Mansouri, K., J. Leonard, C. Tan, M. Yoon, P. McMullen, AND R. Clewell. Scoring and ranking of metabolic trees to computationally prioritize chemicals for testing using fit-for-purpose in vitro estrogen receptor assay. OpenTox USA 2017, Durham, NC, July 12 - 13, 2017.
Moreau, M., J. Leonard, K. Phillips, J. Campbell, S. Pendse, C. Nicolas, M. Phillips, M. Yoon, C. Tan, S. Smith, H. Pudukodu, K. Isaacs, AND H. Clewell. Using exposure prediction tools to link exposure and dosimetry for risk based decisions: a case study with phthalates. 2017 SOT Annual Meeting, Baltimore, MD, March 12 - 16, 2017.
2016
Phillips, M., J. Leonard, Chris Grulke, D. Chang, S. Edwards, R. Brooks, M. Goldsmith, H. El-Masri, AND C. Tan. A Workflow to Investigate Exposure and Pharmacokinetic Influences on High-Throughput in Vitro Chemical Screening Based on Adverse Outcome Pathways. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 124(1):53-60, (2016).
Lu, J., M. Goldsmith, Chris Grulke, D. Chang, J. Leonard, E. Hypes, AND C. Tan. A comprehensive physiologically based pharmacokinetic knowledgebase and web-based interface for rapid model ranking and querying. Society of Toxicology 55th Annual Meeting and ToxExpo, New Orleans, LA, March 13 - 17, 2016.
Teeguarden, J., C. Tan, S. Edwards, P. Egeghy, J. Leonard, K. Anderson, R. Corley, A. Harding, M. Kile, S. Simonich, D. Stone, R. Tanguay, K. Waters, S. Harper, D. Williams, J. Orme-Zavaleta, AND T. Bahadori. A conceptual framework to support exposure science research and complete the source-to-outcome continuum for risk assessment. ISES 2016 Annual Meeting, Utrecht, NETHERLANDS, October 09 - 13, 2016.
Teeguarden, J., C. Tan, S. Edwards, J. Leonard, K. Anderson, R. Corley, M. Kile, S. Simonich, D. Stone, R. Tanguay, K. Waters, S. Harper, AND D. Williams. Completing the Link between Exposure Science and Toxicology for Improved Environmental Health Decision Making: The Aggregate Exposure Pathway Framework. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 50(9):4579-4586, (2016).
Csiszar, S., D. Meyer, K. L. Dionisio, P. Egeghy, K. K. Isaacs, P. Price, K. Scanlon, Yu-Mei Tan, K. Thomas, D. Vallero, AND J. Bare. Conceptual Framework To Extend Life Cycle Assessment Using Near-Field Human Exposure Modeling and High-Throughput Tools for Chemicals. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 50(21):11922-11934, (2016).
Lu, J., M. Goldsmith, C. Grulke, D. Chang, R. Brooks, J. Leonard, M. Phillips, E. Hypes, M. Fair, R. Tornero-Velez, J. Johnson, C. Dary, AND C. Tan. Developing a Physiologically-Based Pharmacokinetic Model Knowledgebase in Support of Provisional Model Construction. PLOS Computational Biology. Public Library of Science, San Francisco, CA, 12(2):e1004495, (2016).
Leonard, J., A. Sobel Leonard, D. Chang, S. Edwards, J. Lu, S. Scholle, P. Key, M. Winter, K. Isaacs, AND C. Tan. Evaluating the Impact of Uncertainties in Clearance and Exposure When Prioritizing Chemicals Screened in High-Throughput Assays. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 50(11):5961–5971, (2016).
Tan, C., J. Leonard, S. Scholle, M. Winter, P. Key, J. Lu, AND D. Chang. Evaluating the Value of Augmenting In Vitro Hazard Assessment with Exposure and Pharmacokinetics Considerations for Chemical Prioritization. Society of Toxicology Conf, New Orleans, LA, March 13 - 17, 2016.
Tan, C. Evolving PBPK applications in regulatory risk assessment: current situation and future goals. Physiologically-based kinetic modeling in risk assessment – reaching a whole new level in regulatory, Ispra, ITALY, November 17 - 18, 2016.
Teeguarden, J., C. Tan, S. Edwards, J. Leonard, K. Anderson, R. Corley, M. Kile, S. Massey Simonich, D. Stone, R. Tanguay, K. Waters, S. Harper, AND D. Williams. Expanding on Successful Concepts, Models, and Organization. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 50(17):8921–8922, (2016).
Tan, C., H. El-Masri, S. Edwards, J. Leonard, S. Suarez, AND K. Fay. Integration of chemical-specific exposure and pharmacokinetic information with the chemical-agnostic AOP framework to support high throughput risk assessment. Chemical Safety for Sustainability Subcommittee Meeting, Durham, NC, November 16 - 17, 2016.
Tan, C. Pieces of the Puzzle: Tracking the Chemical Component of the Exposome (Helmholtz Centre for Environmental Research UFZ). Helmholtz Centre for Environmental Research UFZ, Leipzig, GERMANY, December 14 - 15, 2016.
Tan, C., S. Edwards, J. Teeguarden, P. Egeghy, AND J. Leonard. The Aggregate Exposure Pathway (AEP): A conceptual framework for advancing exposure science research and transforming risk assessment. SETAC North America 37th Annual Meeting, Orlando, FL, November 06 - 10, 2016.
2015
Tan, C., J. Leonard, D. Chang, H. El-Masri, S. Edwards, AND R. Goldsmith. A three-tiered approach for linking pharmacokinetic considerations to the adverse outcome pathway framework for chemical-specific risk assessment. SETAC, Salt Lake City, UT, Salt Lake City, UT, November 01 - 04, 2015.