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Records 1 to 25 of 141 records from [ORD-NCCT] from author Rhyne Setzer

2019
Wambaugh, J., B. Wetmore, C. Ring, C. Nicolas, R. Pearce, G. Honda, R. Dinallo, D. Angus, J. Gilbert, T. Sierra, A. Badrinarayanan, B. Snodgrass, A. Brockman, C. Strock, R. Setzer, AND R. Thomas. Assessing Toxicokinetic Uncertainty and Variability in Risk Prioritization. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 172(2):235-251, (2019). https://doi.org/10.1093/toxsci/kfz205
Ring, C., J. Arnot, D. Bennett, P. Egeghy, P. Fantke, L. Huang, K. Isaacs, O. Jolliet, K. Phillips, P. Price, H. Shin, J. Westgate, R. Setzer, AND J. Wambaugh. Consensus Modeling of Median Chemical Intake for the U.S. Population Based on Predictions of Exposure Pathways. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 53(2):719-732, (2019). https://doi.org/10.1021/acs.est.8b04056
Harrill, J., I. Shah, R. Setzer, D. Haggard, S. Auerbach, R. Judson, AND R. Thomas. Considerations for Strategic Use of High-Throughput Transcriptomics Chemical Screening Data in Regulatory Decisions. Current Opinion in Toxicology. Elsevier BV, AMSTERDAM, Netherlands, 15:64-75, (2019). https://doi.org/10.1016/j.cotox.2019.05.004
Haggard, D., Woodrow Setzer, R. Judson, AND K. Friedman. Development of a prioritization method for chemical-mediated effects on steroidogenesis using an integrated statistical analysis of high-throughput H295R data. REGULATORY TOXICOLOGY AND PHARMACOLOGY. Elsevier Science Ltd, New York, NY, 109:104510, (2019). https://doi.org/10.1016/j.yrtph.2019.104510
Judson, R., I. Shah, Woodrow Setzer, D. Haggard, T. Sheffield, AND J. Harrill. Modeling Pathway Interactions using High-Throughput Transcriptomics Data. Presented at Society of Toxicology (SOT) annual meeting, Baltimore, MD, March 10 - 14, 2019.
Paini, A., J. Leonard, E. Joossens, J. Bessems, A. Desalegn, J. Dorne, J. Gosling, M. Heringa, M. Klaric, T. Kliment, N. Kramer, G. Loizou, J. Louisse, A. Lumen, J. Madden, E. Patterson, S. Proença, A. Punt, Woodrow Setzer, N. Suciu, J. Troutman, M. Yoon, A. Worth, AND C. Tan. Next generation physiologically based kinetic (NG-PBK) models in support of regulatory decision making. Computational Toxicology. Elsevier B.V., Amsterdam, Netherlands, 9:61-72, (2019). https://doi.org/10.1016/j.comtox.2018.11.002
Haggard, D., Woodrow Setzer, R. Judson, AND K. Paul-Friedman. Prioritization of chemicals for effects on steroidogenesis using an integrated statistical approach to high-throughput H295R data (SOT). Presented at Society of Toxicology annual meeting, Baltimore, MD, March 10 - 14, 2019. https://doi.org/10.23645/epacomptox.7873802
Wambaugh, J., R. Pearce, C. Strope, Woodrow Setzer, AND N. Sipes. R Package httk. U.S. Environmental Protection Agency, Washington, DC, 2019.
Honda, G., R. Pearce, L. Pham, R. Setzer, B. Wetmore, N. Sipes, J. Gilbert, B. Franz, R. Thomas, AND J. Wambaugh. Using the Concordance of In Vitro and In Vivo Data to Evaluate Extrapolation Assumptions. PLOS ONE . Public Library of Science, San Francisco, CA, 14(5):1-33, (2019). https://doi.org/10.1371/journal.pone.0217564
2018
Sayre, R., Woodrow Setzer, J. Wambaugh, AND Chris Grulke. A Method to Quantify Reproducibility in PBPK Model Methods and Results . Presented at OpenTox, RTP, NC, July 11 - 12, 2018. https://doi.org/10.23645/epacomptox.7080740
Honda, G., R. Pearce, L. Pham, B. Wetmore, N. Sipes, Woodrow Setzer, R. Thomas, AND J. Wambaugh. Applying a High-Throughput PBTK Model for IVIVE. Presented at Society of Toxicology Annual Meeting, San Antonio, TX, March 11 - 15, 2018.
Harrill, J., I. Shah, Woodrow Setzer, C. Willis, D. Haggard, R. Judson, AND R. Thomas. Concentration-Response Screening of Environmental Chemicals for In Vitro Point-of-Departure Determination using a Targeted RNA-Seq Whole Transcriptome Assay. Society for Laboratory Automation and Screening Conference, San Diego,CA, February 03 - 07, 2018. https://doi.org/10.23645/epacomptox.6950033
Wambaugh, J., Woodrow Setzer, K. Isaacs, R. Sayre, AND K. Phillips. Consensus Exposure Predictions with the SEEM Framework. Presented at American Industrial Hygiene Association Webinar, RTP, NC, June 04, 2018. https://doi.org/10.23645/epacomptox.6953195
Brown, J., E. Watt, Woodrow Setzer, R. Judson, AND K. Paul-Friedman. Defining uncertainty in publicly available high-throughput screening data from the ToxCast program. Presented at 57th Annual Meeting of the Society of Toxicology, San Antonio, Texas, March 11 - 15, 2018. https://doi.org/10.23645/epacomptox.7028990
Harrill, J., I. Shah, Woodrow Setzer, D. Haggard, M. Martin, R. Judson, S. Malcomber, A. White, AND R. Thomas. Differential Gene Expression and Concentration-Response Modeling Workflow for High-Throughput Transcriptomic (HTTr) Data: Results From MCF7 Cells. Society of Toxicology, San Antonio, TX, March 11 - 15, 2018.
Setzer, Woodrow AND C. Tan. EURL ECVAM WORKSHOP ON NEW GENERATION OF PHYSIOLOGICALLY-BASED KINETIC MODELS IN RISK ASSESSMENT. Publications Office of the European Union, , Luxembourg, 2018. https://doi.org/10.2760/619902
Wambaugh, J., M. Hughes, C. Ring, D. MacMillan, J. Ford, T. Fennell, S. Black, R. Snyder, N. Sipes, B. Wetmore, J. Westerhout, Woodrow Setzer, R. Pearce, J. Simmons, AND R. Thomas. Evaluating In Vitro-In Vivo Extrapolation of Toxicokinetics. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 163(1):152-169, (2018). https://doi.org/10.1093/toxsci/kfy020
Wambaugh, J., B. Wetmore, R. Pearce, G. Honda, R. Sayre, K. Paul-Friedman, Woodrow Setzer, AND R. Thomas. Evaluating New Approach Methodologies for Toxicokinetics. International Society of Exposure Science annual meeting, OttawaCON, August 26 - 30, 2018. https://doi.org/10.23645/epacomptox.7072652
Haggard, D., A. Karmaus, M. Martin, R. Judson, Woodrow Setzer, AND K. Paul-Friedman. Evaluating perturbation of in vitro steroidogenesis using a high-throughput H295R assay. Presented at Society of Toxicology Annual Meeting, San Antonio, Texas, March 11 - 15, 2018. https://doi.org/10.23645/epacomptox.6827660
Haggard, D., A. Karmaus, M. Martin, R. Judson, Woodrow Setzer, AND K. Paul-Friedman. High-throughput H295R steroidogenesis assay: utility as an alternative and a statistical approach to characterize effects on steroidogenesis. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 162(2):509-534, (2018). https://doi.org/10.1093/toxsci/kfx274
Shah, I., J. Harrill, Woodrow Setzer, D. Haggard, R. Judson, A. Karmaus, M. Martin, AND R. Thomas. Predicting Chemical Mechanisms of Action using High-Throughput Transcriptomic Data. Society of Toxicology, San Antonio, TX, March 11 - 15, 2018.
Wambaugh, J., K. Isaacs, K. Phillips, P. Egeghy, AND Woodrow Setzer. Predicting Exposure Pathways Allows Risk-Based Prioritization. Presented at The Toxicology Forum 42nd Annual Winter Meeting, Washington, District Of Columbia, January 29 - 31, 2018. https://doi.org/10.23645/epacomptox.6876962
Truong, L., G. Ouedraogo, L. Pham, J. Clouzeau, S. Loisel-Joubert, D. Blanchet, H. Noçairi, Woodrow Setzer, R. Judson, Chris Grulke, K. Mansouri, AND M. Martin. Predicting In Vivo Effect Levels for Repeat Dose Systemic Toxicity using Chemical, Biological, Kinetic and Study Covariates. Archives of Toxicology. Springer, New York, NY, 92(2):587-600, (2018).
Haggard, Derik E., Woodrow Setzer, R. Judson, AND K. Paul-Friedman. Prioritization of Chemicals for Effects on Steroidogenesis Using an Integrated Statistical Approach to High-Throughput H295R Data. Presented at FutureToxIV - Predictive Toxicology for Healthy Children, Arlington, VA, November 14 - 16, 2018. https://doi.org/10.23645/epacomptox.7488530
Pearce, R., R. Sayre, Woodrow Setzer, Chris Grulke, R. Thomas, AND J. Wambaugh. Replication of PBTK Models for Bisphenol A with High-Throughput TK Models. Presented at Society of Toxicology Annual Meeting, San Antonio, Texas, March 11 - 15, 2018. https://doi.org/10.23645/epacomptox.7017293