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Records 1 to 25 of 152 records from [ORD-NCCT] from author Russell Thomas

2020
Krewski, D., M. Andersen, M. Tyshenko, K. Krishnan, T. Hartung, K. Boekelheide, J. Wambaugh, D. Jones, M. Whelan, R. Thomas, C. Yauk, T. Barton-Maclaren, AND I. Cote. (Archives of Toxicology) Toxicity Testing in the 21st Century: Progress in the Past Decade and Future Perspectives. Archives of Toxicology. Springer, New York, NY, 94(1):1-58, (2020). https://doi.org/10.1007/s00204-019-02613-4
Deisenroth, C., V. Soldatow, J. Ford, W. Stewart, C. Brinkman, E. LeCluyse, D. Macmillan, AND R. Thomas. Development of an In Vitro Human Thyroid Microtissue Model for Chemical Screening (ToxSci). TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 174(1):63-78, (2020). https://doi.org/10.1093/toxsci/kfz238
Zurlinden, T., K. Saili, N. Rush, P. Kothiya, R. Judson, K. Houck, E. Hunter, N. Baker, J. Palmer, R. Thomas, AND T. Knudsen. Profiling the ToxCast Library With a Pluripotent Human (H9) Stem Cell Line-Based Biomarker Assay for Developmental Toxicity. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 174(2):189-209, (2020). https://doi.org/10.1093/toxsci/kfaa014
Friedman, K., M. Gagne, L. Loo, P. Karamertzanis, T. Netzeva, T. Sobanski, J. Franzosa, A. Richard, R. Lougee, A. Gissi, J. Lee, M. Angrish, J. Dorne, S. Foster, K. Raffaele, T. Bahadori, M. Gwinn, J. Lambert, M. Whelan, M. Rasenberg, T. Barton-Maclaren, AND R. Thomas. Utility of In Vitro Bioactivity as a Lower Bound Estimate of In Vivo Adverse Effect Levels and in Risk-Based Prioritization. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 173(1):202-225, (2020). https://doi.org/10.1093/toxsci/kfz201
2019
Thomas, R. 20190710 - Looking Back to Go Forward in Toxicology and Chemical Risk Assessment (ICCR). International Cooperation on Cosmetics Regulations (ICCR), Montreal, N/A, CANADA, July 10 - 12, 2019. https://doi.org/10.23645/epacomptox.9816956
Thomas, R. A Chemical Category-Based Approach for Selecting and Screening PFAS for Toxicity and Toxicokinetic Testing. Presented at Society of Environmental Toxicology and Chemistry (SETAC) Focus Topic Meeting, Durham, NC, August 12 - 15, 2019. https://doi.org/10.23645/epacomptox.9742535
Patlewicz, G., A. Richard, A. Williams, C. Grulke, R. Sams, J. Lambert, Pamela Noyes, M. DeVito, R. Hines, M. Strynar, A. GuiseppiElie, AND R. Thomas. A Chemical Category-Based Prioritization Approach for Selecting 75 Per- and Polyfluoroalkyl Substances (PFAS) for Tiered Toxicity and Toxicokinetic Testing. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 127(1):1-12, (2019). https://doi.org/10.1289/EHP4555
Gwinn, M., T. Barton-Maclaren, M. Rasenberg, AND R. Thomas. Accelerating the Pace of Chemical Risk Assessment (APCRA): Continuing the Discussion of Regulatory Application of New Approach Methodologies. Presented at Society of Toxicology annual meeting, Baltimore, MD, March 10 - 14, 2019.
Degroot, D., T. Zurlinden, R. Thomas, M. Lee, P. Carmichael, AND C. Deisenroth. Alginate Immobilization of Metabolic Enzymes (AIME) Coupled to an Estrogen Receptor Transactivation Assay Detects Bioactivated and Bioinactivated Estrogen Receptor Agonists. Presented at Society of Toxicology annual meeting, Baltimore, MD, March 10 - 14, 2019. https://doi.org/10.23645/epacomptox.7868357
Wetmore, B., R. Clewell, B. Cholewa, B. Parks, S. Pendse, M. Black, K. Mansouri, S. Haider, E. Berg, R. Judson, K. Houck, M. Martin, H. Clewell III, M. Andersen, R. Thomas, AND P. McMullen. Assessing Bioactivity-Exposure Profiles of Fruits and Vegetables in the BioMAP Profiling System. TOXICOLOGY IN VITRO. Elsevier Science Ltd, New York, NY, 54:41-57, (2019). https://doi.org/10.1016/j.tiv.2018.09.006
Wambaugh, J., B. Wetmore, C. Ring, C. Nicolas, R. Pearce, G. Honda, R. Dinallo, D. Angus, J. Gilbert, T. Sierra, A. Badrinarayanan, B. Snodgrass, A. Brockman, C. Strock, R. Setzer, AND R. Thomas. Assessing Toxicokinetic Uncertainty and Variability in Risk Prioritization. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 172(2):235-251, (2019). https://doi.org/10.1093/toxsci/kfz205
Philips, J., D. Svoboda, A. Tandon, S. Patel, A. Sedykh, D. Mav, B. Kuo, C. Yauk, L. Yang, R. Thomas, Jeff Gift, Allen Davis, L. Olysyzk, F. Parham, T. Saddler, R. Shah, S. Auerbach, B. Merrick, AND R. Paules. BMDExpress 2: Enhanced transcriptomic dose-response analysis workflow. BIOINFORMATICS. Oxford University Press, Cary, NC, 35(10):1780-1782, (2019). https://doi.org/10.1093/bioinformatics/bty878
Thomas, R. Characterization and Integration of Uncertainty Across Alternative Methods for Hazard, Toxicokinetics, and Exposure. Presented at Society of Toxicology annual meeting, Baltimore, MD, March 10 - 14, 2019.
Thomas, R. Coming to Terms with the State of the Science in Toxicology and Defining a Path for the Future. Presented at Netherlands Society of Toxicology Conference, Ede, N/A, NETHERLANDS, June 10 - 13, 2019. https://doi.org/10.23645/epacomptox.8984174
Harrill, J., I. Shah, R. Setzer, D. Haggard, S. Auerbach, R. Judson, AND R. Thomas. Considerations for Strategic Use of High-Throughput Transcriptomics Chemical Screening Data in Regulatory Decisions. Current Opinion in Toxicology. Elsevier BV, AMSTERDAM, Netherlands, 15:64-75, (2019). https://doi.org/10.1016/j.cotox.2019.05.004
Deisenroth, C., V. Soldatow, J. Ford, W. Stewart, C. Brinkman, D. Macmillan, E. LeCluyse, AND R. Thomas. Development of an In Vitro Human Thyroid Microtissue Model for Chemical Screening. Presented at Society of Toxicology annual meeting, Baltimore, MD, March 10 - 14, 2019. https://doi.org/10.23645/epacomptox.7848353
Gannon, A., M. Moreau, R. Farmahin, R. Thomas, T. Barton-Maclaren, A. Nong, I. Curran, AND C. Yauk. Hexabromocyclododecane (HBCD): A case study applying tiered testing for human health risk assessment. FOOD AND CHEMICAL TOXICOLOGY. Elsevier Science Ltd, New York, NY, 131:110581, (2019). https://doi.org/10.1016/j.fct.2019.110581
Honda, G., R. Sayre, C. Strock, D. Angus, R. Dinallo, R. Pearce, R. Thomas, AND J. Wambaugh. QSAR Modeling of Caco-2 Permeability for the Estimation of Oral Bioavailability. Presented at Society of Toxicology Annual Meeting, Baltimore, MD, March 10 - 14, 2019. https://doi.org/10.23645/epacomptox.7841102
DeGroot, D., R. Thomas, Steve Simmons, AND C. Deisenroth. Retrofit Strategies for the Incorporation of Metabolic Competence into In Vitro Assays. Presented at Society of Toxicology Annual Meeting, Baltimore, MD, March 10 - 14, 2019.
Paul-Friedman, K., M. Gagné, T. Barton-Maclaren, J. Bucher, R. Thomas, M. Rasenberg, AND T. Sobanksi. Retrospective and Prospective Case Studies to Accelerate the Pace of Chemical Risk Assessment. Presented at Society of Toxicology annual meeting, Baltimore, MD, March 10 - 14, 2019. https://doi.org/10.23645/epacomptox.7873742
Thomas, R. Understanding Potential Human Health Impacts from High Content Data. Presented at Society of Toxicology Annual Meeting, Baltimore, MD, March 10 - 14, 2019.
Honda, G., R. Pearce, L. Pham, R. Setzer, B. Wetmore, N. Sipes, J. Gilbert, B. Franz, R. Thomas, AND J. Wambaugh. Using the Concordance of In Vitro and In Vivo Data to Evaluate Extrapolation Assumptions. PLOS ONE . Public Library of Science, San Francisco, CA, 14(5):1-33, (2019). https://doi.org/10.1371/journal.pone.0217564
Judson, R., R. Thomas, N. Baker, A. Simha, X. Howey, C. Marable, N. Kleinstreuer, AND K. Houck. Workflow for Defining Reference Chemicals for Assessing Performance of In Vitro Assays. ALTEX. Society ALTEX Edition, Kuesnacht, Switzerland, 36(2):261-276, (2019). https://doi.org/10.14573/altex.1809281
Simha, A., R. Judson, R. Thomas, N. Baker, X. Howey, C. Marable, N. Kleinstreuer, AND K. Houck. Workflow for Defining Reference Chemicals to Assess Performance of In Vitro Assays. Presented at Society of Toxicology Annual Meeting, Baltimore, MD, March 10 - 14, 2019. https://doi.org/10.23645/epacomptox.7874000
2018
Grulke, Chris, A. Williams, R. Judson, AND R. Thomas. A Flexible Web-Interface for Integrating Multiple Data Streams in Support of Risk Prioritization of Environmental Chemicals. Presented at ACS, New Orleans, LA, March 18 - 22, 2018. https://doi.org/10.23645/epacomptox.6986996