Science Inventory

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Judson, R., D. Smith, M. Devito, J. Wambaugh, B. Wetmore, K. Friedman, G. Patlewicz, R. Thomas, R. Sayre, J. Olker, S. Degitz, S. Padilla, J. Harrill, T. Shafer, AND K. Carstens. A Comparison of In Vitro Points of Departure with Human Blood Levels for Per- and Polyfluoroalkyl Substances (PFAS). Society of Toxicology (SOT) 63rd Annual Meeting and ToxExpo, Salt Lake City, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25451677

Judson, R., D. Smith, M. Devito, J. Wambaugh, B. Wetmore, K. Friedman, G. Patlewicz, R. Thomas, R. Sayre, J. Olker, S. Degitz, S. Padilla, J. Harrill, T. Shafer, AND K. Carstens. A Comparison of In Vitro Points of Departure with Human Blood Levels for Per- and Polyfluoroalkyl Substances (PFAS) (Toxics). Toxics. MDPI, Basel, Switzerland, 12(4):271, (2024). https://doi.org/10.3390/toxics12040271

Browne, P., K. Friedman, K. Boekelheide, AND R. Thomas. Adverse effects in traditional and alternative toxicity tests. REGULATORY TOXICOLOGY AND PHARMACOLOGY. Elsevier Science Ltd, New York, NY, 148:105579, (2024). https://doi.org/10.1016/j.yrtph.2024.105579

Brennan, A., D. Chang, J. Cowden, S. Davidson-Fritz, J. Dean, M. Devito, J. Ford, L. Everett, A. Harrill, S. Hester, M. Hughes, J. Lambert, L. Lizarraga, R. Mezencev, D. Macmillan, G. Patlewicz, Kristina Chialton, R. Thomas, K. Vitense, L. Wehmas, A. Renyer, S. Auerbach, AND W. Casey. EPA Transcriptomic Assessment Product (ETAP) for Perfluoro-3-Methoxypropanoic Acid. U.S. Environmental Protection Agency, Washington, DC, EPA/600/X-24/066, 2024. https://doi.org/10.23645/epacomptox.25352962

Rogers, J., F. Leusch, B. Chambers, K. Daniels, L. Everett, R. Judson, K. Maruya, A. Mehinto, P. Neale, K. Friedman, R. Thomas, S. Snyder, AND J. Harrill. High-Throughput Transcriptomics of Water Extracts Detects Reductions in Biological Activity with Water Treatment Processes. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 58(4):2027-2037, (2024). https://doi.org/10.1021/acs.est.3c07525

Thomas, R. AND J. Lambert. New Additions to Address Important Gaps. SOT, Salt Lake City, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25408357

Thomas, R. Progress on Related EPA PFAS Research Activities. Presentation to the EPA Office of Chemical Safety and Pollution Prevention (OCSPP) Stakeholder PFAS Workshop February 2024, RTP, NC, February 14, 2024. https://doi.org/10.23645/epacomptox.25225862

Chang, D., J. Cowden, S. Davidson-Fritz, J. Dean, M. Devito, L. Everett, A. Harrill, S. Hester, M. Hughes, J. Lambert, L. Lizarraga, R. Mezencev, G. Patlewicz, R. Thomas, L. Wehmas, K. Vitense, S. Auerbach, W. Casey, R. Sams, S. Hunter, J. Bucher, T. Buckley, P. Egeghy, K. Paul-Friedman, J. Harrill, K. Isaacs, R. Judson, J. Kaiser, S. Masten, F. Parham, D. Petersen, A. Phillips, J. Sobus, Dan Villeneuve, P. White, A. Williams, G. Woodall, AND J. Zhao. Scientific Studies Supporting Development of Transcriptomic Points of Departure for EPA Transcriptomic Assessment Products (ETAPs). U.S. Environmental Protection Agency, Washington, DC, EPA/600/X-23/084, 2024. https://doi.org/10.23645/epacomptox.25365550

Brennan, A., D. Chang, J. Cowden, S. Davidson-Fritz, J. Dean, M. Devito, J. Ford, L. Everett, A. Harrill, S. Hester, M. Hughes, J. Lambert, L. Lizarraga, R. Mezencev, D. Macmillan, G. Patlewicz, K. Thayer, R. Thomas, K. Vitense, L. Wehmas, A. Renyer, S. Auerbach, W. Casey, R. Sams, S. Hunter, W. Cascio, K. Holt, S. Jones, R. Subramaniam, G. Rice, J. Bucher, T. Buckley, P. Egeghy, K. Paul-Friedman, J. Harrill, K. Isaacs, R. Judson, J. Kaiser, S. Masten, F. Parham, D. Petersen, A. Phillips, J. Sobus, Dan Villeneuve, P. White, A. Williams, G. Woodall, AND J. Zhao. Standard Methods for Development of EPA Transcriptomic Assessment Products (ETAPs). U.S. Environmental Protection Agency, Washington, DC, EPA/600/X-23/083, 2024. https://doi.org/10.23645/epacomptox.25365496

Hagiwara, S., G. Paoli, P. Price, M. Gwinn, A. Guiseppi-Elie, P. Farrell, B. Hubbell, D. Krewski, AND R. Thomas. A value of information framework for assessing the trade-offs associated with uncertainty, duration, and cost of chemical toxicity testing. RISK ANALYSIS. Blackwell Publishing, Malden, MA, 43(3):498-515, (2023). https://doi.org/10.1111/risa.13931

Wambaugh, J., T. Barton-Maclaren, M. Beal, M. Devito, J. Dorne, S. Ferguson, M. Hughes, R. Judson, A. Long, I. Moffat, K. Paul-Friedman, S. Stavroula, R. Thomas, AND B. Wetmore. APCRA Case Study: High Throughput Toxicokinetics for In Vitro-In Vivo Extrapolation. APCRA 7, Helsinki, FINLAND, April 25 - 27, 2023. https://doi.org/10.23645/epacomptox.22647385

Wambaugh, J., B. Savage, G. Honda, D. Crizer, M. Devito, S. Ferguson, M. Feshuk, J. Harrill, N. Sipes, R. Thomas, AND K. Paul-Friedman. Challenges of In Vitro Disposition Modeling: First Insights from the Tox21 Project. Society of Toxicology Annual Meeting, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.22263784

Buckley, T., P. Egeghy, K. Isaacs, A. Richard, C. Ring, R. Sayre, J. Sobus, R. Thomas, E. Ulrich, J. Wambaugh, AND A. Williams. Cutting-edge computational chemical exposure research at the U.S. Environmental Protection Agency. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, Netherlands, 178:108097, (2023). https://doi.org/10.1016/j.envint.2023.108097

Thomas, R. Development of a New Transcriptomics-Based Assessment Product for Data Poor Chemicals (American Forest & Paper). American Forest & Paper Association Meeting, RTP, NC, December 07, 2023.

Thomas, R. Development of a New Transcriptomics-Based Assessment Product for Data Poor Chemicals (OECD ESCA). Organization for Economic Co-operation and Development (OECD) Emerging Science for Chemical Assessment Meeting, Paris, FRANCE, June 29 - 30, 2023. https://doi.org/10.23645/epacomptox.23600679

Thomas, R. Development of a New Transcriptomics-Based Assessment Product for Data Poor Chemicals (OECD WPHA). Organization for Economic Co-operation and Development (OECD) Working Party for Hazard Assessment Update Meeting, Paris, FRANCE, June 27 - 28, 2023. https://doi.org/10.23645/epacomptox.23596332

Thomas, R. Development of a New Transcriptomics-Based Assessment Product for Data Poor Chemicals (PARC). PARC Meeting, RTP, NC, September 11, 2023. https://doi.org/10.23645/epacomptox.24128661

Thomas, R. Development of a New Transcriptomics-Based Assessment Product for Data Poor Chemicals (ToxForum Summer 23). The Toxicology Forum 2023 Summer Meeting, Pentagon City, VA, July 24 - 26, 2023. https://doi.org/10.23645/epacomptox.23751099

Thomas, R. EPA Research: Lessons from Toxicology NAMs. Complement Animal Research In Experimentation (Complement-ARIE) Inter-Agency Retreat, Bethesda, MD, October 19 - 20, 2023. https://doi.org/10.23645/epacomptox.24421228

Thomas, R. ETAP BOSC Day 1 Agenda and Charge Questions. EPA Transcriptomic Assessment Products (ETAP) Board of Scientific Counselors (BOSC) Panel, RTP, NC, July 11 - 12, 2023. https://doi.org/10.23645/epacomptox.23664207

Thomas, R. ETAP BOSC Day 2 Agenda and Charge Questions. EPA Transcriptomic Assessment Products (ETAP) Board of Scientific Counselors (BOSC) Panel, RTP, NC, July 11 - 12, 2023. https://doi.org/10.23645/epacomptox.23664213

Garnovskaya, M., M. Feshuk, W. Stewart, K. Friedman, R. Thomas, AND C. Deisenroth. Evaluation of a High-throughput H295R Homogenous Time Resolved Fluorescence Assay for Androgen and Estrogen Steroidogenesis Screening. TOXICOLOGY IN VITRO. Elsevier Science Ltd, New York, NY, 92:105659, (2023). https://doi.org/10.1016/j.tiv.2023.105659

Boyce, M., K. Favela, J. Bonzo, A. Chao, L. Lizarraga, L. Moody, E. Owens, G. Patlewicz, I. Shah, J. Sobus, R. Thomas, A. Williams, A. Yau, AND J. Wambaugh. Identifying xenobiotic metabolites with in silico prediction tools and LCMS suspect screening analysis. Frontiers in Toxicology. Frontiers, Lausanne, Switzerland, 5:1051483, (2023). https://doi.org/10.3389/ftox.2023.1051483

Thomas, R. Moving Past Measuring Adversity in an Intact Organism. European Chemicals Agency (ECHA) New approach methodologies workshop, Helsinki/Virtual, N/A, FINLAND, May 31 - June 01, 2023. https://doi.org/10.23645/epacomptox.23309843

Thomas, R. NAMs 101: The Basics and the EPA NAM Work Plan. American Chemistry Council Webinar, RTP, NC, October 18, 2023. https://doi.org/10.23645/epacomptox.24421714