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National Center For Computational Toxicology (NCCT) Research Publications

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Records 26 to 50 of 225 Presentation - Posters from [ORD-NCCT] published between 07/19/2013 and 07/19/2018

2018
Wynder, J., J. Ovesen, A. Maier, R. Judson, N. Kleinstreuer, AND M. Krishan. Evaluating the applicability of read-across tools and high throughput screening data for food relevant chemicals. Society of Toxicology, San Antonio,TX, March 11 - 15, 2018.
Paul-Friedman, K. AND R. Thomas. Examining the Utility of In Vitro Bioactivity as a Conservative Point of Departure: A Case Study. Presented at Office of Chemical Safety and Pollution Prevention (OCSPP) Visit to RTP June 2018, RTP, NC, June 08, 2018. https://doi.org/10.23645/epacomptox.6991130
Knudsen, T. AND S. Hunter. Framework for Predictive Developmental Toxicity of Chemicals Regulated under TSCA. Presented at Office of Chemical Safety and Pollution Prevention (OCSPP) Visit to RTP June 2018, RTP, NC, June 08, 2018. https://doi.org/10.23645/epacomptox.6991199
Paul-Friedman, K., S. Padilla, AND Tim Shafer. High-throughput screening in the ToxCast Program and TSCA Data Needs. Presented at Office of Chemical Safety and Pollution Prevention (OCSPP) Visit to RTP June 2018, RTP, NC, June 08, 2018. https://doi.org/10.23645/epacomptox.6991118
Wambaugh, J., J. Jackson, K. Brouwer, A. Herman, G. Honda, R. Pearce, AND R. Thomas. In Vitro Hepatobiliary Disposition Assessment of 15 Non-Therapeutic Chemicals in Sandwich-Culture Rat Hepatocytes using B-CLEAR® Technology. Presented at Society of Toxicology Annual Meeting, San Antonio, Texas, March 11 - 15, 2018. https://doi.org/10.23645/epacomptox.6987284
Nicolas, C., K. Phillips, M. Minto, X. Liu, K. Isaacs, C. Addington, A. Sumner, AND J. Wambaugh. Measuring the emissivity of semi-volatile organic compounds from articles of commerce. Society of Toxicology Annual Meeting, San Antonio,TX, March 11 - 15, 2018. https://doi.org/10.23645/epacomptox.6793724
Watford, S., L. Pham, J. Wignall, R. Shin, M. Martin, AND K. Paul-Friedman. New features in ToxRefDB to improve modeling applications and data integration. Presented at Society of Toxicology, San Antonio, Texas, March 11 - 15, 2018. https://doi.org/10.23645/epacomptox.6834827
Nyffeler, J., C. Willis, AND J. Harrill. Optimization and Application of a Multivariate Image-Based Phenotypic Profiling Assay for Screening of Environmental Chemicals in U-2 OS and MCF7 Cells. Presented at Society of Toxicology annual meeting, San Antonio, Texas, March 11 - 15, 2018. https://doi.org/10.23645/epacomptox.6850772
Nyffeler, J., C. Willis, AND J. Harrill. Optimization and Application of an Image-based Phenotypic Profiling Assay to Estimate in vitro Points of Departure for Chemical Bioactivity. Presented at SETAC North America Focused Topic Meeting : High-Throughput Screening, Durham, NC, April 16 - 18, 2018. https://doi.org/10.23645/epacomptox.7033271
Shah, I., J. Harrill, Woodrow Setzer, D. Haggard, R. Judson, A. Karmaus, M. Martin, AND R. Thomas. Predicting Chemical Mechanisms of Action using High-Throughput Transcriptomic Data. Society of Toxicology, San Antonio, TX, March 11 - 15, 2018.
Knudsen, T., T. Zurlinden, AND S. Hunter. Profiling the ToxCast library with pluripotent embryonic stem cell assays. Presented at Teratology Society Annual Meeting, Clearwater, FL, June 23 - 27, 2018. https://doi.org/10.23645/epacomptox.6949823
Williams, A., Chris Grulke, J. Dunne, N. Baker, R. Judson, AND J. Edwards. Public access to chemistry and toxicity data for 760,000 substances via the EPA CompTox Chemistry Dashboard. Presented at Homeland Security Poster Session, RTP, NC, May 09, 2018. https://doi.org/10.23645/epacomptox.6945626
Pearce, R., R. Sayre, Woodrow Setzer, Chris Grulke, R. Thomas, AND J. Wambaugh. Replication of PBTK Models for Bisphenol A with High-Throughput TK Models. Presented at Society of Toxicology Annual Meeting, San Antonio, Texas, March 11 - 15, 2018. https://doi.org/10.23645/epacomptox.7017293
Pham, L., S. Watford, Woodrow Setzer, AND K. Paul-Friedman. Reproducibility and variance of liver effects in subchronic and chronic repeat dose toxicity studies. Society of Toxicology Annual Meeting, San Antonio,TX, March 11 - 15, 2018.
DeGroot, D., R. Thomas, M. Lee, P. Carmichael, Steve Simmons, AND C. Deisenroth. Retrofitting an Estrogen Receptor Transactivation Assay with Metabolic Competence Using Alginate Immobilization of Metabolic Enzymes. Presented at SOT Annual Meeting, San Antonio, Texas, March 11 - 15, 2018.
DeGroot, D., R. Thomas, M. Lee, P. Carmichael, Steve Simmons, AND C. Deisenroth. Retrofitting an Estrogen Receptor Transactivation Assay with Metabolic Competence Using Alginate Immobilization of Metabolic Enzymes (AIME). SETAC High Throughput Screening and Environmental Risk Assessment, Durham,NC, April 16 - 18, 2018.
Houck, K., A. Bone, K. Paul-Friedman, C. Hsu, S. Sakamuru, M. Xia, R. Huang, V. Soni, D. Stavreva, AND K. Crofton. Screening the 10K Tox21 chemical library for thyroid hormone receptor modulators. Society of Toxicology, San Antonio, TX, March 11 - 15, 2018.
Pradeep, P. AND R. Judson. Structure-based QSAR Models to Predict Systemic Toxicity Points of Departure. Presented at SOT Annual Meeting, San Antonio, Texas, March 11 - 15, 2018.
Williams, A., Chris Grulke, AND J. Edwards. The EPA Comptox Chemistry Dashboard: a web-based data integration hub for Environmental Chemistry Data (SOT). Presented at Society of Toxicology, San Antonio, TX, March 11 - 15, 2018. https://doi.org/10.23645/epacomptox.5176750
Sullivan, K., N. Baker, S. Cochrane, S. Enoch, J. Ezendam, G. Patlewicz, E. Roggen, R. Settivari, AND K. Sewald. Towards an IATA for Chemical Respiratory Sensitization: Establishment of Reference Chemicals to Evaluate In Vitro and In Silico Approaches. Presented at 2018 SOT National Meeting, San Antonio, TX, March 11 - 15, 2018. https://doi.org/10.23645/epacomptox.6987158
Sayre, R. AND Chris Grulke. Universal LD50 predictions using deep learning. ICCVAM -Predictive Models for Acute Oral Systemic Toxicity, Bethesda, MD, April 11 - 12, 2018.
Richard, A., R. Lougee, Chris Grulke, K. Connors, K. Paul-Friedman, T. Shafer, J. Rathman, C. Yang, AND A. Williams. Use of ToxPrint chemotypes for exploring chemical feature enrichments across the ToxCast chemical-assay landscape. Society of Toxicology, San Antonio, TX, March 11 - 15, 2018.
Fitzpatrick, J., P. Pradeep, A. Karmaus, AND G. Patlewicz. Using Chemical and Biological Descriptors to Develop Predictive Models for Rat Acute Oral Toxicity. Presented at Society of Toxicology, San Antonio, TX, March 11 - 15, 2018. https://doi.org/10.23645/epacomptox.7029254
Karmaus, A., J. Fitzpatrick, D. Allen, G. Patlewicz, N. Kleinstreuer, AND W. Casey. Variability of LD50 Values from Rat Oral Acute Toxicity Studies: Implications for Alternative Model Development. Society of Toxicology, San Antonio, TX, March 11 - 15, 2018.