Science Inventory

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Winters, B., M. Madden, M. Angrish, M. Stiegel, T. Risby, AND J. Pleil. Standardization of exhaled breath condensate (EBC) collection using a feedback regulated breathing pattern. Society of Toxicology Meeting, New Orleans, LA, March 13 - 17, 2016.

Angrish, M., J. Pleil, M. Stiegel, M. Madden, Ginger Moser, AND D. Herr. Taxonomic applicability of inflammatory cytokines in adverse outcome pathway (AOP) development. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH - PART A: CURRENT ISSUES. Taylor & Francis, Inc., Philadelphia, PA, 79(4):184-196, (2016).

Pleil, J., J. Beauchamp, W. Miekisch, AND W. Funk. Adapting biomarker technologies to adverse outcome pathways (AOPs) research: current thoughts on using in vivo discovery for developing in vitro target methods. Journal of Breath Research. Institute of Physics Publishing, Bristol, Uk, 9(3):039001, (2015).

Pleil, J., M. Angrish, AND M. Madden. Adverse Outcome Pathways (AOPs) in Human Systems Biology: Gas-Phase Probes for Assessing In Vitro Enzyme System Perturbations. PITTCON Confererence & Expo 2015, New Orleans, LA, March 08 - 12, 2015.

Stiegel, M., J. Pleil, J. Sobus, M. Morgan, AND M. Madden. Analysis of inflammatory cytokines in human blood, breath condensate, and urine using a multiplex immunoassay platform. BIOMARKERS. Taylor & Francis, Inc., Philadelphia, PA, 20(1):35-46, (2015).

Pleil, J., M. Angrish, AND M. Madden. Human Exhaled Breath Condensate (EBC) Media: Implementation of Automated Quanterix SIMOA Immunochemistry Instrumentation. IABR Meeting, Vienna, AUSTRIA, September 13 - 16, 2015.

Pleil, J., M. Angrish, AND M. Madden. Immunochemistry for high-throughput screening of human exhaled breath condensate (EBC) media: implementation of automated quanterix SIMOA instrumentation. Journal of Breath Research. Institute of Physics Publishing, Bristol, Uk, 9(4):047108, (2015).

Angrish, M., M. Madden, AND J. Pleil. Inflammatory Cytokines as Preclinical Markers of Adverse Responses to Chemical Stressors. PittCon 2015, New Orleans, LA, March 08 - 12, 2015.

Stiegel, M., J. Pleil, J. Sobus, M. Angriish, AND M. Morgan. Kidney injury biomarkers and urinary creatinine variability in nominally healthy adults. BIOMARKERS. Taylor & Francis, Inc., Philadelphia, PA, 20:436-452, (2015).

Angrish, M., M. Madden, AND J. Pleil. Probe molecules (PrM) approach in adverse outcome pathway (AOP) based high throughput screening (HTS): in vivo discovery for developing in vitro target methods. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 2015(28):551-559, (2015).

Bean, H., J. Pleil, AND J. Hill. Report: New analytical and statistical approaches for interpreting the relationships among environmental stressors and biomarkers. BIOMARKERS. Taylor & Francis, Inc., Philadelphia, PA, 20(1):1-4, (2015).

Pleil, J. The Human Exposome and Systems Biology: Ongoing Empirical Measurement Studies and Biomarker Interpretation. Systems Biology for the Exposome Workshop, Atlanta, GA, May 27, 2015.

Pleil, J. Understanding new “exploratory” biomarker data: a first look at observed concentrations and associated detection limits. BIOMARKERS. Taylor & Francis, Inc., Philadelphia, PA, 20(2):168-169, (2015).

Funk, W., J. Pleil, D. Sauter, T. McDade, AND J. Holl. Use of Dried Blood Spots for Estimating Children?s Exposures to Heavy Metals in Epidemiological Research. Journal of Environmental & Analytical Toxicology. OMICS Publishing Group, LOS ANGELES , CA, 7:002, (2015).

Sobus, J., Rob Dewoskin, C. Tan, J. Pleil, M. Philips, BJ George, K. Christensen, D. Schreinemachers, M. Williams, E. Hubal, AND S. Edwards. Uses of NHANES biomarker data for chemical risk assessment: Trends, challenges and opportunities. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 123(10):919-927, (2015).

Sobus, J. AND J. Pleil. Using Spot Biomarker Data to Inform Chronic Exposure and Health Risk. 2015 ISES Annual Meeting, Henderson, NV, October 18 - 23, 2015.

Winters, B., M. Madden, M. Angrish, M. Stiegel, T. Risby, AND J. Pleil. Variability of exhaled breath condensate (EBC) volume and pH using a feedback regulated breathing pattern. Internat. Assoc. Breath Res, Vienna, AUSTRIA, September 14 - 16, 2015.

Lu, S., J. Sobus, G. Sallsten, M. Albin, J. Pleil, A. Gudmundsson, M. Madden, B. Strandberg, A. Wierzbicka, AND S. Rappaport. Are Urinary PAHs Biomarkers of Controlled Exposure to Diesel Exhaust? BIOMARKERS. Taylor & Francis, Inc., Philadelphia, PA, 19(4):332-9, (2014).

Stevens, T., M. Case, A. Rappold, J. Pleil, D. Diaz-Sanchez, W. Cascio, R. Devlin, AND M. Madden. Cardiovascular effects of diesel exhaust and ozone in a multi-pollutant context. Presented at Society of Toxicology, Phoenix, AZ, March 23 - 27, 2014.

Stiegel, M., J. Pleil, J. Sobus, AND M. Madden. Combining data visualization and statistical approaches for interpreting measurements and meta-data: Integrating heatmaps, variable clustering, and mixed regression models. Presented at American Chemical Society Meeting, San Francisco, CA, August 10 - 14, 2014.

Pleil, J., J. Sobus, M. Stiegel, D. Hu, K. Oliver, C. Olenick, M. Strynar, M. Clark, M. Madden, AND W. Funk. Estimating Common Parameters of Lognormally Distributed Environmental and Biomonitoring Data: Harmonizing Disparate Statistics from Publications. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH - PART B: CRITICAL REVIEWS. Taylor & Francis, Inc., Philadelphia, PA, 17(6):341-368, (2014).

Andersen, E., J. Sobus, M. Strynar, J. Pleil, AND S. Nakayama. Evaluating an alternative method for rapid urinary creatinine determination. CLINICAL CHEMISTRY. American Association of Clinical Chemistry, Washington, DC, 77(18):1114-1123, (2014).

Pleil, J., M. Stigel, AND K. Fent. Exploratory breath analyses for assessing toxic dermal exposure of firefighters during suppression of structural burns. Journal of Breath Research. Institute of Physics Publishing, Bristol, Uk, 8(3):1752-7163, (2014).

Pleil, J., W. Miekisch, M. Stiegel, AND J. Beauchamp. Extending breath analysis to the cellular level: current thoughts on the human microbiome and the expression of organic compounds in the human exposome. Journal of Breath Research. Institute of Physics Publishing, Bristol, Uk, 8(2):029001, (2014).

Angrish, M., M. Madden, AND J. Pleil. Gas Phase Probe Molecules for Assessing In vitro Metabolism to Infer an In vivo Response. EPA's Chemical Safety Research: Second ToxCast Data Summit, Research Triangle Park, NC, September 29 - 30, 2014.