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Records 101 to 149 of 149

2010
COHEN-HUBAL, E. A., A. M. RICHARD, L. AYLWARD, S. W. EDWARDS, J. GALLAGHER, M. GOLDSMITH, S. ISUKAPALLI, R. TORNERO-VELEZ, E. J. WEBER, AND R. J. KAVLOCK. Advancing Exposure Characterization for Chemical Evaluation and Risk Assessment. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH - PART B: CRITICAL REVIEWS. Taylor & Francis, Inc., Philadelphia, PA, 13(2):299-313, (2010).
COHEN-HUBAL, E. A., A. M. RICHARD, L. Aylward, S. W. EDWARDS, J. GALLAGHER, M. GOLDSMITH, S. Isukapalli, R. TORNERO-VELEZ, E. J. WEBER, AND R. J. KAVLOCK. Advancing Exposure Characterization for Chemical Evaluation and Risk Assessment . JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH - PART B: CRITICAL REVIEWS. Taylor & Francis, Inc., Philadelphia, PA, 13(2-4):299-313, (2010).
Kim, K., S. S. Anand, H. J. Kim, C. A. White, J. W. FISHER, R. TORNERO-VELEZ, AND J. V. BRUCKNER. Age, Dose, and Time-Dependency of Plasma and Tissue Distribution of Deltamethrine in Immature Rats. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 115(2):354-368, (2010).
Zhang, X., J. B. KNAAK, R. TORNERO-VELEZ, J. N. BLANCATO, AND C. C. DARY. Application of Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling in Cumulative Risk Assessment for N-Methyl Carbamate Insecticides. Third, Chapter 73, Robert Krieger (ed.), Handbook of Pesticide Toxicology. Elsevier Ltd, Oxford, Uk, 2:1591-1605, (2010).
TORNERO-VELEZ, R., A. Mirfazaelian, K. Kim, S. S. Anand, H. J. Kim, W. HAINES, J. V. BRUCKNER, AND J. W. FISHER. Evaluation of Deltamethrin Kinetics and Dosimetry in the Maturing Rat using a PBPK Model. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, 244(2):208-217, (2010).
GOLDSMITH, M., T. R. Transue, D. CHANG, R. TORNERO-VELEZ, AND C. C. DARY. PAVA: Physiological and Anatomical Visual Analytics for Mapping of Tissue-Specific Concentration and Time-Course Data. JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS. Springer, New York, NY, 37(3):277-287, (2010).
Godin, S. J., M. J. DEVITO, M. F. HUGHES, D. G. ROSS, J. M. STARR, R. W. SETZER, R. CONOLLY, R. TORNERO-VELEZ, AND E. J. Scollon. Physiologically based pharmacokinetic modeling of deltamethrin: Development of a rat and human diffusion-limited model. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 115(2):330-343, (2010).
DAVIS, J., R. TORNERO-VELEZ, AND R. W. SETZER. Quantifying uncertainty in Bayesian calibrated animal-to-human PBPK models with informative prior distributions. Presented at Air Force Institute of Technology (AFIT) Department of Mathematics and Statistics, Dayton, OH, May 20, 2010.
2009
SETZER, R. W., J. DAVIS, R. TORNERO-VELEZ, J. XUE, AND V. G. ZARTARIAN. Applying Uncertainty Analysis to a Risk Assessment for the Pesticide Permethrin. Presented at Computational Toxicology Board of Scientific Counselors Review, RTP, NC, September 29 - 30, 2009.
TAN, C., E. J. WEBER, J. F. KENNEKE, M. K. MORGAN, D. CHANG, M. GOLDSMITH, R. TORNERO-VELEZ, AND C. C. DARY. Computational Approaches and Tools for Exposure Prioritization and Biomonitoring Data Interpretation. Presented at Computational Toxicology Board of Scientific Counselors Review, RTP, NC, September 29 - 30, 2009.
2008
SCOLLON, E., J. M. STARR, M. F. HUGHES, R. TORNERO-VELEZ, H. M. WHEELER, D. G. ROSS, AND M. J. DEVITO. DOSE-DEPENDENT DISTRIBUTION AND ELIMINATION OF CIS- AND TRANS-PERMETHRIN IN THE RAT. Presented at Society of Toxicology Annual Meeting, Seattle, WA, March 16 - 20, 2008.
GODIN, S., R. TORNERO-VELEZ, E. SCOLLON, D. G. ROSS, M. F. HUGHES, R. CONOLLY, AND M. J. DEVITO. PBPK MODELING OF DELTAMETHRIN IN RATS. Presented at Society of Toxicology Annual Meeting, Seattle, WA, March 16 - 20, 2008.
2007
LEE, J. S., D. C. WOLF, J. W. ALLEN, W. O. WARD, R. TORNERO-VELEZ, M. J. DEVITO, AND C. CORTON. BUILDING REALISTIC BIOLOGICALLY-BASED PHARMACOKINETIC MODELS FOR PREDICTING SUSCEPTIBILITY IN THE AGED POPULATIONS. Presented at International Science Forum on Computational Toxicology, RTP, NC, May 21 - 23, 2007.
POWER, F. W., C. C. DARY, J. B. KNAAK, R. TORNERO-VELEZ, AND J. N. BLANCATO. MALATHION EXPOSURE DURING LICE TREATMENT: USE OF EXPOSURE RELATED DOSE ESTIMATING MODEL (ERDEM) AND FACTORS RELATING TO THE EVALUATION OF RISK. U.S. Environmental Protection Agency, Washington, DC, EPA/600/R-07/023 (NTIS PB2007-106971), 2007.
TORNERO-VELEZ, R., E. SCOLLON, J. M. STARR, M. F. HUGHES, M. J. DEVITO, AND C. C. DARY. PHARMACOKINETIC/PHARMACODYNAMIC MODELING OF PERMETHRIN IN THE RAT. Presented at 2007 Society of Toxicology Annual Meeting, Charlotte, NC, March 25 - 29, 2007.
2006
CHANG, D., T. L. WHITEHEAD, M. S. OKINO, C. S. MAZUR, J. F. KENNEKE, R. TORNERO-VELEZ, J. C. JOHNSON, AND C. C. DARY. AN IN SILICO INVESTIGATION OF THE ENANTIOSELECTIVE METABOLISM RATES OF TRIAZOLE FUGICIDES. Presented at 14th North American International Society for the Study of Xenobiotics Meeting, Rio Grande, PUERTO RICO, October 22 - 26, 2006.
MIRFAZAELIAN, A., K. KIM, S. S. ANAND, H. J. KIM, R. TORNERO-VELEZ, J. V. BUCKNER, AND J. W. FISHER. DEVELOPMENT OF A PHYSIOLOGICALLY BASED PHARMACOKINETIC MODEL FOR DELTAMETHRIN IN ADULT AND DEVELOPING SPRAGUE-DAWLEY RATS. Presented at Society of Toxicology, San Diego, CA, March 05 - 09, 2006.
MIRFAZAELIAN, A., K. KIM, S. S. ANAND, S. LEE, H. J. KIM, R. TORNERO-VELEZ, J. V. BRUCKNER, AND J. W. FISHER. DEVELOPMENT OF A PHYSIOLOGICALLY BASED PHARMACOKINETIC MODEL FOR DELTAMETHRIN IN DEVELOPING SPRAGUE-DAWLEY RATS. Presented at Society of Toxicology, San Diego, CA, March 05 - 09, 2006.
MIRFAZAELIAN, A., K. KIM, S. S. ANAND, H. J. KIM, R. TORNERO-VELEZ, J. V. BRUCKNER, AND J. W. FISHER. DEVELOPMENT OF A PHYSIOLOGICALLY BASED PHARMACOKINETIC MODEL FOR DELTAMETHRIN IN THE ADULT MALE SPRAGUE-DAWLEY RAT. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 93(2):432-442, (2006).
TORNERO-VELEZ, R., J. XUE, E. SCOLLON, J. M. STARR, P. P. EGEGHY, D. B. BARR, M. J. DEVITO, AND C. C. DARY. DIETARY EXPOSURE TO PYRETHROIDS IN THE U.S POPULATION. Presented at ISEA/ISEE 2006, Paris, FRANCE, September 02 - 06, 2006.
CHANG, D., M. S. OKINO, FRED W. POWER, R. TORNERO-VELEZ, J. F. KENNEKE, CHRIS S. MAZUR, C. C. DARY, AND TIM W. COLLETTE. ESTIMATION OF CHEMICAL SPECIFIC PARAMETERS WITHIN PHYSIOLOGICALLY BASED PHARMACOKINETIC/PHARMACODYNAMIC MODELS. Presented at EPA Science Forum 2006, Washington, DC, May 16 - 18, 2006.
CHANG, D., P. P. EGEGHY, J. B. KNAAK, R. TORNERO-VELEZ, M. S. OKINO, F. W. POWER, M. DELLARCO, C. S. MAZUR, J. F. KENNEKE, AND C. C. DARY. INFLUENCE OF MATRIX FORMULATION ON DERMAL PERCUTANEOUS ABSORPTION OF TRIAZOLE FUNGICIDES USING QSAR AND PBPK / PD MODELS. Presented at ISEA/ISEE 2006 , Paris, FRANCE, September 02 - 06, 2006.
PASQUINELLI, M., R. TORNERO-VELEZ, AND J. R. RABINOWITZ. MOLECULAR MODELS OF PARATHYROID METABOLISM BY CARBOXYLESTERASES: DIFFERENTIAL EFFECTS DUE TO STEREOCHEMISTRY. Presented at BOARD OF SCIENTIFIC COUNSELORS (BOSC), RTP, NC, June 19 - 20, 2006.
WOLANSKY, M., M. J. DEVITO, R. TORNERO-VELEZ, M. F. HUGHES, H. A. OZKAYNAK, T. J. SHAFER, C. J. GORDON, J. HARRILL, AND K. M. CROFTON. TESTING STRATEGIES TO ESTIMATE NEUROTOXIC RISK FOR CUMULATIVE EXPOSURE TO PYRETHROID MIXTURES. Presented at Society for Risk Analysis, Baltimore, MD, December 03 - 06, 2006.
OKINO, M. S., C. B. THOMPSON, F. W. POWER, R. TORNERO-VELEZ, A. TSANG, J. N. BLANCATO, AND C. C. DARY. URINARY BIOMARKER INTERPRETATION USING PHARMACOKINETIC MODELS. Presented at International Council of Chemistry Associations Workshop, Minneapolis, MN, July 26 - 27, 2006.
2005
Evans, M V., R. TORNERO-VELEZ, M J. DeVito, M S. Okino, A M. Geller, J N. Blancato, AND L S. Birnbaum. DEVELOPMENT OF A PHYSIOLOGICALLY BASED PHARMOKINETICS (PBPK) MODEL TO COMPARE DIFFERENCES IN DISPOSITION OF TRICHLOROETHYLENE (TCE) IN ADULT VERSUS ELDERLY RATS. Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 06 - 10, 2005.
KNAAK, J. B., D. CHANG, C. C. DARY, R. TORNERO-VELEZ, M. S. OKINO, AND FRED W. POWER. ESTIMATION OF ADIPOSE TISSUE; BLOOD PARTITION COEFFICIENTS OF CARBAMATES AND ORGANOPHOSPHORUS PESTICIDES USING RELATIVE LIPID CONTENT AND LOGP AS THE MECHANISTIC DETERMINANTS. Presented at American Chemical Society Meeting and Exposition, Washington, DC, August 27 - September 01, 2005.
OKINO, M. S., M. V. EVANS, S. ISUKAPALLI, S. WANG, P. G. GEORGOPOULOS, M. KARSTADT, R. TORNERO-VELEZ, M. DEVITO, L. S. BIRNBAUM, J. N. BLANCATO, AND A. M. GELLER. EVALUATING RISK IN OLDER ADULTS USING PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELS. Presented at EPA Science Forum 2005, Washington, DC, May 16 - 18, 2005.
Granville, C. A., M. K. Ross, R TORNERO-VELEZ, N. M. Hanley, A. Gold, A M. Richard, K. Funasaka, A H. Tennant, A D. Kligerman, M V. Evans, AND D M. Demarini. GENOTOXICITY AND METABOLISM OF THE SOURCE-WATER CONTAMINANT 1,1-DICHLOROPROPENE: ACTIVATION BY GSTT1-1 AND STRUCTURE-ACTIVITY CONSIDERATIONS. MUTATION RESEARCH. Elsevier Science BV, Amsterdam, Netherlands, 572(1-2):98-112, (2005).
Scollon, E. J., M F. Hughes, M J. DeVito, R. TORNERO-VELEZ, AND S. J. Godin. IN VITRO ESTIMATES OF METABOLIC PARAMETERS AND THEIR USE IN PREDICTIVE PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELING (PBPK) OF THE TYPE I PYRETHROIDS PERMETHRIN AND BIFENTHRIN. Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 06 - 10, 2005.
BENCIC, D. C., A. D. BIALES, R. W. FLICK, E. R. WAITS, TIM COLLETTE, D. GETER, M. OKINO, AND R. TORNERO-VELEZ. LINKING 'OMIC AND GENETIC DATA TO PHYSIOLOGICALLY-BASED PHARMACOKINETIC AND PHARMACODYNAMIC MODELING TO ENHANCE ECOLOGICAL AND HUMAN HEALTH RISK ASSESSMENT. Presented at 2005 EPA Science Forum, Washington, DC, May 16 - 18, 2005.
Godin, S. J., R. TORNERO-VELEZ, E. J. Scollon, M F. Hughes, AND M J. DeVito. PREDICTIVE PHYSIOLOGICALLY BASED PHARMACOKINETICS MODELING (PBPK) OF PYRETHROID PESTICIDES. Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 06 - 10, 2005.
OKINO, M. S., W. CHIU, M. V. EVANS, F. W. POWER, J. C. LIPSCOMB, R. TORNERO-VELEZ, C. C. DARY, J. N. BLANCATO, C. CHEN, AND L. S. BIRNBAUM. SUITABILITY OF USING IN VITRO AND COMPUTATIONALLY ESTIMATED PARAMETERS IN SIMPLIFIED PHARMACOKINETIC MODELS. Presented at North American ISSX Meeting , Maui, HI, October 23 - 27, 2005.
OKINO, M. S., F. W. POWER, J. B. KNAAK, R. TORNERO-VELEZ, C. LUNCHICK, A. LOWIT, J. N. BLANCATO, AND C. C. DARY. USE OF A PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODEL TO ESTIMATE ABSORBED CARBARYL DOSE IN CHILDREN AFTER TURF APPLICATION. Presented at Socieity of Toxicology Annual Meeting, New Orleans, LA, March 06 - 10, 2005.
POWER, F. W., J. B. KNAAK, M. S. OKINO, R. TORNERO-VELEZ, J. N. BLANCATO, AND C. C. DARY. USE OF EXPOSURE-RELATED DOSE ESTIMATING MODEL (ERDEM) FOR ASSESSMENT OF AGGREGATE EXPOSURE OF INFANT AND CHILDREN TO N-METHYL CARBAMATE INSECTICIDES. Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 06 - 10, 2005.
TORNERO-VELEZ, R., N. S. TULVE, M. S. OKINO, AND C. C. DARY. USE OF PBPK MODELING TO ASSESS CYPERMETHRIN EXPOSURE IN YOUNG AFTER A RESIDENTIAL APPLICATION. Presented at International Society of Exposure Analysis Conference, Tucson, AZ, October 30 - November 03, 2005.
2004
TORNERO-VELEZ, R, C C. Dary, M Dellarco, AND J Blancato. A PBPK MODEL OF PYRETHROID PESTICIDES FOR APPLICATION IN RISK ASSESSMENT. Presented at Exposure Assessment in a Changing Environment, Utrecht, The Netherlands, June 16-18, 2004.
Dary, C C., M Dellarco, J N. Blancato, AND R. TORNERO-VELEZ. A PRELIMINARY PBPK MODEL OF PYRETHROID PESTICIDES FOR APPLICATION IN ENVIRONMENTAL RISK ASSESSMENT. Presented at X2004 - Exposure Assessment in a Changing Environment, Utrecht, The Netherlands, June 16-18, 2004.
TORNERO-VELEZ, R, W. Longest, S. Harper, C C. Dary, AND J Blancato. ADVANCED COMPUTATIONAL METHODS IN DOSE MODELING: APPLICATION OF COMPUTATIONAL BIOPHYSICAL TRANSPORT, COMPUTATIONAL CHEMISTRY, AND COMPUTATIONAL BIOLOGY. Presented at EPA Science Forum 2004, Washington, DC, June 1-3, 2004.
Blancato, J, C C. Dary, M S. Okino, F W. Power, A. Ruiz, AND R. TORNERO-VELEZ. APPLICATION OF ERDEM IN RISK ASSESSMENT: HEALTH EFFECTS DIVISION'S RISK ASSESSOR TRAINING AND CERTIFICATION PROGRAM. Presented at Health Effects Division's Risk Assessor Training and Certification Program, Washington, DC, August 11-12, 2004.
Evans, M V., F W. Power, C C. Dary, R. TORNERO-VELEZ, AND J. Blancato. APPLICATION OF THE EXPOSURE DOSE ESTIMATING MODEL (ERDEM) TO ASSESSMENT OF DERMAL EXPOSURE IN THE RAT TO MALATHION. Presented at Society of Toxicology, Baltimore, MD, March 21-25, 2004.
TORNERO-VELEZ, R., M. K. Ross, C. A. Granville, J. Laskey, J. P. Jones, D M. DeMarini, AND M V. Evans. METABOLISM AND MUTAGENICITY OF SOURCE WATER CONTAMINANTS 1, 3-DICHLOROPROPANE AND 2,2-DICHLOROPROPANE. DRUG METABOLISM AND DISPOSITION 32(1):123-131, (2003).
Ross, M. K., R TORNERO-VELEZ, C. Granville, A. Gold, M V. Evans, AND D M. DeMarini. METABOLISM OF 1,1- AND 1,3- DICHLOROPROPENE: A MECHANISM OF BIOACTIVATION BY GLUTATHIONE. Presented at International Society for the Study of Xenobiotics, Vancouver, Canada, August 29-September 2, 2004.
TORNERO-VELEZ, R, H. Nichols, M V. Evans, M J. DeVito, M J. DeVito, M Dellarco, J N. Blancato, AND K. G. Anlauf. TOWARDS A GENERIC PBPK MODEL OF PYRETHROID PESTICIDES: MODELING DELTAMETHRIN AND PERMETHIN IN THE RAT. Presented at 43rd Annual Meeting of the Society of Toxicology, Baltimore, MD, March 21-25, 2004.
TORNERO-VELEZ, R, H P. Nichols, M V. Evans, M J. DeVito, C C. Dary, M Dellarco, AND J Blancato. TOWARDS A GENERIC PBPK MODEL OF PYRETHROID PESTICIDES: MODELING DELTAMETHRIN AND PERMETHRIN IN THE RAT. Presented at Society of Toxicology, Baltimore, MD, March 21-25, 2004.
2003
TORNERO-VELEZ, R, C C. Dary, J. B. Knaak, F W. Power, AND M Dellarco. A COMPARATIVE INVESTIGATION OF THE INFLUENCE OF DERMAL APPENDAGES (HAIR FOLLICLES) ON THE PERCUTANEOUS ABSORPTION OF ORGANOPHOSPHORUS (OP) INSECTICIDES USING QSAR AND PBPK/PD MODELS FOR HUMAN RISK ASSESSMENT. Presented at International Society of Exposure Analysis, Stresa, Italy, September 21-25, 2003.
Knaak, J. B., R TORNERO-VELEZ, F W. Power, J N. Blancato, AND C C. Dary. BETTER EXPOSURE-DOSE MODELS FOR PESTICIDES. Presented at Science Forum 2003, Washington, DC, May 5-7, 2003.
TORNERO-VELEZ, R., J. Laskey, AND M V. Evans. IN VITRO DETERMINATION OF KINETIC CONSTANTS FOR 1,3-DICHLOROPROPANE, 2,2-DICHLOROPROPANE, AND 1,1-DICHLOROPROPENE IN RAT LIVER MICROSOMES AND CYTOSOL. Presented at Society of Toxicology, Salt Lake City, UT, March 9-13, 2003.
1997
Lindstrom, A B., K. YeowellO'Connell, S. Waidyanatha, B. T. Golding, R TORNERO-VELEZ, AND S. M. Rappaport. MEASUREMENT OF BENZENE OXIDE IN THE BLOOD OF RATS FOLLOWING ADMINISTRATION OF BENZENE. CARCINOGENESIS 18(8):1637-1641, (1997).