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Records 1 to 66 of 66

2024
Brennan, A., D. Chang, J. Cowden, S. Davidson-Fritz, J. Dean, M. Devito, J. Ford, L. Everett, A. Harrill, S. Hester, M. Hughes, J. Lambert, L. Lizarraga, R. Mezencev, D. Macmillan, G. Patlewicz, Kristina Chialton, R. Thomas, K. Vitense, L. Wehmas, A. Renyer, S. Auerbach, AND W. Casey. EPA Transcriptomic Assessment Product (ETAP) for Perfluoro-3-Methoxypropanoic Acid. U.S. Environmental Protection Agency, Washington, DC, EPA/600/X-24/066, 2024. https://doi.org/10.23645/epacomptox.25352962
Chang, D., J. Cowden, S. Davidson-Fritz, J. Dean, M. Devito, L. Everett, A. Harrill, S. Hester, M. Hughes, J. Lambert, L. Lizarraga, R. Mezencev, G. Patlewicz, R. Thomas, L. Wehmas, K. Vitense, S. Auerbach, W. Casey, R. Sams, S. Hunter, J. Bucher, T. Buckley, P. Egeghy, K. Paul-Friedman, J. Harrill, K. Isaacs, R. Judson, J. Kaiser, S. Masten, F. Parham, D. Petersen, A. Phillips, J. Sobus, Dan Villeneuve, P. White, A. Williams, G. Woodall, AND J. Zhao. Scientific Studies Supporting Development of Transcriptomic Points of Departure for EPA Transcriptomic Assessment Products (ETAPs). U.S. Environmental Protection Agency, Washington, DC, EPA/600/X-23/084, 2024. https://doi.org/10.23645/epacomptox.25365550
Brennan, A., D. Chang, J. Cowden, S. Davidson-Fritz, J. Dean, M. Devito, J. Ford, L. Everett, A. Harrill, S. Hester, M. Hughes, J. Lambert, L. Lizarraga, R. Mezencev, D. Macmillan, G. Patlewicz, K. Thayer, R. Thomas, K. Vitense, L. Wehmas, A. Renyer, S. Auerbach, W. Casey, R. Sams, S. Hunter, W. Cascio, K. Holt, S. Jones, R. Subramaniam, G. Rice, J. Bucher, T. Buckley, P. Egeghy, K. Paul-Friedman, J. Harrill, K. Isaacs, R. Judson, J. Kaiser, S. Masten, F. Parham, D. Petersen, A. Phillips, J. Sobus, Dan Villeneuve, P. White, A. Williams, G. Woodall, AND J. Zhao. Standard Methods for Development of EPA Transcriptomic Assessment Products (ETAPs). U.S. Environmental Protection Agency, Washington, DC, EPA/600/X-23/083, 2024. https://doi.org/10.23645/epacomptox.25365496
2023
Nyffeler, J., C. Willis, F. Harris, M. Foster, B. Chambers, M. Culbreth, R. Brockway, S. Davidson-Fritz, D. Dawson, I. Shah, K. Paul-Friedman, D. Chang, L. Everett, J. Wambaugh, G. Patlewicz, AND J. Harrill. Application of Cell Painting for chemical hazard evaluation in support of screening-level chemical assessments. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, 468:116513, (2023). https://doi.org/10.1016/j.taap.2023.116513
Adams, M., H. Hilde, D. Chang, A. Richard, A. Williams, I. Shah, AND G. Patlewicz. Development of a CSRML version of the Analog identification Methodology (AIM) fragments and their evaluation within the Generalised Read-Across (GenRA) approach. Computational Toxicology. Elsevier B.V., Amsterdam, Netherlands, 25:100256, (2023). https://doi.org/10.1016/j.comtox.2022.100256
Lowe, C., N. Charest, C. Ramsland, D. Chang, T. Martin, AND A. Williams. Transparency in Modeling through Careful Application of OECD’s QSAR/QSPR Principles via a Curated Water Solubility Data Set. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 36(3):465-478, (2023). https://doi.org/10.1021/acs.chemrestox.2c00379
Charest, N., C. Lowe, D. Chang, C. Ramsland, T. Martin, AND A. Williams. Transparency in QSXR Modeling: Modernizing to a Machine Learning Paradigm. QSAR, Copenhagen, DENMARK, June 05 - 09, 2023. https://doi.org/10.23645/epacomptox.23279843.v1
Charest, N., C. Lowe, D. Chang, C. Ramsland, T. Martin, AND A. Williams. Transparency in QSXR Modeling: Modernizing to a Machine Learning Paradigm (ACS 2023). ACS, San Francisco, CA, August 13 - 17, 2023. https://doi.org/10.23645/epacomptox.23823828
Chang, D., K. Fay, K. Mansouri, K. Markey, J. Prindiville, G. Patlewicz, M. Lewis, M. Shobair, E. Saluck, AND A. Richard. Use of Supervised Learning Approaches with Hierarchical Fragment-based Representations (ToxPrints) to Characterize Mode-of-Action in Aquatic Fish Toxicity. SERMACS, Durham, NC, October 25 - 28, 2023. https://doi.org/10.23645/epacomptox.24790593
2022
Harten, P., T. Martin, D. Chang, AND D. Young. Finding Potential Replacements for TRI Solvents Using the Environmental Impact of the Average Solvent. JOURNAL OF SOLUTION CHEMISTRY. Plenum Press, New York, NY, 51:838-849, (2022). https://doi.org/10.1007/s10953-022-01174-y
2021
Shobair, Mahmoud A., Chris Grulke, D. Chang, R. Lougee, K. Paul-Friedman, AND A. Richard. Combining in silico structure-based methods and enrichment analysis to increase confidence in HTS results: Application to Tox21 TRHR assay. Society of Toxicology 2021 Virtual Annual Meeting, RTP, NC, March 12 - 26, 2021. https://doi.org/10.23645/epacomptox.14474052
Yun, Y., R. Tornero-Velez, Tom Purucker, D. Chang, AND A. Edginton. Evaluation of Quantitative Structure Property Relationship algorithms for predicting plasma protein binding in humans. Computational Toxicology. Elsevier B.V., Amsterdam, Netherlands, 17:100142, (2021). https://doi.org/10.1016/j.comtox.2020.100142
Nyffeler, J., C. Willis, M. Culbreth, Richard E. Brockway, L. Everett, G. Patlewicz, I. Shah, D. Chang, J. Wambaugh, K. Paul-Friedman, AND J. Harrill. High-throughput phenotypic profiling within the NAMs-based, tiered hazard evaluation strategy at the U.S. Environmental Protection Agency (EuroTox 2021). EUROTOX congress 2021, virtual, NC, September 26 - October 01, 2021. https://doi.org/10.23645/epacomptox.16838164
Nyffeler, J., C. Willis, G. Patlewicz, D. Chang, I. Shah, AND J. Harrill. Identifying putative mode-of-actions for environmental chemicals using high-throughput phenotypic profiling (WC11). 11th World Conference on Alternatives and Animal Use in the Life Science (WC11), Virtual, NC, NETHERLANDS, August 23 - September 02, 2021. https://doi.org/10.23645/epacomptox.16837921
Shobair, Mahmoud A., D. Chang, R. Lougee, K. Paul-Friedman, Chris Grulke, J. Zhao, R. Huang, M. Xia, AND A. Richard. In silico and cheminformatics enrichment analysis to increase confidence in in vitro high-throughput screening (HTS) results: Application to Tox21 thyrotropin-releasing hormone receptor (TRHR) assay. QSAR 2021 International Workshop on QSAR in Environmental and Health Sciences, Virtual, NC, June 07 - 10, 2021. https://doi.org/10.23645/epacomptox.15101949
Fay, K., K. Mansouri, J. Prindiville, G. Patlewicz, M. Lewis, A. Richard, M. Shobair, E. Saluck, AND D. Chang. Revisiting and Updating Chemical Categorizations using chemical fingerprint and High-Throughput Screening Data (QSAR 2021). QSAR 2021 International Workshop on QSAR in Environmental and Health Sciences, Virtual, NC, June 07 - 10, 2021. https://doi.org/10.23645/epacomptox.15899004
Goldsmith, M., J. Kroemer, S. Pokhrel, D. Chang, G. Fortin, AND A. Deschenes. Toward Playbooks, Workflows and Federated Models for Agrochemical Discovery and De-risking. Chapter 9, Rauzan & Lorsbach (ed.), Crop Protection Products for Sustainable Agriculture. ACS Publications, Washington, DC, , 181-200, (2021).
2020
Nyffeler, J., C. Willis, M. Culbreth, Richard E. Brockway, L. Everett, G. Patlewicz, I. Shah, D. Chang, J. Wambaugh, K. Paul-Friedman, AND J. Harrill. Applications of image-based high-throughput phenotypic profiling (HTPP) for hazard evaluation of environmental chemicals. Intelligent Systems for Molecular Biology, NA, NC, July 13 - 16, 2020. https://doi.org/10.23645/epacomptox.12765221
Nyffeler, J., C. Willis, M. Culbreth, Richard E. Brockway, L. Everett, G. Patlewicz, I. Shah, D. Chang, J. Wambaugh, K. Paul-Friedman, AND J. Harrill. Image-based high-throughput phenotypic profiling for hazard evaluation of environmental chemicals: Two applications. OpenTox 2020 Virtual Conference, Durham, NC, September 21 - 25, 2020. https://doi.org/10.23645/epacomptox.13269335
Shobair, Mahmoud A., Chris Grulke, D. Chang, R. Lougee, K. Paul-Friedman, AND A. Richard. Integrating in silico and in vitro data for New Approach Methods evaluation: Application to Tox21 TRHR assay results. The American Society for Cellular and Computational Toxicology (ASCCT) 2020 annual meeting, DURHAM, North Carolina, October 21 - 22, 2020. https://doi.org/10.23645/epacomptox.13148168
Shobair, Mahmoud A., D. Chang, Chris Grulke, K. Paul-Friedman, AND A. Richard. Integrating in silico and in vitro data to identify putative thyrotropin-releasing hormone receptor ligands. ACS Fall meeting, acs.org, San Francisco, California, August 16 - 20, 2020. https://doi.org/10.23645/epacomptox.12822230
Fay, K., K. Markey, K. Mansouri, J. Prindiville, G. Patlewicz, A. Richard, R. Lougee, Mahmoud A. Shobair, M. Lewis, E. Saluck, AND D. Chang. Revisiting and Updating Chemical Categorizations using chemical fingerprint and High-Throughput Screening Data - ACS 2020. ACS, San Francisco, California, August 16 - 20, 2020. https://doi.org/10.23645/epacomptox.12830594
Chang, D., K. Fay, K. Markey, M. Phillips, G. Patlewicz, A. Richard, L. Scarano, Mahmoud A. Shobair, R. Lougee, E. Saluck, J. Prindiville, C. Inglis, M. Lewis, AND K. Mansouri. Revisiting and updating chemical groupings with new approach methodologies. APCRA-5 Virtual Teleconference (Accelerating the Pace of Chemical Risk Assessment), Virtual, Virtual, August 26 - 27, 2020. https://doi.org/10.23645/epacomptox.13268963
Fay, K., K. Markey, K. Mansouri, J. Prindiville, G. Patlewicz, A. Richard, R. Lougee, Mahmoud A. Shobair, M. Lewis, E. Saluck, AND D. Chang. Revisiting and updating chemical groupings with new approach methodologies (Presentation by Dan Chang). ICCVAM RAWG, Virtual, Virtual, May 29, 2020. https://doi.org/10.23645/epacomptox.12564074
2019
Otter, R., M. Embry, M. Barron, A. Beasley, S. Belanger, M. Bonnell, J. Brill, D. Chang, K. Connors, D. DeZwart, K. Fay, M. Halder, S. Hughes, A. Kienzler, T. Norberg-King, H. Sanderson, N. Vallotton, AND P. Wilson. EnviroTox database: Overview and applications. SETAC North America, Toronto, ON, CANADA, November 03 - 07, 2019.
2018
Leonard, J., C. Stevens, K. Mansouri, D. Chang, H. Pudukodu, S. Smith, AND C. Tan. A Workflow for Identifying Metabolically Active Chemicals to Complement in vitro Toxicity Screening. Computational Toxicology. Elsevier B.V., Amsterdam, Netherlands, 6:71-83, (2018).
Embry, M., M. Barron, A. Beasley, S. Belanger, J. Brill, D. Chang, D. De Zwart, M. Halder, S. Hughes, A. Kienzler, T. Norberg-King, R. Otter, H. Sanderson, AND P. Wilson. Ecological Threshold for Toxicological Concern (eco-TTC) - applications for environmental risk assessment in various contexts. SETAC North America, Sacramento, CA, November 04 - 08, 2018.
Phillips, K., K. Isaacs, D. Chang, AND K. Markey. Evaluation of High-throughput Chemical Functional Use Models (ISES Annual Meeting). ISES-ISEE 2018 Joint Annual Meeting, Ottawa, Ontario, CANADA, August 26 - 30, 2018.
2017
Leonard, J., D. Chang, H. El-Masri, S. Edwards, C. Stevens, K. Mansouri, P. Egeghy, AND C. Tan. A tiered approach for integrating exposure and dosimetry with in vitro dose-response data in the modern risk assessment paradigm. 254th ACS National Meeting & Exposition, Washington, DC, August 20 - 24, 2017.
Grulke, Chris, Rocky Goldsmith, R. Brooks, D. Chang, C. Tan, R. Tornero-Velez, AND K. Holm. Enabling PBPK model development through the application of freely available techniques for the creation of a chemically-annotatedcollection of literature. Presented at American Chemical Society, San Francisco, CA, August 10 - 14, 2014.
Leonard, J., C. Stevens, K. Mansouri, D. Chang, AND C. Tan. Identifying Metabolically Active Chemicals Using a Consensus Quantitative Structure Activity Model for Estrogen Receptor Binding. SOT Annual Meeting, Baltimore, MD, March 12 - 16, 2017.
Leonard, J., C. Stevens, K. Mansouri, D. Chang, AND C. Tan. Identifying Metabolically Active Chemicals Using a Consensus Quantitative Structure Activity Relationship Model for Estrogen Receptor Binding. Opentox USA 2017, Durham, NC, July 12 - 13, 2017.
Williams, A., Chris Grulke, D. Chang, K. Markey, AND J. Edwards. The EPA CompTox Dashboard and Underpinning Software Architecture – a platform for data integration for environmental chemistry data (ACS Fall Meeting 7 of 12). Presented at ACS Fall Meeting, Washington, DC, August 20 - 24, 2017.
2016
Phillips, M., J. Leonard, Chris Grulke, D. Chang, S. Edwards, R. Brooks, M. Goldsmith, H. El-Masri, AND C. Tan. A Workflow to Investigate Exposure and Pharmacokinetic Influences on High-Throughput in Vitro Chemical Screening Based on Adverse Outcome Pathways. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 124(1):53-60, (2016).
Lu, J., M. Goldsmith, Chris Grulke, D. Chang, J. Leonard, E. Hypes, AND C. Tan. A comprehensive physiologically based pharmacokinetic knowledgebase and web-based interface for rapid model ranking and querying. Society of Toxicology 55th Annual Meeting and ToxExpo, New Orleans, LA, March 13 - 17, 2016.
Tan, C., J. Leonard, S. Scholle, M. Winter, P. Key, J. Lu, AND D. Chang. Evaluating the Value of Augmenting In Vitro Hazard Assessment with Exposure and Pharmacokinetics Considerations for Chemical Prioritization. Society of Toxicology Conf, New Orleans, LA, March 13 - 17, 2016.
2015
Goldsmith, M., D. Chang, A. Deschenes, K. Phillips, K. Isaacs, AND J. Wambaugh. Quantitative structure-Functional Ingredient Relationships (qFIRs): Development of a data-driven workflow for alternatives ingredient assessments for in silico molecular repurposing. American Chemical Society National Meeting, Boston, MA, August 16 - 20, 2015.
2014
Tan, C., D. Chang, M. Phillips, S. Edwards, Chris Grulke, Rocky Goldsmith, J. Sobus, R. Conolly, R. Tornero-Velez, AND C. Dary. Biomarkers in Computational Toxicology. Chapter 63, Biomarkers in Toxicology. Elsevier, Shannon, Ireland, , 1039-1055, (2014).
Goldsmith, Rocky, Chris Grulke, R. Brooks, T. Transue, C. Tan, A. Frame, P. Egeghy, R. Edwards, D. Chang, R. Tornero-Velez, K. Isaacs, A. Wang, J. Johnson, K. Holm, M. Reich, J. Mitchell, D. Vallero, L. Phillips, M. Phillips, J. Wambaugh, R. Judson, T. Buckley, AND C. Dary. Development of a Consumer Product Ingredient Database for Chemical ExposureScreening and Prioritization. FOOD AND CHEMICAL TOXICOLOGY. Elsevier Science Ltd, New York, NY, 65:269-279, (2014).
Goldsmith, M., C. Grulke, D. Chang, T. Transue, S. Little, J. Rabinowitz, AND R. Tornero-Velez. DockScreen: A database of in silico biomolecular interactions to support computational toxicology. Dataset Papers in Science. Hindawi Publishing Corporation, New York, NY, 2014:1-5, (2014).
Yin, Y., D. Chang, C. Grulke, C. Tan, M. Goldsmith, AND R. Tornero-Velez. Essential Set of Molecular Descriptors for ADME Prediction in Drug and Environmental Chemical Space. Research. Synatom Research, Lambertville, NJ, (1):996, (2014).
Goldsmith, M., D. Vallero, P. Egeghy, D. Chang, Chris Grulke, C. Tan, AND J. Wambaugh. Ex Priori: Exposure-based Prioritization across Chemical Space. Presented at ISES 2014, Cincinnati, OH, October 12 - 16, 2014.
Holm, K., Rocky Goldsmith, D. Chang, Chris Grulke, M. Phillips, C. Tan, AND R. Tornero-Velez. Identification and Prioritization of Chemical Mixtures from Environmental Residue Data. Presented at SOT Annual Meeting, Phoenix, AZ, March 23 - 27, 2014.
Chang, D., Chris Grulke, Y. Yin, R. Tornero-Velez, M. Pasquinelli, AND Rocky Goldsmith. Too many chemicals, too little time: Rapid in silico methods to characterize and predict ADME properties for chemical toxicity and exposure potential. Presented at 18th Annual Green Chemistry & Engineering Conference, Bethesda, MD, June 17 - 19, 2014.
2013
Tan, C., M. Phillips, J. Sobus, D. Chang, AND Rocky Goldsmith. Biomarkers - Key to Exposure Reconstruction. Chapter 14, Yearbook of Science & Technology 2014. McGraw-Hill Companies, New York, NY, , 38-41, (2013).
Kenneke, J., S. Marchitti, S. Rawat, D. Chang, Chris Grulke, Chris Mazur, AND Rocky Goldsmith. Chiral Pesticide Pharmacokinetics: A Range of Values. Presented at Society of Toxicology Meeting, San Antonio, TX, March 10 - 14, 2013.
Chang, D., Rocky Goldsmith, A. Fraile Rodriguez, Chris Grulke, P. Egeghy, AND J. Mitchell-Blackwood. Data-Mining and Informatics Approaches for Environmental Contaminants. Edition 1, Chapter 1, McGraw-Hill Handbook of Science & Technology. McGraw-Hill Companies, New York, NY, , 1-9, (2014).
Kenneke, J., S. Marchitti, S. Rawat, Chris Mazur, Q. Cheng, M. Goldsmith, D. Chang, AND C. Grulke. Impact of In Vitro System, Chemical Mistures, and Stereochemistry on the Intrinsic Clearance of 1,2,4-Triazole Fungicides in Human and Rat. Presented at The 19th International Symposium on Microsomes and Drug Oxidations and 12th European ISSX Meeting, Noordwijk aan Zee, NETHERLANDS, June 17 - 21, 2012.
Goldsmith, Rocky, Chris Grulke, D. Chang, C. Tan, R. Brooks, C. Dary, AND D. Vallero. Personal Chemical Exposure informatics. Chapter 1, McGraw-Hill Handbook of Science & Technology. McGraw-Hill Companies, New York, NY, , 1-9, (2014).
Goldsmith, Rocky, C. Tan, D. Chang, Chris Grulke, R. Tornero-Velez, D. Vallero, C. Dary, J. Johnson, P. Egeghy, J. Mitchell-Blackwood, K. Holm, M. Reich, R. Edwards, AND L. Phillips. Summary Report for Personal Chemical Exposure Informatics: Visualization and Exploratory Research in Simulations and Systems (PerCEIVERS). U.S. Environmental Protection Agency, Washington, DC, EPA/600/R/13/041 (NTIS PB2013-108926), 2013.
2012
TAN, YU-MEI, C. C. DARY, D. CHANG, E. M. ULRICH, J. M. VAN EMON, J. XUE, J. D. PLEIL, J. F. KENNEKE, J. SOBUS, L. S. SHELDON, M. K. MORGAN, M. GOLDSMITH, R. TORNERO-VELEZ, R. HIGHSMITH, R. C. FORTMANN, T. W. COLLETTE, AND V. G. ZARTARIAN. Biomonitoring - An Exposure Science Tool for Exposure and Risk Assessment. U.S. Environmental Protection Agency, Washington, DC, EPA/600/R-12/039 (NTIS PB2012-112321), 2012.
TAN, YU-MEI, R. CONOLLY, D. CHANG, R. TORNERO-VELEZ, M. GOLDSMITH, S. PETERSON, AND C. C. DARY. Computational Toxicology: Application in Environmental Chemicals. Chapter 2, Brad Reisfeld and Arthur N. Mayeno (ed.), Computational Toxicology: Volume 1, Methods in Molecular Biology. Springer Science + Business Media, New York, NY, 929:1-11, (2012).
Chang, D., Rocky Goldsmith, R. Tornero-Velez, C. Tan, Chris Grulke, E. Ulrich, A. Lindstrom, M. Pasquinelli, J. Rabinowitz, AND C. Dary. In Silico Strategies for Modeling Stereoselective Metabolism of Pyrethroids. Chapter 16, Parameters for Pesticide QSAR and PBPK Models for Human Risk Assessment. American Chemical Society, Washington, DC, 1099:245-269, (2012).
GOLDSMITH, M., S. PETERSON, D. CHANG, T. R. Transue, R. TORNERO-VELEZ, YU-MEI TAN, AND C. C. DARY. Informing Mechanistic Toxicology with Computational Molecular Models. Chapter 7, B Reisfeld, A Mayeno (ed.), Computational Toxicology - Volume I, Methods in Molecular Biology. Springer Science + Business Media, New York, NY, 929(2012):139-165, (2012).
Goldsmith, Rocky, J. Johnson, D. Chang, R. Tornero-Velez, J. Knaak, AND C. Dary. Parameters for Pesticide QSAR and PBPK/PD Models to inform Human Risk Assessments. Chapter 1, James B. Knaak, Charles Timchalk, Rogelio Tornero-Velez (ed.), Parameters for Pesticide QSAR and PBPK/PD Models for Human Risk Assessment. American Chemical Society, Washington, DC, 1099:1-15, (2012).
KNAAK, J. B., C. C. DARY, X. Zhang, R. W. Gerlach, R. TORNERO-VELEZ, D. CHANG, M. GOLDSMITH, AND J. N. BLANCATO. Parameters for Pyrethroid Insecticide QSAR and PBPK/PD Models for Human Risk Assessment . Chapter INT, Springer, New York, NY, 219:1-114, (2012).
TAN, YU-MEI, J. SOBUS, D. CHANG, M. GOLDSMITH, R. TORNERO-VELEZ, J. D. PLEIL, AND C. C. DARY. Reconstructing Human Exposures Using Biomarkers and other "Clues". JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH - PART B: CRITICAL REVIEWS. Taylor & Francis, Inc., Philadelphia, PA, 15(1):15-38, (2012).
2010
GOLDSMITH, M., T. R. Transue, D. CHANG, R. TORNERO-VELEZ, AND C. C. DARY. PAVA: Physiological and Anatomical Visual Analytics for Mapping of Tissue-Specific Concentration and Time-Course Data. JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS. Springer, New York, NY, 37(3):277-287, (2010).
2009
TAN, C., E. J. WEBER, J. F. KENNEKE, M. K. MORGAN, D. CHANG, M. GOLDSMITH, R. TORNERO-VELEZ, AND C. C. DARY. Computational Approaches and Tools for Exposure Prioritization and Biomonitoring Data Interpretation. Presented at Computational Toxicology Board of Scientific Counselors Review, RTP, NC, September 29 - 30, 2009.
2006
CHANG, D., T. L. WHITEHEAD, M. S. OKINO, C. S. MAZUR, J. F. KENNEKE, R. TORNERO-VELEZ, J. C. JOHNSON, AND C. C. DARY. AN IN SILICO INVESTIGATION OF THE ENANTIOSELECTIVE METABOLISM RATES OF TRIAZOLE FUGICIDES. Presented at 14th North American International Society for the Study of Xenobiotics Meeting, Rio Grande, PUERTO RICO, October 22 - 26, 2006.
CHANG, D., M. S. OKINO, FRED W. POWER, R. TORNERO-VELEZ, J. F. KENNEKE, CHRIS S. MAZUR, C. C. DARY, AND TIM W. COLLETTE. ESTIMATION OF CHEMICAL SPECIFIC PARAMETERS WITHIN PHYSIOLOGICALLY BASED PHARMACOKINETIC/PHARMACODYNAMIC MODELS. Presented at EPA Science Forum 2006, Washington, DC, May 16 - 18, 2006.
CHANG, D., P. P. EGEGHY, J. B. KNAAK, R. TORNERO-VELEZ, M. S. OKINO, F. W. POWER, M. DELLARCO, C. S. MAZUR, J. F. KENNEKE, AND C. C. DARY. INFLUENCE OF MATRIX FORMULATION ON DERMAL PERCUTANEOUS ABSORPTION OF TRIAZOLE FUNGICIDES USING QSAR AND PBPK / PD MODELS. Presented at ISEA/ISEE 2006 , Paris, FRANCE, September 02 - 06, 2006.
2005
KNAAK, J. B., D. CHANG, C. C. DARY, R. TORNERO-VELEZ, M. S. OKINO, AND FRED W. POWER. ESTIMATION OF ADIPOSE TISSUE; BLOOD PARTITION COEFFICIENTS OF CARBAMATES AND ORGANOPHOSPHORUS PESTICIDES USING RELATIVE LIPID CONTENT AND LOGP AS THE MECHANISTIC DETERMINANTS. Presented at American Chemical Society Meeting and Exposition, Washington, DC, August 27 - September 01, 2005.