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RECORD NUMBER: 18 OF 22

OLS Field Name OLS Field Data
Main Title Simian Gastropathy with Submucosal Glands and Cysts, Gastritis Glandularis or Cystica Profunds.
Author Scotti., Thomas M. ;
CORP Author National Environmental Research Center, Cincinnati, Ohio.
Year Published 1973
Stock Number PB-280 841
Additional Subjects Stomach ; Monkeys ; Pesticides ; Toxicology ; Rhesus monkeys ; Diseases ; Glands(Anatomy) ; Pathology ; DDT ; Cysts ; Occurence ; Pathology ; Histology ; Chlorine organic compounds ; Toxic substances ; Reprints ; Gastropathy ; Squirrel monkeys ; Saimiri sciureus ; Parathion ; Lindane ; Aroclor 1260 ; Biphenyl/hexachloro ; Aroclor 1248
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NTIS  PB-280 841 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 6p
Abstract An unusual gastropathy with submucosal glands and cysts, usually associated with muncus-secreting cell hyperplasia of the mucosa, was observed at autopsy in 11 (52%) of 21 rhesus monkeys (Macaca mulatta), but in none of nine squirrel monkeys (Saimiri sciureus). In most instances, the gastric lesion occurred spontaneously, in contrast to similar lesions in monkeys of the genus Macaca reported by other investigators, which usually were attributed to known exposure to irritants. Evidence in this dtudy and in the literature suggests that the gastric mucosa of the rhesus monkey is highly reactive to nonspecific irritants. The simian gastropathy sometimes resembles an infrequently observed gastric lesion in man, reported as diffuse heterotopic cystic malformation, and is analogous to the intestinal entity, also occuring in man, known as colitis cystica profunda.
Supplementary Notes Pub. in Archives of Pathology, v96 p403-408, Dec 73.
Availability Notes Included in the report, Journal Articles on Toxicology. Group 16, PB-280 830.
Title Annotations Reprint: Simian Gastropathy with Submucosal Glands and Cysts, Gastritis Glandularis or Cystica Profunds,
PUB Date Free Form 25 Jun 73
Category Codes 6E; 6T; 57O; 57Y; 68E
NTIS Prices (Order as PB-280 830, MF A01)
Primary Description 500/01
Document Type NT
Cataloging Source NTIS/MT
Control Number 323740989
Origin NTIS
Type CAT