| Main Title |
Twenty-eight Day Subchronic Dermal Toxicity Study in Rats on API-HNC-1 (High Nitrogen Crude Petroleum Oil); API-SFP-105 (No. 1 Hydrotreated Shale Oil to 0.19% Nitrogen Level); API-SFP-206 (No. 2 Hydrotreated Shale Oil to 0.06% Nitrogen Level); API-SFR-1 (Raw Shale Oil No. 1) and API-SFR-2 (Raw Shale Oil No. 2). Final Report from Springborn Institute for Bioresearch, Inc. |
| CORP Author |
American Petroleum Inst., Washington, DC.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Publisher |
5 Sep 1985 |
| Year Published |
1985 |
| Report Number |
FYI-AX-0285-0381; |
| Stock Number |
OTS-0000381-1 |
| Additional Subjects |
Toxicity ;
Rats ;
Skin(Anatomy) ;
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS-0000381-1 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
337p |
| Abstract |
The potential toxocities due to dermal exposure to six shale-derived hydrocarbon mixtures were evaluated using rats. Animals were dosed five days per week for four weeks. The application site was occluded six hours after dosing. Dose levels for each test article were 0.25 g/kg and 2.5 g/kg. The control group was sham treated. Body weights, food consumption, overt toxicity, and dermal responses were recorded. Blood was obtained at the end of the study and used for hematology and clinical chemistry evaluations. A selection of approximately twenty different organs or tissues from the control and high-dose animals plus all lesions was evaluated microscopically. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with American Petroleum Inst., Washington, DC. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| Category Codes |
57Y |
| NTIS Prices |
PC A16/MF A03 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
010001280 |
| Origin |
NTIS |
| Type |
CAT |
