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RECORD NUMBER: 231 OF 2777Main Title | Aromatic Amines: An Assessment of the Biological and Environmental Effects. | |||||||||||
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CORP Author | National Research Council, Washington, DC.;Environmental Protection Agency, Washington, DC. | |||||||||||
Year Published | 1981 | |||||||||||
Report Number | EPA-68-01-4655; | |||||||||||
Stock Number | PB83-133058 | |||||||||||
Additional Subjects | Amines ; Aromatic hydrocarbons ; Environmental surveys ; Toxicology ; Assessments ; Exposure ; Aniline ; Pesticides ; Metabolism ; Carcinogens ; Risk ; Epidemiology ; Occurrence ; Physiological effects ; Toxic substances ; Biological effects ; Furazolidone ; Aniline/chloro ; Toluene/diamino ; Trifluralin ; Anisidine/methyl | |||||||||||
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Collation | 327p | |||||||||||
Abstract | Aromatic amines and compounds related through metabolism are used widely in industry. As a result of such applications, they are also dispersed into the environment, thereby creating a potential for human exposure. Four aromatic are known to lead to urinary tract cancer in exposed humans, and some are also responsible for the induction of methemoglobinemia. Some other structurally similar amines are carcinogenic to one or more tissues in laboratory animals. This report summarizes the key information concerning the occurrence, analysis, and toxicology of the aromatic amines and then considers six specific amines in detail. The following substances were studied: Aniline, 4,4'Methylene-Bis (2Chloraniline), 2,4-Diaminotoluene, trifluralin, p-Cresidine, and furazolidone. The following topics are covered: occurrence in the environment, general analysis, metabolism, carcinogenc potency and risk estimation, and epidemiology. | |||||||||||
NTIS Title Notes | Final rept. | |||||||||||
PUB Date Free Form | 1981 | |||||||||||
Category Codes | 6T; 6E; 68#; 57Y#; 57O | |||||||||||
NTIS Prices | PC A15/MF A01 | |||||||||||
Primary Description | 100/00 | |||||||||||
Document Type | NT | |||||||||||
Cataloging Source | NTIS/MT | |||||||||||
Control Number | 306323289 | |||||||||||
Origin | NTIS | |||||||||||
Type | CAT |