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OLS Field Name OLS Field Data
Main Title Causes of papillomas on fish exposed to chlorinated sewage effluent
Author Grizzle, John M. ; Melius, P.
Other Authors
Author Title of a Work
Melius, Paul.
CORP Author Auburn Univ., AL.;Environmental Research Lab., Gulf Breeze, FL.
Publisher U.S. Environmental Protection Agency, Environmental Research Laboratory ;
Year Published 1984
Report Number EPA-600/3-84-076; EPA-R-809336; PB84223023
Stock Number PB84-223023
OCLC Number 48237155
Subjects Mutagenicity testing ; Fish populations--Alabama ; Fishes--Effect of water pollution on ; Sewage--Chlorination
Additional Subjects Papilloma virus ; Fishes ; Chlorination ; Sewage treatment ; Toxicity ; Exposure ; Carcinogens ; Organic compounds ; Mutagens ; Neoplasms ; Ictalurus melas
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
ELDD  EPA-600/3-84-076 CCTE/GLTED Library/Duluth,MN 01/25/2002
NTIS  PB84-223023 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 01/01/1988
Collation viii, 22 p.
Abstract This research was initiated to determine the cause of oral papillomas in black bullheads (Ictalurus melas) from the final oxidation pond of the Tuskegee, Alabama, sewage treatment plant. The water in this pond was chlorinated effluent from the sewage treatment plant. The presence of a carcinogenic and mutagenic chemical in the effluent of a sewage treatment plant was indicated by papillomas developing on caged black bullheads, glucuronosyltransferase induction in caged channel catfish, and Ames-test mutagenicity of water extract. Unlike previously studied fish papillomas, virus-like particles were not present in the tumor cells. Although mutagenic and carcinogenic chemicals have not been identified in the wastewater, chlorine is implicated as a factor contributing to the induction of the papillomas because the prevalence of papillomas on wild black bullheads exposed to the effluent decreased from 73% to 23% after the chlorination rate was reduced.
Notes "PB84-223023" "July 1984" Includes bibliographical references.
Place Published Gulf Breeze, FL :
Corporate Au Added Ent Environmental Research Laboratory (Gulf Breeze, Fla.)
PUB Date Free Form 1983.
NTIS Prices PC A03/MF A01
BIB Level m
Cataloging Source OCLC/T
OCLC Time Stamp 20020115113608
Language eng
Origin OCLC
OCLC Rec Leader 01015nam 2200277Ka 45020