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RECORD NUMBER: 161 OF 1229

OLS Field Name OLS Field Data
Main Title Cytogenetic Distinction between the TK+ and TK- Chromosomes in the L5178Y TK+/- 3.7.2C Mouse-Lymphoma Cell Line.
Author Hozier, J. ; Sawyer, J. ; Clive, D. ; Moore, M. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. ;Florida Inst. of Tech., Melbourne.;Burroughs Wellcome Co., Research Triangle Park, NC.
Year Published 1982
Report Number EPA/600/J-82/462;
Stock Number PB86-202975
Additional Subjects Chromosomes ; Lymphoma ; Mice ; Mutants ; Reprints ; Cell lines ; Cytogenesis ; Mutagenesis
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NTIS  PB86-202975 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/21/1988
Collation 7p
Abstract The authors have analyzed the banded metaphase karyotypes of the L5178Y TK+/-3.72C mouse-lymphoma cell line as well as a class of slow growing (o) TK-/-mutants which show chromosome 11 rearrangements. The authors have discovered a centromeric heteromorphism in the chromosomes 11 (the known location of the thymidine kinase gene in the mouse) which, together with the types of chromosome rearrangements thus far catalogued for TK+/- TK-/- mutagenesis, allows us to propose a cytogenetic distinction between the TK-competent (TK+) and TK-deficient (TK-) chromosome.
Supplementary Notes Pub. in Mutation Research 105, n6 p451-456 Dec 82. Prepared in cooperation with Florida Inst. of Tech., Melbourne. Sponsored by Burroughs Wellcome Co., Research Triangle Park, NC.
NTIS Title Notes Journal article.
Title Annotations Reprint: Cytogenetic Distinction between the TK+ and TK- Chromosomes in the L5178Y TK+/- 3.7.2C Mouse-Lymphoma Cell Line.
PUB Date Free Form c1982
Category Codes 6C; 57F
NTIS Prices PC A02/MF A01
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 621323628
Origin NTIS
Type CAT