Main Title |
Chemically Induced Aneuploidy in Mammalian Cells in Culture. |
Author |
Galloway, S. M. ;
Ivett, J. L. ;
|
CORP Author |
Oak Ridge National Lab., TN. ;Merck Inst. for Therapeutic Research, West Point, PA. ;Litton Bionetics, Inc., Kensington, MD.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment. |
Year Published |
1986 |
Report Number |
EPA-68-02-3839; EPA/600/J-86/080; |
Stock Number |
PB86-205630 |
Additional Subjects |
Toxicology ;
Cell cultures ;
Mammals ;
Reprints ;
Aneuploidy
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB86-205630 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
20p |
Abstract |
A committee of scientists was established by the U.S. Environmental Protection Agency to appraise the current state of aneuploidy test methodology, to compile and analyze published data on the chemical induction of aneuploidy, and to provide guidance for additional test development and validation. The committee was organized into 9 working groups, representing different eukaryotic organisms ranging from fungi to whole mammals. The Environmental Mutagen, Carcinogen, and Teratogen Information Program at Oak Ridge National Laboratory identified and provided literature to the working groups. The 9 reports were prepared by the individual working groups. The reports include: (1) descriptions of the available testing approaches and general principles to be followed for protocol development, (2) criteria for evaluating data, and (3) recommendations for future test development and basic research. The evaluated results are presented in tables. |
Supplementary Notes |
Pub. in Mutation Research 167, p89-105 Jan 86. Prepared in cooperation with Merck Inst. for Therapeutic Research, West Point, PA., and Litton Bionetics, Inc., Kensington, MD. Sponsored by Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Chemically Induced Aneuploidy in Mammalian Cells in Culture. |
PUB Date Free Form |
c1986 |
Category Codes |
6T; 57Y; 57F |
NTIS Prices |
PC A02/MF A01 |
Primary Description |
600/21 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
622717327 |
Origin |
NTIS |
Type |
CAT |