Main Title |
Comparison Methods for the Determination of Alkyl Phosphates in Urine. |
CORP Author |
Environmental Protection Agency, Washington, DC. Office of Research and Development. |
Publisher |
Sep 2003 |
Year Published |
2003 |
Report Number |
EPA/600/R-03/075; |
Stock Number |
PB2004-103372 |
Additional Subjects |
Toxicology ;
Pesticides ;
Urinalysis ;
Laboratories ;
Handling ;
Urine ;
Organophosphate pesticides ;
Analytical methods ;
Interlaboratory comparisons ;
Human exposure pathways ;
Metabolites ;
Comparisons ;
Concentration ;
Accuracy ;
Statistics ;
Alkyl phosphates
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB2004-103372 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
70p |
Abstract |
Organophosphorous (OP) pesticides have been used heavily in the United States and have been detected in dust, handwipes, drinking water, food, and air indicating human exposure pathways. Inside the body, these pesticides are metabolized mostly to one of six alkyl phosphate compounds: dimethylphosphate, dimethylphosphorodithioate, dimethylphosphorothioate, diethylphosphate, diethylphosphorothioate, and diethylphosphorodithioate. These metabolites have been detected in urine and the quantity of these metabolites in urine has been shown to correlate with the pesticide dose that a person has experienced. Therefore, the measurement of these urinary metabolites can be used to evaluate exposure. Unfortunately, this measurement is not straightforward. To characterize the performance of four existing analytical methods used to analyze urine samples for the six urinary alkyl phosphate metabolites of OP pesticides, an interlaboratory comparison study was done. |
Availability Notes |
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Category Codes |
57Y; 44H; 95C; 99A |
NTIS Prices |
PC A05/MF A01 |
Primary Description |
600/00 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
020000130 |
Origin |
NTIS |
Type |
CAT |