Main Title |
Detection of Occupational Exposure to Genotoxic Agents with a Urinary Mutagen Assay. |
Author |
Kriebel, D. ;
Commoner, B. ;
Bollinger, D. ;
Bronsdon, A. ;
Gold, J. ;
|
CORP Author |
Queens Coll., Flushing, NY. Center for the Biology of Natural Systems.;Health Effects Research Lab., Research Triangle Park, NC. |
Year Published |
1983 |
Report Number |
EPA-R-804395; EPA/600/J-83/352; |
Stock Number |
PB86-231826 |
Additional Subjects |
Industrial medicine ;
Smoking ;
Detection ;
Exposure ;
Reprints ;
Urinalysis ;
Genotoxic agents ;
Ames test
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB86-231826 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
14p |
Abstract |
The levels of mutagenic activity in the urine of 198 smoking and non-smoking chemical workers, coke plant workers and controls were measured using a urinary mutagen assay based on the Ames Salmonella/microsome test. Urine samples were concentrated using the non-polar resin XAD-2 eluted with methylene chloride and acetone. Activity towards Salmonella strains TA1538 and TA100 with and without microsomal preparation S-9 was measured. Regardless of occupational exposure, smokers had considerably higher urinary mutagenic activity than non-smokers on Strain TA1538 with S-9, and to a lesser extent on Strain TA100 with S-9. |
Supplementary Notes |
Pub. in Mutation Research, v108 n1 p67-79 Mar 83. Sponsored by Health Effects Research Lab., Research Triangle Park, NC. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Detection of Occupational Exposure to Genotoxic Agents with a Urinary Mutagen Assay. |
PUB Date Free Form |
c1983 |
Category Codes |
6J; 57U; 68G |
NTIS Prices |
PC A02/MF A01 |
Primary Description |
600/11 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
628226435 |
Origin |
NTIS |
Type |
CAT |