Main Title |
Biochemical Changes in Humans Upon Exposure to Nitrogen Dioxide While at Rest. |
Author |
Chaney, Suzanne ;
Blomquist, Wendy ;
DeWitt, Paulett ;
Muller, Keith ;
|
CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. |
Year Published |
1981 |
Report Number |
EPA-600/J-80-108; |
Stock Number |
PB82-127473 |
Additional Subjects |
Nitrogen dioxide ;
Humans ;
Exposure ;
Physiological effects ;
Responses ;
Air pollution ;
Reprints ;
Air pollution effects(Humans)
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB82-127473 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
7p |
Abstract |
The biochemical response to controlled exposures of nitrogen dioxide (NO2) was studied in 19 human subjects exposed to 0.2 ppm NO2 for 2 hr and compared to 15 control subjects exposed to filtered air for 2 hr. Seven biochemical blood parameters, including glutathione, red blood cell glutathione reductase, 2,3-diphosphoglycerate, methemoglobin, vitamine E, complement C3, and IgA were measured prior to exposure, immediately after exposure, and 22 hr following exposure. The only variable that showed significant change due to NO2 exposure was glutathione. Glutathione is known to protect the erythrocyte from oxidative stress. The increase in glutathione observed upon exposure to NO2 may be a protective reaction of the erythrocyte to meet the oxidative stress. |
Supplementary Notes |
Pub. in Archives of Environmental Health, v36 n2 p53-58 1981. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Biochemical Changes in Humans Upon Exposure to Nitrogen Dioxide While at Rest. |
PUB Date Free Form |
Sep 81 |
Category Codes |
6F; 68A |
NTIS Prices |
PC A02/MF A01 |
Primary Description |
600/11 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
323807706 |
Origin |
NTIS |
Type |
CAT |