Main Title |
Updated mutagenicity and carcinogenicity assessment of cadmium. |
CORP Author |
United States. Environmental Protection Agency. Office of Health and Environmental Assessment.; Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment. |
Publisher |
U.S. Environmental Protection Agency, Office of Research and Development, Office of Health and Environmental Assessment, |
Year Published |
1985 |
Report Number |
EPA-600/8-83-025F |
Stock Number |
PB85-243533 |
OCLC Number |
12959913 |
Subjects |
Cadmium--Toxicology ;
Environmental health ;
Carcinogens
|
Additional Subjects |
Cadmium--Toxicology ;
Environmental health ;
Carcinogens ;
Toxicology ;
Assessments ;
Public health ;
Risk ;
Exposure ;
Metals ;
Smoking ;
Food ;
Concentrations(Compositions) ;
Physiological effects ;
Heavy metals ;
Cigarette smoking ;
Bioaccumulation ;
Toxic substances ;
Health risks
|
Internet Access |
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
EHAM |
RA1231 .C3U6 1983 |
|
Region 1 Library/Boston,MA |
04/29/2016 |
EJED |
EPA 600/8-83-025F |
|
OCSPP Chemical Library/Washington,DC |
01/01/1988 |
EKBD |
EPA-600/8-83-025f |
|
Research Triangle Park Library/RTP, NC |
04/11/1997 |
ELBD ARCHIVE |
EPA 600-8-83-025F |
Received from HQ |
AWBERC Library/Cincinnati,OH |
10/04/2023 |
DISPERSAL |
ERAD |
EPA 600/8-83-025F |
|
Region 9 Library/San Francisco,CA |
02/19/2013 |
ESAD |
EPA 600-8-83-025F |
|
Region 10 Library/Seattle,WA |
03/23/2010 |
NTIS |
PB85-243533 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
x, 192 pages : illustrations ; 28 cm |
Abstract |
The document evaluates the mutagenicity and carcinogenicity of cadmium, supplementing an earlier document (Health Assessment Document for Cadmium, May 1981) which dealt with all health effects. Since the earlier document was prepared, a rat inhalation carcinogenicity study has been reported and several epidemiology and mutagenicity papers have been published. This document concludes that: (1) there is mixed evidence on the mutagenicity of various cadmium salts; (2) cadmium chloride aerosol induces lung cancer in rats; (3) injected cadmium salts induce injection site sarcomas and testicular tumors in both mice and rats; (4) there is limited epidemiologic evidence that inhaled cadmium is dose-related to lung cancer in exposed workers; (5) there is no evidence that cadmium is carcinogenic via ingestion, which is a major route of human exposure, and the upper limit of potency via ingestion is at least 100 times less than via inhalation. |
Notes |
"EPA-600/8-83-025F." "June 1985." "Final." "Addendum to the Health Assessment Document for Cadmium (May 1981)--EPA-600/8-81-023." |
Contents Notes |
"This document evaluates the mutagenicity and carcinogen!city of cadmium, supplementing an earlier document (Health Assessment Document for Cadmium, May 1981) which dealt with all health effects. Since the earlier document was prepared, a rat inhalation carcinogenicity study has been reported and several epidemiology and mutagenicity papers have been published. This document concludes that: (1) there is mixed evidence on the mutagenicity of various cadmium salts; (2) cadmium chloride aerosol induces lung cancer in rats; (3) injected cadmium salts induce injection site sarcomas and testicular tumors in both mice and rats; (4) there is limited epidemiologic evidence that inhaled cadmium is dose-related to lung cancer in exposed workers; (5) there is no evidence that cadmium is carcinogenic via ingestion, which is a major route of human exposure, and the upper limit of potency via ingestion is at least 100 times less than via inhalation."--Abstract |
Place Published |
Washington, D.C. |
Supplementary Notes |
See also PB82-115163. |
Corporate Au Added Ent |
United States. Environmental Protection Agency. Office of Health and Environmental Assessment. |
PUB Date Free Form |
1985 |
NTIS Prices |
PC A10/MF A01 |
BIB Level |
m |
Document Type |
BC |
Medium |
unmediated |
Content |
text |
Carrier |
volume |
Cataloging Source |
OCLC/T |
OCLC Time Stamp |
20160419144057 |
Language |
eng |
Origin |
OCLC |
Type |
MERGE |
OCLC Rec Leader |
01447cam 2200361Ia 45020 |