Main Title |
Comparative Toxicity of Azinphos-Methyl to House Mice, Laboratory Mice, Deer Mice, and Gray-Tailed Voles. |
Author |
Meyers, S. M. ;
Wolff, J. O. ;
|
CORP Author |
ManTech Environmental Technology, Inc., Corvallis, OR. ;Oregon State Univ., Corvallis. Dept. of Fisheries and Wildlife.;Corvallis Environmental Research Lab., OR. |
Publisher |
c1994 |
Year Published |
1994 |
Report Number |
EPA-68-C8-0006; EPA/600/J-94/272; |
Stock Number |
PB94-182367 |
Additional Subjects |
Toxicity ;
Pesticides ;
Insecticides ;
Risk assessment ;
Mice ;
Dosage ;
Mortality ;
Body weight ;
Field tests ;
Oral administration ;
Acute exposure ;
Lethal doses ;
Cholinesterase ;
Reprints ;
Azinphos-methyl ;
Guthion ;
Mus musculus ;
Microtus canicaudus ;
Peromyscus maniculatus ;
Voles
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB94-182367 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
7p |
Abstract |
The authors conducted a laboratory toxicity study on house mice and laboratory mice, gray-tailed voles, and deer mice as part of a comprehensive laboratory and field study to field-validate laboratory-based risk assessment of argichemicals. The single dose oral LD50 for the organophosphorus insecticide azinphos-methyl was 10, 11, 32, 48 mg/kg body mass in wild house mice, laboratory mice, gray-tailed voles, and deer mice, respectively. The authors conclude that (1) laboratory mice were not representative of deer mice or gray-tailed voles with respect to sensitivity to the pesticide, but provided a conservative estimates for risk assessment; (2) 5-d dietary LC50 tests provide substantially higher estimates of toxicity to rodents than do 10-d test; and (3) ChE depression of 45 to 50% was lethal. |
Supplementary Notes |
Pub. in Archives of Environmental Contamination and Toxicology, v26 p478-482 1994. Prepared in cooperation with Oregon State Univ., Corvallis. Dept. of Fisheries and Wildlife. Sponsored by Corvallis Environmental Research Lab., OR. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Comparative Toxicity of Azinphos-Methyl to House Mice, Laboratory Mice, Deer Mice, and Gray-Tailed Voles. |
Category Codes |
57Y; 68E |
NTIS Prices |
PC A02/MF A01 |
Primary Description |
600/02 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
421724833 |
Origin |
NTIS |
Type |
CAT |