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RECORD NUMBER: 58 OF 184

Main Title Initial Submission: Dermal Sensitization of Santoflex Compounds in Humans with Cover Letter dated 08/07/1992.
CORP Author Industrial and Biomedical Sensors Corp., Waltham, MA.; Monsanto Chemical Co., St. Louis, MO.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1992
Report Number 8EHQ-0892-10277
Stock Number OTS0570859
Additional Subjects Toxicology ; Health effects ; Toxic substances ; Santoflex compounds ; Primary dermal sensitization ; Mammals ; Humans ; Dermal ; CAS No 793-24-8 ; CAS No 3081-01-4 ; CAS No 3081-14-9
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NTIS  OTS0570859 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 29p
Abstract Patch tests were conducted on fifty human subjects using the Shelanski method (Proceedings of the Toilet Goods Association, No. 19, May 1953) as modified. A square of the test material was applied to the arm of each test subject and held in place with adhesive tape. After 24 hours the patch was removed and the site examined for reactions after which the material was reapplied. Reap- plications were normally made to the same site unless a 2+ or greater reaction occurred. In this event a new site was chosen. Fifteen such primary applica- tions were made except in those cases where it was deemed clinically advisable to terminate the applications earlier. Following the primary applications a two week rest was permitted after which a challenge application was applied as before.
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PUB Date Free Form 27 Aug 1992
Category Codes 57Y; 57U; 68G; 99; 44G
NTIS Prices PC A03/MF A03
Document Type NT
Cataloging Source NTIS/MT
Control Number 018800230
Origin NTIS
Type CAT