Main Title |
Identification of aneuploidy-inducing agents using the wheat seedling assay / |
Author |
Sandhu, S. S. ;
Dhesi, J. S. ;
Gill, B. S.
|
CORP Author |
Environmental Health Research and Testing, Inc., Research Triangle Park, NC. ;North Carolina Central Univ., Durham.;Health Effects Research Lab., Research Triangle Park, NC. Genetic Toxicology Div. |
Publisher |
U.S. Environmental Protection Agency, Office of Research and Development, Health Effects Research Laboratory, |
Year Published |
1989 |
Report Number |
EPA/600/D-89/091; EPA-68-02-4456 |
Stock Number |
PB89-223978 |
Additional Subjects |
Toxicity ;
Mutagens ;
Wheat plants ;
Cyclophosphamide ;
Chromium inorganic compounds ;
Aneuploidy ;
Mutagenicity tests ;
Chromosome aberrations ;
Alleles ;
DNA repair
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB89-223978 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
17 pages ; 28 cm |
Abstract |
A short-term assay using Chinese spring wheat for detecting induced aneuploidy and/or clastogenicity is described. The seed of virescent wheat (v1v1) are treated with a test agent. The appearance of white sectors (v1v1v1) or green sectors (v10) on the virescent leaves indicates the gain or loss of a chromosome or a segment of a chromosome bearing v1 allele. Three test chemicals, chromium trioxide (100-5,000 microg/ml), chromium dichromate (500-5,000 microg/ml), and cyclophosphamide (100-1,000 microg/ml) produced a dose-related positive response for chromosome aberrations in the assay. |
Notes |
EPA/600/D-89/091. PB89-223978. Microfiche. |
Place Published |
Research Triangle Park, NC : |
Supplementary Notes |
Prepared in cooperation with North Carolina Central Univ., Durham. Sponsored by Health Effects Research Lab., Research Triangle Park, NC. Genetic Toxicology Div. |
Corporate Au Added Ent |
Dhesi, J. S. ; Gill, B. S. ; United States. Environmental Protection Agency. Office of Research and Development. ; Health Effects Research Laboratory. |
PUB Date Free Form |
1989. |
NTIS Prices |
PC A03/MF A01 |
BIB Level |
m |
Cataloging Source |
OCLC/T |
OCLC Time Stamp |
20000914183127 |
Language |
eng |
Origin |
NTIS |
Type |
MERGE |
OCLC Rec Leader |
01133nam 2200277Ka 45020 |