Full Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Metabolomics A Powerful Tool in Systems Biology / [electronic resource] :
Author Nielsen, Jens.
Other Authors
Author Title of a Work
Jewett, Michael C.
Publisher Springer Berlin Heidelberg : Imprint: Springer,
Year Published 2007
Call Number QD415-436
ISBN 9783540747192
Subjects Life sciences. ; Biochemistry. ; Bioinformatics. ; Biology--Data processing. ; Microbial genetics. ; Cytology--Research_xMethodology.
Internet Access
Description Access URL
Collation online resource.
Notes Due to license restrictions, this resource is available to EPA employees and authorized contractors only
Contents Notes The role of metabolomics in systems biology -- Analytical methods from the perspective of method standardization -- Reporting standards -- The Golm Metabolome Database: a database for GC-MS based metabolite profiling -- Reconstruction of dynamic network models from metabolite measurements -- Toward metabolome-based 13C flux analysis: a universal tool for measuring in vivo metabolic activity -- Data acquisition, analysis, and mining: Integrative tools for discerning metabolic function in Saccharomyces cerevisiae -- E. coli metabolomics: capturing the complexity of a "simple" model -- The exo-metabolome in filamentous fungi -- The importance of anatomy and physiology in plant metabolomics. The metabolome comprises the complete set of metabolites, the non-genetically encoded substrates, intermediates, and products of metabolic pathways, associated to a cell. Given the increasing demand to quantitatively identify the metabolome and understand how trafficking of metabolites through the metabolic network impact cellular behavior, metabolomics has emerged as an important complementary technology to the cell-wide measurements of mRNA, proteins, fluxes, and interactions (e.g. protein-DNA). Metabolomics is already a powerful tool in drug discovery and development and in metabolic engineering. While maintaining these strengths, the field promises to play a heightened role in systems biology research, which is transforming the practice of medicine and our ability to engineer living organisms. This book brings together the latest results in the field of metabolomics. It comprehensively presents the current state of the metabolomics field by underscoring experimental methods, analysis techniques, standardization practices, and advances in specific model systems. As a result, it significantly broadens our perspective on the principles and strategies underpinning this emerging field.
Place Published Berlin, Heidelberg
Corporate Au Added Ent SpringerLink (Online service)
Title Ser Add Ent Topics in Current Genetics, 18
Host Item Entry Springer eBooks
PUB Date Free Form 2007
Series Title Untraced Topics in Current Genetics, 18
BIB Level m
Medium computer
Content text
Carrier online resource
Cataloging Source OCLC/T
OCLC Time Stamp 20131218223936
Language eng
OCLC Rec Leader 03717nam a22005415i 45