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Main Title Visual Effects Accompanying TEPP-Induced Miosis.
Author Upholt, William M. ; Quinby, Griffith E. ; Batchelor, Gordon S. ; Thompson., James P. ;
CORP Author Environmental Protection Agency, Chamblee, Ga. Chamblee Toxicology Lab.
Year Published 1956
Stock Number PB-279 187
Additional Subjects Pesticides ; Visual perception ; Toxicology ; Industrial medicine ; Dust ; Humans ; Eye(Anatomy) ; Experimental data ; Pilots(Personnel) ; Physiological effects ; Dosage ; Pyrophosphoric acid/tetraethyl ; Reprints ; Meiosis ; Toxic substances ; Occupational safety and health
Library Call Number Additional Info Location Last
NTIS  PB-279 187 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 7p
Abstract Pilots and others have long recognized the miosis which is frequently a consequence of applying tetraethylpyrophosphate (TEPP) dust by aircraft. Accompanying the miosis, operating pilots have regularly noted a decrease in light perception and have more rarely experienced an inability to judge distance. Two drops of 0.05% TEPP instilled into each eye of volunteers produced slight miosis and a slight increase of near accommodation. Two drops of 0.1% TEPP instilled into each eye of volunteers produced maximal miosis, an increase in near and far accommodation, and a decrease in light perception but no inability to judge distance. Two drops of 0.1% TEPP in only one eye of each of seven volunteers produced unilateral miosis and other expected changes in the treated eye but also caused all the volunteers to complain of difficulty in vision; four of the volunteers complained specifically of difficulty in judging distance, and six of them made sensorimotor errors of fumbling, stumbling, or other clumsiness.
Supplementary Notes Pub. in the A. M. A. Archives of Ophthalmology, v56 p128-134, Jul 56.
Availability Notes Included in the report, Journal Articles on Toxicology. Group 5, PB-279 175.
Title Annotations Reprint: Visual Effects Accompanying TEPP-Induced Miosis,
PUB Date Free Form 28 Mar 56
Category Codes 6T; 6J; 57Y; 57U; 68G; 68E
NTIS Prices (Order as PB-279 175, MF A01)
Primary Description 500/01
Document Type NT
Cataloging Source NTIS/MT
Control Number 323737872
Origin NTIS
Type CAT