Main Title |
Soluble Lung Protein in Experimental Silicosis and Berylliosis (Rastvorimye Belki Legkogo pri Eksperimentalnom Silikoze i Berillioze). |
Author |
Veretinskaya, A. G. ;
Kurysheva., N. G. ;
|
CORP Author |
Environmental Protection Agency, Research Triangle Park, N.C. Translation Services Section. |
Year Published |
1969 |
Report Number |
EPA-TR-76-104; |
Stock Number |
PB-254 496-T |
Additional Subjects |
Silicosis ;
Berylliosis ;
Proteins ;
Lung ;
Respiratory diseases ;
Pathology ;
Silicon ;
Beryllium ;
Chemical reactions ;
Experimental data ;
Laboratory animals ;
Rats ;
Translations ;
USSR ;
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB-254 496-T |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
6p |
Abstract |
A very important role in the pathogenesis of silicosis and berylliosis has been attributed to the interaction of silicone and beryllium with proteins. Since the above compounds reach the organism mainly through the respiratory pathways, it is natural to expect the greatest changes in the proteins of the lung. The objective has been to make a comparative study of the soluble lung proteins in experimental silicosis and berylliosis. Data on the contents of soluble lung protein in experimental silicosis and berylliosis show that the changes occur in opposite directions. While under conditions of experimental silicosis, a sharp decrease takes place in protein concentration when its total content in the tissue is almost unchanged, in berylliosis, on the contrary, an increase in total protein content is observed and a lack of change in protein concentration. With regard to the dry weight of lungs, it characteristically increases both in silicosis and in berylliosis. The increase in the weight of the lungs in rats with experimental berylliosis coincides in time with the marked increase in the total amount of soluble proteins. No such relationship was found in silicosis. |
Supplementary Notes |
Trans. of Gigiena Truda i Professionalnye Zabolevaniya (USSR) v13 n9 p46-47 1969. |
Title Annotations |
+++Soluble Lung Protein in Experimental Silicosis and Berylliosis (Rastvorimye Belki Legkogo pri Eksperimentalnom Silikoze i Berillioze)--Translation. |
PUB Date Free Form |
1969 |
Category Codes |
6A; 6E |
NTIS Prices |
PC A02/MF A01 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
326621017 |
Origin |
NTIS |
Type |
CAT |