| Main Title |
Letter from Chemical Manufacturers Assoc to Usepa Regarding Enclosed Materials Presented at 091086 Public Meeting with Chemical Manfacturers Assoc & Eastman Kodak Co W-attached. |
| CORP Author |
Chemical Manufacturers Association, Washington, DC.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
2000 |
| Report Number |
40-8699090 |
| Stock Number |
OTS0525397 |
| Additional Subjects |
Toxicology ;
Health effects ;
Triethylene Glycol Ethers ;
Pharmaco Kinetics ;
Mammals ;
Humans ;
In Vitro ;
Subchronic Toxicity ;
Rabbits ;
Dermal ;
Reproduction/fertility Effects ;
Teratogenicity ;
Rats ;
Oral ;
Gavage ;
Toxic substances ;
Laboratory animals ;
CAS No 109-86-4 ;
CAS No 110-80-5 ;
CAS No 111-76-2 ;
CAS No 111-77-3 ;
CAS No 111-90-0 ;
CAS No 112-34-5 ;
CAS No 112-35-6 ;
CAS No 112-50-5 ;
CAS No 143-22-6
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0525397 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
20p |
| Abstract |
Summary toxicokinetic and toxicity information regarding glycol ethers is presented. Comparitive absorption rates of glycol ethers through human epidermis in vitro ranged from 22.2 ug/sq cm/hr (for triethylene monobutyl ether) to 2705 ug/sq cm/hr (for ethylene monomethyl ether). In a dermal limit test with rabbits, each glycol ether was administered at 1 g/kg under occlusion to shaved backs of rabbits for 6 hrs/day, 5 days/week for 3 weeks. No toxic effects were noted other than irritation at the site of application. CMA briefly outlined a proposed subchronic dermal toxicity study of triethylene glycol methyl ether with rabbits. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
2000 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A03/MF A03 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
028802590 |
| Origin |
NTIS |
| Type |
CAT |
