| Main Title |
Application of the 'Tradescantia micronucleus' Assay for the Genetic Evaluation of Chemical Mixtures in Soil and Aqueous Media. |
| Author |
Gill, B. S. ;
Sandhu, S. S. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. ;Environmental Health Research and Testing, Inc., Research Triangle Park, NC. |
| Publisher |
c1992 |
| Year Published |
1992 |
| Report Number |
EPA/600/J-92/439; |
| Stock Number |
PB93-141380 |
| Additional Subjects |
Micronucleus tests ;
Mutagens ;
Soil contamination ;
Water pollution effects(Plants) ;
Arsenic oxides ;
Dieldrin ;
Reprints ;
Tradescantia ;
Lead tetraacetate
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB93-141380 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
7p |
| Abstract |
Genotoxic evaluation of nine binary and one tertiary mixtures of arsenic trioxide, dieldrin, and lead tetraacetate were performed using the Tradescantia micronucleus (Trad-MN) assay. The chemical mixtures were either (1) mixed into soil, and chemical exposure to the target cells was through the roots of intact plants grown in the soil or (2) through stem cuttings in which the inflorescences were treated with an aqueous solution of the test chemicals. Clastogenic responses were obtained for six out of the ten chemical mixtures, irrespective of the treatment conditions although relatively higher frequencies of MN were observed in plants exposed to the test chemicals in soil. The clastogenicity of the chemical mixtures was modified by the ratio of the individual chemical in a particular mixture. The results of this study suggest that in addition to its utility for monitoring the presence of clastogens in ambient air and water, the Trad-MN assay also be used as a reliable test system for detecting the levels of clastogens in soil. |
| Supplementary Notes |
Pub. in Mutation Research, v270 n1 p65-69 Nov 92. Prepared in cooperation with Environmental Health Research and Testing, Inc., Research Triangle Park, NC. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Application of the 'Tradescantia micronucleus' Assay for the Genetic Evaluation of Chemical Mixtures in Soil and Aqueous Media. |
| Category Codes |
57Y; 57F; 57C; 68C |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/10 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
307031459 |
| Origin |
NTIS |
| Type |
CAT |
