| Main Title |
A biologic indicator for air pollution / |
| Author |
Sherwin, Russell P.
|
| CORP Author |
Los Angeles County-Univ. of Southern California Medical Center.;Health Effects Research Lab., Research Triangle Park, NC. |
| Publisher |
U.S. Environmental Protection Agency, Health Effects Research Laboratory ; For sale by the National Technical Information Service, |
| Year Published |
1979 |
| Report Number |
EPA 600/1-79/038; EPA-R-800881; EPA-R-804545 |
| Stock Number |
PB80-143274 |
| OCLC Number |
37860107 |
| Subjects |
Nitrogen dioxide--Physiological effect ;
Air--Pollution--Physiological effect
|
| Additional Subjects |
Indicator species ;
Nitrogen dioxide ;
Exposure ;
Guinea pigs ;
Mice ;
Laboratory animals ;
Cells(Biology) ;
Protein ;
Lung ;
Air pollution ;
Electrophoresis ;
Kinetics ;
Ultraviolet radiation ;
Bioindicators ;
Air pollution effects(Animals)
|
| Internet Access |
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| EJBD |
EPA 600-1-79-038 |
c.1 |
Headquarters Library/Washington,DC |
04/28/2014 |
| EKBD |
EPA-600/1-79-038 |
|
Research Triangle Park Library/RTP, NC |
06/01/2001 |
| ELBD ARCHIVE |
EPA 600-1-79-038 |
Received from HQ |
AWBERC Library/Cincinnati,OH |
10/04/2023 |
| ELBD |
EPA 600-1-79-038 |
|
AWBERC Library/Cincinnati,OH |
11/15/2016 |
| NTIS |
PB80-143274 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
xi, 71 pages : illustrations ; 28 cm |
| Abstract |
The report describes studies wherein guinea pigs and mice were exposed to low levels of nitrogen dioxide either continuously or on an intermittent schedule. The major objective was to develop highly sensitive discriminants involving correlations of structural and functional alterations. The two major test areas developed were the quantitative measurements of Type 2 cell populations and protein leakage within the lung. The increase in number and size of Type 2 pneumocytes with NO2 exposure is believed to represent a corresponding loss of Type 1 lung cells, and the protein leakage within the lung is in accord with the concept that the Type 1 cell is a critical barrier for fluid transport in the alveolar area. The authors suggest that their research data supports the hypothesis that to properly evaluate the possible health effects from air pollutants one must give attention to the subclinical cellular alterations that deplete the functional and structural reserves of organs which are the primary target for air pollutants. |
| Notes |
Grants no. R800881 and R804545. "EPA-600/1-79-038." Project officer: Donald E. Gardner. Includes bibliographical references (pages 68-70). |
| Place Published |
Research Triangle Park, NC Springfield, Va. |
| Access Notes |
Also available via the World Wide Web. |
| Corporate Au Added Ent |
Health Effects Research Laboratory (Research Triangle Park, N.C.); United States. Environmental Protection Agency. Office of Research and Development. |
| Corp Au Ser Add Ent |
Environmental health effects research series ; EPA-600/1-79-038. United States. ; Environmental health effects research series ; EPA-600/1-79-038. United States. ; Environmental health effects research series ; EPA-600/1-79-038. United States. |
| Title Ser Add Ent |
Research reporting series Environmental health effects research ; |
| PUB Date Free Form |
September 1979 |
| Series Title Untraced |
Environmental health effects research series ; EPA-600/1-79-038 |
| NTIS Prices |
PC A03/MF A01 |
| BIB Level |
m |
| Medium |
unmediated |
| Content |
text |
| Carrier |
volume |
| Cataloging Source |
OCLC/T |
| OCLC Time Stamp |
20161028072212 |
| Language |
eng |
| Origin |
OCLC |
| Type |
MERGE |
| OCLC Rec Leader |
02028cam 2200493Ka 45010 |
