| Main Title |
Tissue Cell Culture Study of dow Corning 360 Medical Fluid, with Cover Letter dated 4/20/94. |
| CORP Author |
Dow Corning Corp., Midland, MI.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1994 |
| Report Number |
86940001435 |
| Stock Number |
OTS0558165 |
| Additional Subjects |
Toxicology ;
Health effects ;
Siloxanes and Silicones (63148-62-9) ;
Acute Toxicity ;
Mammals ;
Humans ;
In Vitro ;
Toxic substances ;
Laboratory animals ;
CAS No 63148-62-9
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0558165 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
35p |
| Abstract |
A tissue culture cytotoxicity study was conducted to evaluate the biocompatibility of polydimethylsiloxane fluid with human cells. The negative control was Silastic 372; while Latex catheter served as the positive control. Extracts of the test and control substances were prepared by heating samples in either cottonseed oil, 0.9 percent sodium chloride, or MEM tissue culture media. Each test material and each extract were placed in direct contact with a confluent monolayer of human embryonic lung cells and incubated for 24 hours. After incubation, the cultures were examined microscopically at 10x magnification and compared to positive and negative controls to evaluate cytotoxicity. No cytopathic effects were reported for polydimethylsiloxane fluid or its extracts. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
1994 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A04/MF A04 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
028803890 |
| Origin |
NTIS |
| Type |
CAT |
